Orphan nuclear receptor TLX recruits histone deacetylases to repress transcription and regulate neural stem cell proliferation
about
Protein evolution by molecular tinkering: diversification of the nuclear receptor superfamily from a ligand-dependent ancestorZNF536, a novel zinc finger protein specifically expressed in the brain, negatively regulates neuron differentiation by repressing retinoic acid-induced gene transcriptionEpigenetic choreographers of neurogenesis in the adult mammalian brainSignaling mechanisms regulating adult neural stem cells and neurogenesisA feedback regulatory loop involving microRNA-9 and nuclear receptor TLX in neural stem cell fate determinationEpigenetic control on cell fate choice in neural stem cellsSIRT1 and SIRT2: emerging targets in neurodegenerationNeural stem cell niches in health and diseasesUnlocking epigenetic codes in neurogenesisTLX: A master regulator for neural stem cell maintenance and neurogenesismiR-9 and TLX: chasing tails in neural stem cellsThe protective effect of melatonin on neural stem cell against LPS-induced inflammationThe oncoprotein BCL11A binds to orphan nuclear receptor TLX and potentiates its transrepressive functionThe human orphan nuclear receptor tailless (TLX, NR2E1) is druggableHistone demethylase LSD1 regulates neural stem cell proliferationThe nuclear receptor TLX is required for gliomagenesis within the adult neurogenic niche.Invasive Cell Fate Requires G1 Cell-Cycle Arrest and Histone Deacetylase-Mediated Changes in Gene ExpressionMicroRNA let-7b regulates neural stem cell proliferation and differentiation by targeting nuclear receptor TLX signaling.The nuclear receptor gene family in the Pacific oyster, Crassostrea gigas, contains a novel subfamily groupNuclear receptor TLX stimulates hippocampal neurogenesis and enhances learning and memory in a transgenic mouse modelEpigenetic regulation of adult neural stem cells: implications for Alzheimer's disease.Orphan nuclear receptor TLX activates Wnt/beta-catenin signalling to stimulate neural stem cell proliferation and self-renewal.Convergent microRNA actions coordinate neocortical development.A small molecule accelerates neuronal differentiation in the adult rat.The microRNA cluster miR-106b~25 regulates adult neural stem/progenitor cell proliferation and neuronal differentiation.Genome-wide profiling identified a set of miRNAs that are differentially expressed in glioblastoma stem cells and normal neural stem cells.Characterization of induced neural progenitors from skin fibroblasts by a novel combination of defined factors.Nuclear receptors in stem cells and their therapeutic potentialCharacterization of TLX expression in neural stem cells and progenitor cells in adult brains.MiR-9, -31, and -182 deregulation promote proliferation and tumor cell survival in colon cancer.Neural transcription factors: from embryos to neural stem cells.The role of microRNAs in human neural stem cells, neuronal differentiation and subtype specificationStructural basis for corepressor assembly by the orphan nuclear receptor TLX.Activation of postnatal neural stem cells requires nuclear receptor TLXGene regulatory networks in embryonic stem cells and brain development.Sox2, Tlx, Gli3, and Her9 converge on Rx2 to define retinal stem cells in vivo.Retinoic Acid Induces Embryonic Stem Cell Differentiation by Altering Both Encoding RNA and microRNA ExpressionCombined serial analysis of gene expression and transcription factor binding site prediction identifies novel-candidate-target genes of Nr2e1 in neocortex development.Epigenetic Control of Stem Cell Potential during Homeostasis, Aging, and DiseaseSRY-box-containing gene 2 regulation of nuclear receptor tailless (Tlx) transcription in adult neural stem cells
P2860
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P2860
Orphan nuclear receptor TLX recruits histone deacetylases to repress transcription and regulate neural stem cell proliferation
description
2007 nî lūn-bûn
@nan
2007 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Orphan nuclear receptor TLX re ...... neural stem cell proliferation
@ast
Orphan nuclear receptor TLX re ...... neural stem cell proliferation
@en
Orphan nuclear receptor TLX re ...... neural stem cell proliferation
@nl
type
label
Orphan nuclear receptor TLX re ...... neural stem cell proliferation
@ast
Orphan nuclear receptor TLX re ...... neural stem cell proliferation
@en
Orphan nuclear receptor TLX re ...... neural stem cell proliferation
@nl
prefLabel
Orphan nuclear receptor TLX re ...... neural stem cell proliferation
@ast
Orphan nuclear receptor TLX re ...... neural stem cell proliferation
@en
Orphan nuclear receptor TLX re ...... neural stem cell proliferation
@nl
P2093
P2860
P921
P3181
P356
P1476
Orphan nuclear receptor TLX re ...... neural stem cell proliferation
@en
P2093
Guoqiang Sun
Yanhong Shi
P2860
P304
P3181
P356
10.1073/PNAS.0704089104
P407
P577
2007-09-25T00:00:00Z