Pharmacokinetics, oral bioavailability, and metabolic profile of resveratrol and its dimethylether analog, pterostilbene, in rats - Wikidata - awgldk - TriplyDB

Pharmacokinetics, oral bioavailability, and metabolic profile of resveratrol and its dimethylether analog, pterostilbene, in rats

Pharmacokinetics, oral bioavailability, and metabolic profile of resveratrol and its dimethylether analog, pterostilbene, in rats

http://www.wikidata.org/entity/Q24597042

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Coadjuvants in the Diabetic Complications: Nutraceuticals and Drugs with Pleiotropic Effects Resveratrol and Ophthalmic Diseases Role of Natural Stilbenes in the Prevention of Cancer An Organ System Approach to Explore the Antioxidative, Anti-Inflammatory, and Cytoprotective Actions of Resveratrol Polyphenol Stilbenes: Molecular Mechanisms of Defence against Oxidative Stress and Aging-Related Diseases Polyphenols and the human brain: plant “secondary metabolite” ecologic roles and endogenous signaling functions drive benefits A review of pterostilbene antioxidant activity and disease modification Idebenone and resveratrol extend lifespan and improve motor function of HtrA2 knockout mice Resveratrol acts not through anti-aggregative pathways but mainly via its scavenging properties against Aβ and Aβ-metal complexes toxicity Pterostilbene acts through metastasis-associated protein 1 to inhibit tumor growth, progression and metastasis in prostate cancer Identification of resveratrol oligomers as inhibitors of cystic fibrosis transmembrane conductance regulator by high-throughput screening of natural products from chinese medicinal plants Anticancer activities of pterostilbene-isothiocyanate conjugate in breast cancer cells: involvement of PPARγ Pterostilbene-isothiocyanate conjugate suppresses growth of prostate cancer cells irrespective of androgen receptor status Pterostilbene simultaneously induced G0/G1-phase arrest and MAPK-mediated mitochondrial-derived apoptosis in human acute myeloid leukemia cell lines Stabilization of resveratrol in blood circulation by conjugation to mPEG and mPEG-PLA polymers: investigation of conjugate linker and polymer composition on stability, metabolism, antioxidant activity and pharmacokinetic profile Case-specific potentiation of glioblastoma drugs by pterostilbene Resveratrol worsens survival in SCID mice with prostate cancer xenografts in a cell-line specific manner, through paradoxical effects on oncogenic pathways In vitro and in vivo activities of pterostilbene against Candida albicans biofilms.Pterostilbene, a Methoxylated Resveratrol Derivative, Efficiently Eradicates Planktonic, Biofilm, and Intracellular MRSA by Topical Application.Anticancer Activity of Pterostilbene in Human Ovarian Cancer Cell Lines Pterostilbene on metabolic parameters: a randomized, double-blind, and placebo-controlled trial.Biosynthesis of methylated resveratrol analogs through the construction of an artificial biosynthetic pathway in E. coli.Calorie restriction combined with resveratrol induces autophagy and protects 26-month-old rat hearts from doxorubicin-induced toxicity Fatty acid synthase methylation levels in adipose tissue: effects of an obesogenic diet and phenol compounds.Genomic analysis of pterostilbene predicts its antiproliferative effects against pancreatic cancer in vitro and in vivo Resveratrol potentiates the in vitro and in vivo anti-tumoral effects of curcumin in head and neck carcinomas Resveratrol analogs: promising chemopreventive agents.Grape polyphenols inhibit Akt/mammalian target of rapamycin signaling and potentiate the effects of gefitinib in breast cancer.Resveratrol derivatives: a patent review (2009 - 2012).Resveratrol metabolism in a non-human primate, the grey mouse lemur (Microcebus murinus), using ultra-high-performance liquid chromatography-quadrupole time of flight New multi-target-directed small molecules against Alzheimer's disease: a combination of resveratrol and clioquinol.Inhibitory effects of resveratrol and pterostilbene on human colon cancer cells: a side-by-side comparison Pterostilbene attenuates inflammation in rat heart subjected to ischemia-reperfusion: role of TLR4/NF-κB signaling pathway Determination of resveratrol and its sulfate and glucuronide metabolites in plasma by LC-MS/MS and their pharmacokinetics in dogs.Targeting host nucleotide biosynthesis with resveratrol inhibits emtricitabine-resistant HIV-1.Differences in the glucuronidation of resveratrol and pterostilbene: altered enzyme specificity and potential gender differences Analytical method development for synthesized conjugated metabolites of trans-resveratrol, and application to pharmacokinetic studies.Stilbene derivatives promote Ago2-dependent tumour-suppressive microRNA activity Resveratrol Antagonizes Antimicrobial Lethality and Stimulates Recovery of Bacterial Mutants.In vivo-formed versus preformed metabolite kinetics of trans-resveratrol-3-sulfate and trans-resveratrol-3-glucuronide.

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Pharmacokinetics, oral bioavailability, and metabolic profile of resveratrol and its dimethylether analog, pterostilbene, in rats

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2011 nî lūn-bûn

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2011 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

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Cancer Chemotherapy and Pharmacology

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David L McCormick

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Izet M Kapetanovic

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Miguel Muzzio

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Thomas N Thompson

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Zhihua Huang

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P2860

Multiple molecular targets of resveratrol: Anti-carcinogenic mechanisms

Resveratrol: a review of preclinical studies for human cancer prevention

Human UDP-glucuronosyltransferases: metabolism, expression, and disease

Cancer prevention and treatment with resveratrol: from rodent studies to clinical trials

Cancer chemopreventive activity of resveratrol, a natural product derived from grapes

Therapeutic potential of resveratrol: the in vivo evidence

Identification of molecular pathways affected by pterostilbene, a natural dimethylether analog of resveratrol.

Determination of pterostilbene in rat plasma by a simple HPLC-UV method and its application in pre-clinical pharmacokinetic study.

Dietary intake of pterostilbene, a constituent of blueberries, inhibits the beta-catenin/p65 downstream signaling pathway and colon carcinogenesis in rats

Selective synthesis and biological evaluation of sulfate-conjugated resveratrol metabolites.

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