Is NF-kappaB a good target for cancer therapy? Hopes and pitfalls - Wikidata - awgldk - TriplyDB

Is NF-kappaB a good target for cancer therapy? Hopes and pitfalls

Is NF-kappaB a good target for cancer therapy? Hopes and pitfalls

http://www.wikidata.org/entity/Q24570128

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Protandim, a fundamentally new antioxidant approach in chemoprevention using mouse two-stage skin carcinogenesis as a model Brd4 maintains constitutively active NF-κB in cancer cells by binding to acetylated RelA OTULIN restricts Met1-linked ubiquitination to control innate immune signaling Inhibition of autophagy by TAB2 and TAB3 microRNA-146a inhibits G protein-coupled receptor-mediated activation of NF-κB by targeting CARD10 and COPS8 in gastric cancer Emerging roles for the non-canonical IKKs in cancer A20-binding inhibitor of nuclear factor-kappaB (NF-kappaB)-2 (ABIN-2) is an activator of inhibitor of NF-kappaB (IkappaB) kinase alpha (IKKalpha)-mediated NF-kappaB transcriptional activity The IKK complex contributes to the induction of autophagy Bioinformatic analysis reveals the expression of unique transcriptomic signatures in Zika virus infected human neural stem cells New insights into the mechanisms of green tea catechins in the chemoprevention of prostate cancer MicroRNAs in NF-kappaB signaling Post-Translational Modifications of RelB NF-κB Subunit and Associated Functions Therapies targeting cancer stem cells: Current trends and future challenges When ubiquitin meets NF-κB: a trove for anti-cancer drug development Roles of tumor necrosis factor receptor associated factor 3 (TRAF3) and TRAF5 in immune cell functions Nuclear factor kappa B role in inflammation associated gastrointestinal malignancies Mechanisms driving macrophage diversity and specialization in distinct tumor microenvironments and parallelisms with other tissues Anti-tumor activity of non-steroidal anti-inflammatory drugs: cyclooxygenase-independent targets Beyond NF-κB activation: nuclear functions of IκB kinase α Withaferin A disrupts ubiquitin-based NEMO reorganization induced by canonical NF-κB signaling Cyclopia extracts act as ERα antagonists and ERβ agonists, in vitro and in vivo Gene expression signature of DMBA-induced hamster buccal pouch carcinomas: modulation by chlorophyllin and ellagic acid Serine/Threonine Kinase MLK4 Determines Mesenchymal Identity in Glioma Stem Cells in an NF-κB-dependent Manner.Mutations in NFKB2 and potential genetic heterogeneity in patients with DAVID syndrome, having variable endocrine and immune deficiencies Phytochemicals that regulate neurodegenerative disease by targeting neurotrophins: a comprehensive review The Plasmodium circumsporozoite protein, a novel NF-κB inhibitor, suppresses the growth of SW480 Quantitative proteomics reveals cellular targets of celastrol Lupeol is one of active components in the extract of Chrysanthemum indicum Linne that inhibits LMP1-induced NF-κB activation Effusanin E suppresses nasopharyngeal carcinoma cell growth by inhibiting NF-κB and COX-2 signaling NF-kappaB in lung cancer, a carcinogenesis mediator and a prevention and therapy target miRNA-133 augments coelomocyte phagocytosis in bacteria-challenged Apostichopus japonicus via targeting the TLR component of IRAK-1 in vitro and in vivo.Exploiting synthetic lethality for the therapy of ABC diffuse large B cell lymphoma Reduced susceptibility to colitis-associated colon carcinogenesis in mice lacking plasma membrane-associated sialidase Genetic diversity of EBV-encoded LMP1 in the Swiss HIV Cohort Study and implication for NF-Κb activation Non inflammatory boronate based glucose-responsive insulin delivery systems STATs in cancer inflammation and immunity: a leading role for STAT3 Autophagy and the integrated stress response Targeting MYC dependence in cancer by inhibiting BET bromodomains Protein structure: 'shear' clarity of IKKβ crystal.Disruption of IkappaB kinase (IKK)-mediated RelA serine 536 phosphorylation sensitizes human multiple myeloma cells to histone deacetylase (HDAC) inhibitors.

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Is NF-kappaB a good target for cancer therapy? Hopes and pitfalls

http://www.wikidata.org/entity/Q24570128

description

2009 nî lūn-bûn

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2009 թուականի Յունուարին հրատարակուած գիտական յօդուած

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2009 թվականի հունվարին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

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name

Is NF-kappaB a good target for cancer therapy? Hopes and pitfalls

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Is NF-kappaB a good target for cancer therapy? Hopes and pitfalls

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Is NF-kappaB a good target for cancer therapy? Hopes and pitfalls

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Is NF-kappaB a good target for cancer therapy? Hopes and pitfalls

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Is NF-kappaB a good target for cancer therapy? Hopes and pitfalls

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Is NF-kappaB a good target for cancer therapy? Hopes and pitfalls

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Is NF-kappaB a good target for cancer therapy? Hopes and pitfalls

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Is NF-kappaB a good target for cancer therapy? Hopes and pitfalls

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Is NF-kappaB a good target for cancer therapy? Hopes and pitfalls

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Nature Reviews Drug Discovery

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Is NF-kappaB a good target for cancer therapy? Hopes and pitfalls

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The Hallmarks of Cancer

NF-kappaB-inducing kinase regulates the processing of NF-kappaB2 p100

TNF-RII and c-IAP1 mediate ubiquitination and degradation of TRAF2

IAP antagonists induce autoubiquitination of c-IAPs, NF-kappaB activation, and TNFalpha-dependent apoptosis

IAP antagonists target cIAP1 to induce TNFalpha-dependent apoptosis

A novel family of putative signal transducers associated with the cytoplasmic domain of the 75 kDa tumor necrosis factor receptor

The tumor necrosis factor receptor 2 signal transducers TRAF2 and c-IAP1 are components of the tumor necrosis factor receptor 1 signaling complex

Specificity of TRAF3 in its negative regulation of the noncanonical NF-kappa B pathway

Identification and validation of oncogenes in liver cancer using an integrative oncogenomic approach

Characterizing the cancer genome in lung adenocarcinoma.

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1

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1039639004

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2729321

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