Structural and energetic basis of folded-protein transport by the FimD usher
about
Adhesive Pili in UTI Pathogenesis and Drug DevelopmentPost-expression strategies for structural investigations of membrane proteins.Computational modeling of membrane proteinsUrinary tract infections: epidemiology, mechanisms of infection and treatment optionsHybrid Structure of the Type 1 Pilus of Uropathogenic Escherichia coliFrom Constructs to Crystals - Towards Structure Determination of β-barrel Outer Membrane Proteins.Electrostatic networks control plug stabilization in the PapC usherLooks can be deceiving: recent insights into the mechanism of protein secretion by the autotransporter pathway.Structure-function analysis reveals that the Pseudomonas aeruginosa Tps4 two-partner secretion system is involved in CupB5 translocation.Allosteric signalling in the outer membrane translocation domain of PapC usher.Reconstitution of bacterial autotransporter assembly using purified components.Molecular basis of usher pore gating in Escherichia coli pilus biogenesisCharge-dependent secretion of an intrinsically disordered protein via the autotransporter pathway.Urinary Tract Infection: Pathogenesis and Outlook.Structure of a Chaperone-Usher Pilus Reveals the Molecular Basis of Rod Uncoiling.Evolutionary fine-tuning of conformational ensembles in FimH during host-pathogen interactions.Improving protein complex prediction by reconstructing a high-confidence protein-protein interaction network of Escherichia coli from different physical interaction data sourcesSyntheses and biological evaluation of 2-amino-3-acyl-tetrahydrobenzothiophene derivatives; antibacterial agents with antivirulence activityThe pilus usher controls protein interactions via domain masking and is functional as an oligomer.Antivirulence Isoquinolone Mannosides: Optimization of the Biaryl Aglycone for FimH Lectin Binding Affinity and Efficacy in the Treatment of Chronic UTI.The Escherichia coli P and Type 1 Pilus Assembly Chaperones PapD and FimC Are Monomeric in Solution.Positively selected FimH residues enhance virulence during urinary tract infection by altering FimH conformationOrdered and ushered; the assembly and translocation of the adhesive type I and p pili.Bacterial surface appendages as targets for novel antibacterial therapeutics.Suppression of type 1 pilus assembly in uropathogenic Escherichia coli by chemical inhibition of subunit polymerization.Protein folding in the cell envelope of Escherichia coli.Rational design strategies for FimH antagonists: new drugs on the horizon for urinary tract infection and Crohn's disease.Reversible non-stick behaviour of a bacterial protein polymer provides a tuneable molecular mimic for cell and tissue engineering.Molecular mechanism of bacterial type 1 and P pili assembly.Structure of a pathogenic type 3 secretion system in action.Lifting the lid on pilus assembly.Structural basis of host recognition and biofilm formation by Salmonella Saf pili.Outer membrane protein folding from an energy landscape perspective.The Cryoelectron Microscopy Structure of the Type 1 Chaperone-Usher Pilus Rod.Translocation through the conjugative Type 4 secretion system requires unfolding of its protein substrate.Analyzing the Role of Periplasmic Folding Factors in the Biogenesis of OMPs and Members of the Type V Secretion System.Secretion and functional display of fusion proteins through the curli biogenesis pathway.Mechanical architecture and folding of E. coli type 1 pilus domains.
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P2860
Structural and energetic basis of folded-protein transport by the FimD usher
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2013 nî lūn-bûn
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2013 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2013年の論文
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2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Structural and energetic basis of folded-protein transport by the FimD usher
@ast
Structural and energetic basis of folded-protein transport by the FimD usher
@en
Structural and energetic basis of folded-protein transport by the FimD usher
@nl
type
label
Structural and energetic basis of folded-protein transport by the FimD usher
@ast
Structural and energetic basis of folded-protein transport by the FimD usher
@en
Structural and energetic basis of folded-protein transport by the FimD usher
@nl
prefLabel
Structural and energetic basis of folded-protein transport by the FimD usher
@ast
Structural and energetic basis of folded-protein transport by the FimD usher
@en
Structural and energetic basis of folded-protein transport by the FimD usher
@nl
P2860
P50
P356
P1433
P1476
Structural and energetic basis of folded-protein transport by the FimD usher
@en
P2093
Scott J Hultgren
P2860
P2888
P356
10.1038/NATURE12007
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P577
2013-04-11T00:00:00Z
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P6179
1013644119