ADAR1 RNA deaminase limits short interfering RNA efficacy in mammalian cells
about
Anti-viral RNA silencing: do we look like plants?Alu sequences in undifferentiated human embryonic stem cells display high levels of A-to-I RNA editingThe editing enzyme ADAR1 and the mRNA surveillance protein hUpf1 interact in the cell nucleusHuman endonuclease V is a ribonuclease specific for inosine-containing RNAModulation of microRNA processing and expression through RNA editing by ADAR deaminasesEditor meets silencer: crosstalk between RNA editing and RNA interferenceA left-handed RNA double helix bound by the Z alpha domain of the RNA-editing enzyme ADAR1Cleavage of dsRNAs hyper-edited by ADARs occurs at preferred editing sitesDiversity of Endonuclease V: From DNA Repair to RNA EditingDysregulation of microRNA expression and function contributes to the etiology of fetal alcohol spectrum disordersA-to-I RNA Editing: Current Knowledge Sources and Computational Approaches with Special Emphasis on Non-Coding RNA MoleculesEnhancement of replication of RNA viruses by ADAR1 via RNA editing and inhibition of RNA-activated protein kinaseEditing independent effects of ADARs on the miRNA/siRNA pathwaysFunctions and regulation of RNA editing by ADAR deaminasesMutations in ADAR1 cause Aicardi-Goutières syndrome associated with a type I interferon signatureEditing of hnRNP K protein mRNA in colorectal adenocarcinoma and surrounding mucosaAdenosine deaminases acting on RNA (ADARs) are both antiviral and proviralADAR1 is required for hematopoietic progenitor cell survival via RNA editingADAR1 ablation decreases bone mass by impairing osteoblast function in miceAlu mobile elements: from junk DNA to genomic gemsHow does RNA editing affect dsRNA-mediated gene silencing?Molecular diversity through RNA editing: a balancing act.A-to-I RNA editing and human disease.RNA binding-independent dimerization of adenosine deaminases acting on RNA and dominant negative effects of nonfunctional subunits on dimer functions.Adenosine deaminase acting on RNA 1 limits RIG-I RNA detection and suppresses IFN production responding to viral and endogenous RNAs.Regulation of small RNA stability: methylation and beyond.Substitutional A-to-I RNA editing.Altered RNA editing in mice lacking ADAR2 autoregulation.Minor-groove-modulating adenosine replacements control protein binding and RNAi activity in siRNAsAdenosine deaminases acting on RNA, RNA editing, and interferon action.Development of resistance to RNAi in mammalian cellsPrediction of constitutive A-to-I editing sites from human transcriptomes in the absence of genomic sequences.8-Oxoguanosine switches modulate the activity of alkylated siRNAs by controlling steric effects in the major versus minor grooves.A structural determinant required for RNA editing.Controlling activation of the RNA-dependent protein kinase by siRNAs using site-specific chemical modificationCompetition between ADAR and RNAi pathways for an extensive class of RNA targets.Genome-wide profiling of the C. elegans dsRNAome.dsRNA expression in the mouse elicits RNAi in oocytes and low adenosine deamination in somatic cells.Short-term induction and long-term suppression of HPV16 oncogene silencing by RNA interference in cervical cancer cellsRNA editing of the microRNA-151 precursor blocks cleavage by the Dicer-TRBP complex.
P2860
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P2860
ADAR1 RNA deaminase limits short interfering RNA efficacy in mammalian cells
description
2005 nî lūn-bûn
@nan
2005 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
ADAR1 RNA deaminase limits short interfering RNA efficacy in mammalian cells
@ast
ADAR1 RNA deaminase limits short interfering RNA efficacy in mammalian cells
@en
ADAR1 RNA deaminase limits short interfering RNA efficacy in mammalian cells
@nl
type
label
ADAR1 RNA deaminase limits short interfering RNA efficacy in mammalian cells
@ast
ADAR1 RNA deaminase limits short interfering RNA efficacy in mammalian cells
@en
ADAR1 RNA deaminase limits short interfering RNA efficacy in mammalian cells
@nl
prefLabel
ADAR1 RNA deaminase limits short interfering RNA efficacy in mammalian cells
@ast
ADAR1 RNA deaminase limits short interfering RNA efficacy in mammalian cells
@en
ADAR1 RNA deaminase limits short interfering RNA efficacy in mammalian cells
@nl
P2093
P2860
P356
P1476
ADAR1 RNA deaminase limits short interfering RNA efficacy in mammalian cells
@en
P2093
Dan-Sung C Cho
John M Murray
Joshua T Lee
Kazuko Nishikura
Kelly L Howell
Qingde Wang
Weidong Yang
P2860
P304
P356
10.1074/JBC.M407876200
P407
P577
2005-02-04T00:00:00Z