Astrocyte elevated gene-1 (AEG-1): A multifunctional regulator of normal and abnormal physiology - Wikidata - awgldk - TriplyDB

Astrocyte elevated gene-1 (AEG-1): A multifunctional regulator of normal and abnormal physiology

Astrocyte elevated gene-1 (AEG-1): A multifunctional regulator of normal and abnormal physiology

http://www.wikidata.org/entity/Q24616987

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Global profiling of dynamic protein palmitoylation Molecular mechanisms of cisplatin resistance in cervical cancer Metadherin regulates epithelial-mesenchymal transition in carcinoma AEG-1/MTDH/LYRIC: clinical significance Astrocyte elevated gene-1 promotes hepatocarcinogenesis: novel insights from a mouse model AEG-1/MTDH/LYRIC, the beginning: initial cloning, structure, expression profile, and regulation of expression Metadherin, p50, and p65 expression in epithelial ovarian neoplasms: an immunohistochemical study.Progress of cancer research on astrocyte elevated gene-1/Metadherin (Review).AEG-1 expression is an independent prognostic factor in rectal cancer patients with preoperative radiotherapy: a study in a Swedish clinical trial Astrocyte elevated gene-1 is a novel modulator of HIV-1-associated neuroinflammation via regulation of nuclear factor-κB signaling and excitatory amino acid transporter-2 repression.AEG-1 regulates retinoid X receptor and inhibits retinoid signaling.AEG-1 expression correlates with CD133 and PPP6c levels in human glioma tissues.Expression of astrocyte elevated gene-1 (AEG-1) as a biomarker for aggressive pancreatic ductal adenocarcinoma.MTDH mediates trastuzumab resistance in HER2 positive breast cancer by decreasing PTEN expression through an NFκB-dependent pathway Astrocyte elevated gene-1 interacts with Akt isoform 2 to control glioma growth, survival, and pathogenesis.Role of the staphylococcal nuclease and tudor domain containing 1 in oncogenesis (review).Quantitative analysis of the TNF-α-induced phosphoproteome reveals AEG-1/MTDH/LYRIC as an IKKβ substrate.Astrocyte elevated gene 1: biological functions and molecular mechanism in cancer and beyond.Resistance to Inhibitors of Cholinesterase 3 (Ric-3) Expression Promotes Selective Protein Associations with the Human α7-Nicotinic Acetylcholine Receptor Interactome.Cytoplasmic Metadherin (MTDH) provides survival advantage under conditions of stress by acting as RNA-binding protein.EFEMP1 promotes the migration and invasion of osteosarcoma via MMP-2 with induction by AEG-1 via NF-κB signaling pathway.Metadherin regulation of vascular endothelial growth factor expression is dependent upon the PI3K/Akt pathway in squamous cell carcinoma of the head and neck.Lentivirus-Mediated Knockdown of Astrocyte Elevated Gene-1 Inhibits Growth and Induces Apoptosis through MAPK Pathways in Human Retinoblastoma Cells Profiling and inhibiting reversible palmitoylation Genomic analyses reveal broad impact of miR-137 on genes associated with malignant transformation and neuronal differentiation in glioblastoma cells.AEG-1/MTDH/LYRIC: signaling pathways, downstream genes, interacting proteins, and regulation of tumor angiogenesis.Drug resistance mediated by AEG-1/MTDH/LYRIC.The role of AEG-1/MTDH/LYRIC in the pathogenesis of central nervous system disease Increased expression of metadherin protein predicts worse disease-free and overall survival in laryngeal squamous cell carcinoma.Role of metadherin in estrogen-regulated gene expression.Astrocyte Elevated Gene 1 Interacts with Acetyltransferase p300 and c-Jun To Promote Tumor Aggressiveness.Upregulation of AEG-1 Involves in Schwann Cell Proliferation and Migration After Sciatic Nerve Crush.Knockdown of Astrocyte Elevated Gene-1 Inhibits Activation of Hepatic Stellate Cells.Astrocyte elevated gene-1 mediates glycolysis and tumorigenesis in colorectal carcinoma cells via AMPK signaling.Metadherin confers chemoresistance of cervical cancer cells by inducing autophagy and activating ERK/NF-κB pathway.Astrocyte elevated gene-1 is a novel biomarker of epithelial-mesenchymal transition and progression of hepatocellular carcinoma in two China regions.Astrocyte elevated gene-1 overexpression in hepatocellular carcinoma: an independent prognostic factor AEG-1 associates with metastasis in papillary thyroid cancer through upregulation of MMP2/9.Delivery of miR-375 and doxorubicin hydrochloride by lipid-coated hollow mesoporous silica nanoparticles to overcome multiple drug resistance in hepatocellular carcinoma.Inhibition of Hypoxia Inducible Factor Alpha and Astrocyte-Elevated Gene-1 Mediates Cryptotanshinone Exerted Antitumor Activity in Hypoxic PC-3 Cells.

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Astrocyte elevated gene-1 (AEG-1): A multifunctional regulator of normal and abnormal physiology

http://www.wikidata.org/entity/Q24616987

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2011 nî lūn-bûn

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2011 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2011 թվականի ապրիլին հրատարակված գիտական հոդված

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2011年の論文

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Astrocyte elevated gene-1 (AEG ...... normal and abnormal physiology

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J.PHARMTHERA.2011.01.008

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Pharmacology & Therapeutics

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Byoung Kwon Yoo

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Devanand Sarkar

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Dong Chen

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Luni Emdad

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Paul B Fisher

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Prasanna Santhekadur

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Rachel Gredler

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Zao-zhong Su

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TOK-1, a novel p21Cip1-binding protein that cooperatively enhances p21-dependent inhibitory activity toward CDK2 kinase

Activation of the nuclear factor kappaB pathway by astrocyte elevated gene-1: implications for tumor progression and metastasis

Cloning and characterization of HIV-1-inducible astrocyte elevated gene-1, AEG-1

Rrs1 is involved in endoplasmic reticulum stress response in Huntington disease

3D3/lyric: a novel transmembrane protein of the endoplasmic reticulum and nuclear envelope, which is also present in the nucleolus

Astrocyte elevated gene-1 (AEG-1) is induced by lipopolysaccharide as toll-like receptor 4 (TLR4) ligand and regulates TLR4 signalling

Nuclear LYRIC/AEG-1 interacts with PLZF and relieves PLZF-mediated repression

Molecular basis of nuclear factor-kappaB activation by astrocyte elevated gene-1

Astrocyte elevated gene-1 (AEG-1) functions as an oncogene and regulates angiogenesis

LYRIC/AEG-1 overexpression modulates BCCIPalpha protein levels in prostate tumor cells

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10.1016/J.PHARMTHERA.2011.01.008

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