S-Nitrosylation activates Cdk5 and contributes to synaptic spine loss induced by beta-amyloid peptide - Wikidata - awgldk - TriplyDB

S-Nitrosylation activates Cdk5 and contributes to synaptic spine loss induced by beta-amyloid peptide

S-Nitrosylation activates Cdk5 and contributes to synaptic spine loss induced by beta-amyloid peptide

http://www.wikidata.org/entity/Q24612303

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S-Nitrosylation Induces Structural and Dynamical Changes in a Rhodanese Family Protein Aβ induces astrocytic glutamate release, extrasynaptic NMDA receptor activation, and synaptic loss A Tale of the Good and Bad: Remodeling of the Microtubule Network in the Brain by Cdk5 Anti-diabetes drug pioglitazone ameliorates synaptic defects in AD transgenic mice by inhibiting cyclin-dependent kinase5 activity S-nitrosation of proteins relevant to Alzheimer's disease during early stages of neurodegeneration Aberrant protein S-nitrosylation contributes to the pathophysiology of neurodegenerative diseases Light-evoked S-nitrosylation in the retina.Mechanisms of nitrosylation and denitrosylation of cytoplasmic glyceraldehyde-3-phosphate dehydrogenase from Arabidopsis thaliana Cdk5 activity in the brain - multiple paths of regulation.CDK5-dependent inhibitory phosphorylation of Drp1 during neuronal maturation Global analysis of S-nitrosylation sites in the wild type (APP) transgenic mouse brain-clues for synaptic pathology.Transnitrosylation from DJ-1 to PTEN attenuates neuronal cell death in parkinson's disease models Oligomeric Aβ-induced synaptic dysfunction in Alzheimer's disease.Role of S-nitrosoglutathione mediated mechanisms in tau hyper-phosphorylation.S-nitroso-proteome in poplar leaves in response to acute ozone stress Regulation by S-nitrosylation of protein post-translational modification.Enzymatic mechanisms regulating protein S-nitrosylation: implications in health and disease.Nitric oxide and geriatrics: Implications in diagnostics and treatment of the elderly.S-nitrosylation-dependent proteasomal degradation restrains Cdk5 activity to regulate hippocampal synaptic strength.Protein S-Nitrosylation as a Therapeutic Target for Neurodegenerative Diseases.S-nitrosylated SHP-2 contributes to NMDA receptor-mediated excitotoxicity in acute ischemic stroke.Redox pioneer: Professor Stuart A. Lipton.S-nitrosylation of dynamin-related protein 1 mediates mutant huntingtin-induced mitochondrial fragmentation and neuronal injury in Huntington's disease.Specificity in S-nitrosylation: a short-range mechanism for NO signaling?Mass spectrometric phosphoproteome analysis of HIV-infected brain reveals novel phosphorylation sites and differential phosphorylation patterns.Hydrogen sulfide: a gasotransmitter of clinical relevance.Differential effects of synaptic and extrasynaptic NMDA receptors on Aβ-induced nitric oxide production in cerebrocortical neurons Multiple faces of dynamin-related protein 1 and its role in Alzheimer's disease pathogenesis Selective vulnerability of synaptic signaling and metabolism to nitrosative stress Emerging role of protein-protein transnitrosylation in cell signaling pathways.Redox regulation of protein misfolding, mitochondrial dysfunction, synaptic damage, and cell death in neurodegenerative diseases.Redox Regulation of Protein Function via Cysteine S-Nitrosylation and Its Relevance to Neurodegenerative Diseases.Small changes huge impact: the role of thioredoxin 1 in the regulation of apoptosis by S-nitrosylation.The intersection of amyloid β and tau in glutamatergic synaptic dysfunction and collapse in Alzheimer's disease.Aberrant protein s-nitrosylation in neurodegenerative diseases.Dysfunctional Mitochondrial Dynamics in the Pathophysiology of Neurodegenerative Diseases.S-Nitrosylation in Alzheimer's disease.S-nitrosation and neuronal plasticity.S-Nitrosylation in neurogenesis and neuronal development.The Role of Cdk5 in Alzheimer's Disease.

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S-Nitrosylation activates Cdk5 and contributes to synaptic spine loss induced by beta-amyloid peptide

http://www.wikidata.org/entity/Q24612303

description

2011 nî lūn-bûn

@nan

2011 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի օգոստոսին հրատարակված գիտական հոդված

@hy

2011年の論文

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2011年論文

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2011年論文

@zh-hant

2011年論文

@zh-hk

2011年論文

@zh-mo

2011年論文

@zh-tw

2011年论文

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name

S-Nitrosylation activates Cdk5 ...... nduced by beta-amyloid peptide

@ast

S-Nitrosylation activates Cdk5 ...... nduced by beta-amyloid peptide

@en

S-Nitrosylation activates Cdk5 ...... nduced by beta-amyloid peptide

@nl

type

label

S-Nitrosylation activates Cdk5 ...... nduced by beta-amyloid peptide

@ast

S-Nitrosylation activates Cdk5 ...... nduced by beta-amyloid peptide

@en

S-Nitrosylation activates Cdk5 ...... nduced by beta-amyloid peptide

@nl

prefLabel

S-Nitrosylation activates Cdk5 ...... nduced by beta-amyloid peptide

@ast

S-Nitrosylation activates Cdk5 ...... nduced by beta-amyloid peptide

@en

S-Nitrosylation activates Cdk5 ...... nduced by beta-amyloid peptide

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PNAS.1105172108

P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

S-Nitrosylation activates Cdk5 ...... nduced by beta-amyloid peptide

@en

P2093

Emily A Holland

http://www.w3.org/2001/XMLSchema#string

Gang Cao

http://www.w3.org/2001/XMLSchema#string

Jing Qu

http://www.w3.org/2001/XMLSchema#string

Scott R McKercher

http://www.w3.org/2001/XMLSchema#string

Stuart A Lipton

http://www.w3.org/2001/XMLSchema#string

Tomohiro Nakamura

http://www.w3.org/2001/XMLSchema#string

P2860

Paradigm shift in neuroprotection by NMDA receptor blockade: Memantine and beyond

An isoform of the neuronal cyclin-dependent kinase 5 (Cdk5) activator

Specific role of neuronal nitric-oxide synthase when tethered to the plasma membrane calcium pump in regulating the beta-adrenergic signal in the myocardium

p35 is a neural-specific regulatory subunit of cyclin-dependent kinase 5

Memantine preferentially blocks extrasynaptic over synaptic NMDA receptor currents in hippocampal autapses

Soluble amyloid beta peptide concentration as a predictor of synaptic change in Alzheimer's disease

A protein microarray-based analysis of S-nitrosylation.

Conversion of p35 to p25 deregulates Cdk5 activity and promotes neurodegeneration

Neurotoxicity induces cleavage of p35 to p25 by calpain

S-nitrosylated protein-disulphide isomerase links protein misfolding to neurodegeneration

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14330-5

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scholarly article

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10.1073/PNAS.1105172108

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34

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108

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51574071

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21844361

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3161554

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