Af9/Mllt3 interferes with Tbr1 expression through epigenetic modification of histone H3K79 during development of the cerebral cortex
about
From trans to cis: transcriptional regulatory networks in neocortical developmentNeuronal excitation upregulates Tbr1, a high-confidence risk gene of autism, mediating Grin2b expression in the adult brainHistone H3 lysine 79 methyltransferase Dot1 is required for immortalization by MLL oncogenes.Novel agents for the treatment of childhood acute leukemia.An Af9 cis-element directly targets Dot1a to mediate transcriptional repression of the αENaC geneAF9 promotes hESC neural differentiation through recruiting TET2 to neurodevelopmental gene loci for methylcytosine hydroxylation.The ZFP-1(AF10)/DOT-1 complex opposes H2B ubiquitination to reduce Pol II transcriptionCBX8, a component of the Polycomb PRC1 complex, modulates DOT1L-mediated gene expression through AF9/MLLT3Control of cerebral size and thickness.Getting down to the core of histone modifications.Histone methylation during neural development.Preclinical Pharmacokinetics and Pharmacodynamics of Pinometostat (EPZ-5676), a First-in-Class, Small Molecule S-Adenosyl Methionine Competitive Inhibitor of DOT1L.MicroRNA-297b-5p/3p target Mllt3/Af9 to suppress lymphoma cell proliferation, migration and invasion in vitro and tumor growth in nude mice.DOT1L Activity Promotes Proliferation and Protects Cortical Neural Stem Cells from Activation of ATF4-DDIT3-Mediated ER Stress In Vitro.Barcelona conference on epigenetics and cancer 2015: Coding and non-coding functions of the genome.Second German-Catalan workshop on epigenetics & cancer.PERIOD1 coordinates hippocampal rhythms and memory processing with daytime.Isolation and Cultivation of Neural Progenitors Followed by Chromatin-Immunoprecipitation of Histone 3 Lysine 79 Dimethylation Mark.Clocking In Time to Gate Memory Processes: The Circadian Clock Is Part of the Ins and Outs of Memory.Epigenetic and Transcriptional Pre-patterning—An Emerging Theme in Cortical Neurogenesis.The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6→ Tbr2→ Tbr1
P2860
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P2860
Af9/Mllt3 interferes with Tbr1 expression through epigenetic modification of histone H3K79 during development of the cerebral cortex
description
2010 nî lūn-bûn
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2010 թուականի Ապրիլին հրատարակուած գիտական յօդուած
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2010 թվականի ապրիլին հրատարակված գիտական հոդված
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2010年の論文
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2010年学术文章
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2010年学术文章
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2010年学术文章
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2010年学术文章
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2010年学术文章
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2010年學術文章
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name
Af9/Mllt3 interferes with Tbr1 ...... lopment of the cerebral cortex
@ast
Af9/Mllt3 interferes with Tbr1 ...... lopment of the cerebral cortex
@en
Af9/Mllt3 interferes with Tbr1 ...... lopment of the cerebral cortex
@nl
type
label
Af9/Mllt3 interferes with Tbr1 ...... lopment of the cerebral cortex
@ast
Af9/Mllt3 interferes with Tbr1 ...... lopment of the cerebral cortex
@en
Af9/Mllt3 interferes with Tbr1 ...... lopment of the cerebral cortex
@nl
prefLabel
Af9/Mllt3 interferes with Tbr1 ...... lopment of the cerebral cortex
@ast
Af9/Mllt3 interferes with Tbr1 ...... lopment of the cerebral cortex
@en
Af9/Mllt3 interferes with Tbr1 ...... lopment of the cerebral cortex
@nl
P2860
P356
P1476
Af9/Mllt3 interferes with Tbr1 ...... lopment of the cerebral cortex
@en
P2093
Nicole Büttner
Tanja Vogel
P2860
P304
P356
10.1073/PNAS.0912041107
P407
P577
2010-03-26T00:00:00Z