LP-211 is a brain penetrant selective agonist for the serotonin 5-HT(7) receptor
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Serotonin 5-HT7 receptor agents: Structure-activity relationships and potential therapeutic applications in central nervous system disordersThe serotonin receptor 7 and the structural plasticity of brain circuitsLow-basicity 5-HT7 Receptor Agonists Synthesized Using the van Leusen Multicomponent Protocol5-HT7 receptors as modulators of neuronal excitability, synaptic transmission and plasticity: physiological role and possible implications in autism spectrum disorders.Interplay between serotonin 5-HT1A and 5-HT7 receptors in depressive disorders.Prepuberal stimulation of 5-HT7-R by LP-211 in a rat model of hyper-activity and attention-deficit: permanent effects on attention, brain amino acids and synaptic markers in the fronto-striatal interface.Long-lasting beneficial effects of central serotonin receptor 7 stimulation in female mice modeling Rett syndromeEditorial: Further Understanding of Serotonin 7 Receptors' Neuro-psycho-pharmacologyThe 5-HT7 receptor as a potential target for treating drug and alcohol abuse.The arylpiperazine derivatives N-(4-cyanophenylmethyl)-4-(2-diphenyl)-1-piperazinehexanamide and N-benzyl-4-(2-diphenyl)-1-piperazinehexanamide exert a long-lasting inhibition of human serotonin 5-HT7 receptor binding and cAMP signaling.Serotonin 5-HT7 receptor increases the density of dendritic spines and facilitates synaptogenesis in forebrain neurons.Antipsychotic inductors of brain hypothermia and torpor-like states: perspectives of application.Activation of 5-HT7 receptor stimulates neurite elongation through mTOR, Cdc42 and actin filaments dynamics.Differential responses to acute administration of a new 5-HT7-R agonist as a function of adolescent pre-treatment: phMRI and immuno-histochemical study.The brain-penetrant 5-HT7 receptor agonist LP-211 reduces the sensory and affective components of neuropathic pain.Assessment of 5-HT(7) Receptor Agonists Selectivity Using Nociceptive and Thermoregulation Tests in Knockout versus Wild-Type Mice.Pharmacological stimulation of the brain serotonin receptor 7 as a novel therapeutic approach for Rett syndrome.Novel agonists for serotonin 5-HT7 receptors reverse metabotropic glutamate receptor-mediated long-term depression in the hippocampus of wild-type and Fmr1 KO mice, a model of Fragile X Syndrome.RETRACTED: Serotonin 5-HT7 receptor agonist, LP-211, exacerbates Na(+), K(+)-ATPase/Mg(2+)-ATPase imbalances in spinal cord-injured male rats.Increase of capsaicin-induced trigeminal Fos-like immunoreactivity by 5-HT(7) receptors.Emotional and risk seeking behavior after prepuberal subchronic or adult acute stimulation of 5-HT7-Rs in Naples High Excitability rats.Stimulation of 5-HT7 receptor during adolescence determines its persistent upregulation in adult rat forebrain areas.Towards metabolically stable 5-HT7 receptor ligands: a study on 1-arylpiperazine derivatives and related isosters.Persistent modification of forebrain networks and metabolism in rats following adolescent exposure to a 5-HT7 receptor agonist.5-HT7 receptor activation: procognitive and antiamnesic effects.Activation of Serotonin 5-HT Receptors Modulates Hippocampal Synaptic Plasticity by Stimulation of Adenylate Cyclases and Rescues Learning and Behavior in a Mouse Model of Fragile X Syndrome
P2860
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P2860
LP-211 is a brain penetrant selective agonist for the serotonin 5-HT(7) receptor
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2010 nî lūn-bûn
@nan
2010 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2010年の論文
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2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
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name
LP-211 is a brain penetrant selective agonist for the serotonin 5-HT(7) receptor
@ast
LP-211 is a brain penetrant selective agonist for the serotonin 5-HT(7) receptor
@en
LP-211 is a brain penetrant selective agonist for the serotonin 5-HT(7) receptor
@nl
type
label
LP-211 is a brain penetrant selective agonist for the serotonin 5-HT(7) receptor
@ast
LP-211 is a brain penetrant selective agonist for the serotonin 5-HT(7) receptor
@en
LP-211 is a brain penetrant selective agonist for the serotonin 5-HT(7) receptor
@nl
prefLabel
LP-211 is a brain penetrant selective agonist for the serotonin 5-HT(7) receptor
@ast
LP-211 is a brain penetrant selective agonist for the serotonin 5-HT(7) receptor
@en
LP-211 is a brain penetrant selective agonist for the serotonin 5-HT(7) receptor
@nl
P2093
P2860
P50
P1433
P1476
LP-211 is a brain penetrant selective agonist for the serotonin 5-HT(7) receptor
@en
P2093
Claudia Fracasso
Francesco Berardi
Giuliana Martelli
Gor Sarkisyan
Peter B Hedlund
Silvio Caccia
P2860
P356
10.1016/J.NEULET.2010.06.036
P407
P577
2010-06-23T00:00:00Z