Gene therapy rescues cone function in congenital achromatopsia.
about
The genetics of normal and defective color visionA comprehensive review of retinal gene therapyCanine CNGA3 Gene Mutations Provide Novel Insights into Human Achromatopsia-Associated Channelopathies and TreatmentGene Augmentation Therapy Restores Retinal Function and Visual Behavior in a Sheep Model of CNGA3 AchromatopsiaAdvancing therapeutic strategies for inherited retinal degeneration: recommendations from the Monaciano SymposiumMutations in the unfolded protein response regulator ATF6 cause the cone dysfunction disorder achromatopsiaGenetic and phenotypic variations of inherited retinal diseases in dogs: the power of within- and across-breed studiesAAV-mediated cone rescue in a naturally occurring mouse model of CNGA3-achromatopsiaCNTF and retinaThe human rhodopsin kinase promoter in an AAV5 vector confers rod- and cone-specific expression in the primate retina.Successful gene therapy in the RPGRIP1-deficient dog: a large model of cone-rod dystrophy.Functional and behavioral restoration of vision by gene therapy in the guanylate cyclase-1 (GC1) knockout mouse.Adaptive optics retinal imaging--clinical opportunities and challengesPRE-1, a cis element sufficient to enhance cone- and rod- specific expression in differentiating zebrafish photoreceptorsIn vivo imaging of human cone photoreceptor inner segments.A Quantitative and Qualitative Exploration of Photoaversion in Achromatopsia.An extended 15 Hz ERG protocol (2): data of normal subjects and patients with achromatopsia, CSNB1, and CSNB2.A novel form of progressive retinal atrophy in Swedish vallhund dogsA prospective longitudinal study of retinal structure and function in achromatopsia.CNGB3-achromatopsia clinical trial with CNTF: diminished rod pathway responses with no evidence of improvement in cone functionDark-adaptation functions in molecularly confirmed achromatopsia and the implications for assessment in retinal therapy trials.Assessment of canine BEST1 variations identifies new mutations and establishes an independent bestrophinopathy model (cmr3).The genetics of eye disorders in the dogSuccessful arrest of photoreceptor and vision loss expands the therapeutic window of retinal gene therapy to later stages of disease.Genotype-dependent variability in residual cone structure in achromatopsia: toward developing metrics for assessing cone healthA digital atlas of the dog brainVector platforms for gene therapy of inherited retinopathies.AAV9 targets cone photoreceptors in the nonhuman primate retina.Evaluation of lateral spread of transgene expression following subretinal AAV-mediated gene delivery in dogsGenomic deletion of CNGB3 is identical by descent in multiple canine breeds and causes achromatopsia.Five novel CNGB3 gene mutations in Polish patients with achromatopsiaA large animal model for CNGB1 autosomal recessive retinitis pigmentosa.Clinical characteristics and current therapies for inherited retinal degenerationsUp-regulation of tumor necrosis factor superfamily genes in early phases of photoreceptor degenerationA cyclic nucleotide-gated channel mutation associated with canine daylight blindness provides insight into a role for the S2 segment tri-Asp motif in channel biogenesis.Long-term and age-dependent restoration of visual function in a mouse model of CNGB3-associated achromatopsia following gene therapyNatural history of cone disease in the murine model of Leber congenital amaurosis due to CEP290 mutation: determining the timing and expectation of therapy.Gene therapy for choroideremia using an adeno-associated viral (AAV) vector.Molecular consequences of BEST1 gene mutations in canine multifocal retinopathy predict functional implications for human bestrophinopathies.Personalized therapeutic strategies for patients with retinitis pigmentosa.
P2860
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P2860
Gene therapy rescues cone function in congenital achromatopsia.
description
2010 nî lūn-bûn
@nan
2010 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Gene therapy rescues cone function in congenital achromatopsia
@nl
Gene therapy rescues cone function in congenital achromatopsia.
@ast
Gene therapy rescues cone function in congenital achromatopsia.
@en
type
label
Gene therapy rescues cone function in congenital achromatopsia
@nl
Gene therapy rescues cone function in congenital achromatopsia.
@ast
Gene therapy rescues cone function in congenital achromatopsia.
@en
prefLabel
Gene therapy rescues cone function in congenital achromatopsia
@nl
Gene therapy rescues cone function in congenital achromatopsia.
@ast
Gene therapy rescues cone function in congenital achromatopsia.
@en
P2093
P2860
P3181
P356
P1476
Gene therapy rescues cone function in congenital achromatopsia.
@en
P2093
András M Komáromy
Gregory M Acland
Gustavo D Aguirre
Jacqueline C Tanaka
Jessica S Rowlan
John J Alexander
Monique M Garcia
Vince A Chiodo
William W Hauswirth
P2860
P304
P3181
P356
10.1093/HMG/DDQ136
P407
P577
2010-04-08T00:00:00Z