about
HIV-1 envelope-receptor interactions required for macrophage infection and implications for current HIV-1 cure strategiesNon-simian foamy viruses: molecular virology, tropism and prevalence and zoonotic/interspecies transmissionCo-evolution of primate SAMHD1 and lentivirus Vpx leads to the loss of the vpx gene in HIV-1 ancestorReacquisition of Nef-mediated tetherin antagonism in a single in vivo passage of HIV-1 through its original chimpanzee hostImmunopathogenesis of simian immunodeficiency virus infection in nonhuman primatesEfficient transduction of myeloid cells by an HIV-1-derived lentiviral vector that packages the Vpx accessory proteinMouse knockout models for HIV-1 restriction factors.Immune activation and HIV persistence: implications for curative approaches to HIV infection.SAMHD1 is mutated recurrently in chronic lymphocytic leukemia and is involved in response to DNA damage.Identification of regulators of the innate immune response to cytosolic DNA and retroviral infection by an integrative approach.HIV-1 pathogenicity and virion production are dependent on the metabolic phenotype of activated CD4+ T cellsCombinatorial anti-HIV gene therapy: using a multipronged approach to reach beyond HAARTIdentification of critical regions in human SAMHD1 required for nuclear localization and Vpx-mediated degradationIdentification of potential HIV restriction factors by combining evolutionary genomic signatures with functional analysesPotent Cell-Intrinsic Immune Responses in Dendritic Cells Facilitate HIV-1-Specific T Cell Immunity in HIV-1 Elite Controllers.Role of SAMHD1 nuclear localization in restriction of HIV-1 and SIVmac.SAMHD1 restricts HIV-1 infection in dendritic cells (DCs) by dNTP depletion, but its expression in DCs and primary CD4+ T-lymphocytes cannot be upregulated by interferonsNatural Immunity to HIV: a delicate balance between strength and control.The efficiency of Vpx-mediated SAMHD1 antagonism does not correlate with the potency of viral control in HIV-2-infected individuals.Heterozygous colon cancer-associated mutations of SAMHD1 have functional significanceSAMHD1 restricts herpes simplex virus 1 in macrophages by limiting DNA replication.Cellular and Biochemical Mechanisms of the Retroviral Restriction Factor SAMHD1.Lentivirus Vpr and Vpx accessory proteins usurp the cullin4-DDB1 (DCAF1) E3 ubiquitin ligase.Interferon-stimulated genes: roles in viral pathogenesis.SAMHD1's protein expression profile in humans.Viruses transfer the antiviral second messenger cGAMP between cells.Variation of two primate lineage-specific residues in human SAMHD1 confers resistance to N terminus-targeted SIV Vpx proteins.Keeping your armour intact: how HIV-1 evades detection by the innate immune system: HIV-1 capsid controls detection of reverse transcription products by the cytosolic DNA sensor cGAS.Polymorphisms of the SAMHD1 gene are not associated with the infection and natural control of HIV type 1 in Europeans and African-Americans.Tripartite Motif 22 and Class II Transactivator Restriction Factors: Unveiling Their Concerted Action against Retroviruses.The role of SAMHD1 expression and its relation to HIV-2 (Vpx) gene production
P2860
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P2860
description
2012 nî lūn-bûn
@nan
2012 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
How SAMHD1 changes our view of viral restriction
@ast
How SAMHD1 changes our view of viral restriction
@en
How SAMHD1 changes our view of viral restriction
@nl
type
label
How SAMHD1 changes our view of viral restriction
@ast
How SAMHD1 changes our view of viral restriction
@en
How SAMHD1 changes our view of viral restriction
@nl
prefLabel
How SAMHD1 changes our view of viral restriction
@ast
How SAMHD1 changes our view of viral restriction
@en
How SAMHD1 changes our view of viral restriction
@nl
P2860
P356
P1433
P1476
How SAMHD1 changes our view of viral restriction
@en
P2093
Monsef Benkirane
Nadine Laguette
P2860
P356
10.1016/J.IT.2011.11.002
P407
P577
2012-01-01T00:00:00Z