Renal Ca2+ wasting, hyperabsorption, and reduced bone thickness in mice lacking TRPV5
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Calbindin-D28K dynamically controls TRPV5-mediated Ca2+ transportWNK3 positively regulates epithelial calcium channels TRPV5 and TRPV6 via a kinase-dependent pathwayInternational Union of Basic and Clinical Pharmacology. LXXVI. Current progress in the mammalian TRP ion channel familyRegulation of transient receptor potential channels by the phospholipase C pathwayCalcium-sensing receptor 20 years laterVitamin D, calcium homeostasis and agingThe Control of Calcium Metabolism in Zebrafish (Danio rerio)Klotho: a humeral mediator in CSF and plasma that influences longevity and susceptibility to multiple complex disorders, including depressionMarked disturbance of calcium homeostasis in mice with targeted disruption of the Trpv6 calcium channel geneMolecular mechanisms of calmodulin action on TRPV5 and modulation by parathyroid hormoneTRP channelsMucin-1 Increases Renal TRPV5 Activity In Vitro, and Urinary Level Associates with Calcium Nephrolithiasis in PatientsExcision of Trpv6 gene leads to severe defects in epididymal Ca2+ absorption and male fertility much like single D541A pore mutation.Frequency of rare allelic variation in candidate genes among individuals with low and high urinary calcium excretionExpression and water calcium dependence of calcium transporter isoforms in zebrafish gill mitochondrion-rich cells.Enhanced passive Ca2+ reabsorption and reduced Mg2+ channel abundance explains thiazide-induced hypocalciuria and hypomagnesemia.TRPV-5 mediates a receptor activator of NF-kappaB (RANK) ligand-induced increase in cytosolic Ca2+ in human osteoclasts and down-regulates bone resorption.High dose vitamin D3 attenuates the hypocalciuric effect of thiazide in hypercalciuric rats.The identification of Histidine 712 as a critical residue for constitutive TRPV5 internalization.The epithelial Ca2+ channel TRPV5 is essential for proper osteoclastic bone resorption.Micropuncturing the nephron.Impaired renal calcium absorption in mice lacking calcium channel beta 3 subunits.Direct interaction with Rab11a targets the epithelial Ca2+ channels TRPV5 and TRPV6 to the plasma membrane.Reduced renal calcium excretion in the absence of sclerostin expression: evidence for a novel calcium-regulating bone kidney axis.Down-regulation of intestinal apical calcium entry channel TRPV6 by ubiquitin E3 ligase Nedd4-2.The TRP superfamily of cation channels.The WNKs: atypical protein kinases with pleiotropic actions.WNK4 enhances TRPV5-mediated calcium transport: potential role in hypercalciuria of familial hyperkalemic hypertension caused by gene mutation of WNK4.Autosomal dominant hypercalciuria in a mouse model due to a mutation of the epithelial calcium channel, TRPV5A novel ion channel formed by interaction of TRPML3 with TRPV5.Vitamin D: Metabolism, Molecular Mechanism of Action, and Pleiotropic Effects.WNK4-mediated regulation of renal ion transport proteins.Klotho up-regulates renal calcium channel transient receptor potential vanilloid 5 (TRPV5) by intra- and extracellular N-glycosylation-dependent mechanisms.Calcium signaling in osteoclasts.Effects of vitamin D receptor polymorphisms on urolithiasis risk: a meta-analysisDiuretics, calciuria and secondary hyperparathyroidism in the Chronic Renal Insufficiency Cohort.Calbindin D(9k) knockout mice are indistinguishable from wild-type mice in phenotype and serum calcium level.Adenosine and kidney function: potential implications in patients with heart failure.Intracellular ATP supports TRPV6 activity via lipid kinases and the generation of PtdIns(4,5) P₂.Genetic variants in transient receptor potential cation channel, subfamily M 1 (TRPM1) and their risk of albuminuria-related traits in Mexican Americans.
P2860
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P2860
Renal Ca2+ wasting, hyperabsorption, and reduced bone thickness in mice lacking TRPV5
description
2003 nî lūn-bûn
@nan
2003 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Renal Ca2+ wasting, hyperabsorption, and reduced bone thickness in mice lacking TRPV5
@ast
Renal Ca2+ wasting, hyperabsorption, and reduced bone thickness in mice lacking TRPV5
@en
Renal Ca2+ wasting, hyperabsorption, and reduced bone thickness in mice lacking TRPV5
@nl
type
label
Renal Ca2+ wasting, hyperabsorption, and reduced bone thickness in mice lacking TRPV5
@ast
Renal Ca2+ wasting, hyperabsorption, and reduced bone thickness in mice lacking TRPV5
@en
Renal Ca2+ wasting, hyperabsorption, and reduced bone thickness in mice lacking TRPV5
@nl
prefLabel
Renal Ca2+ wasting, hyperabsorption, and reduced bone thickness in mice lacking TRPV5
@ast
Renal Ca2+ wasting, hyperabsorption, and reduced bone thickness in mice lacking TRPV5
@en
Renal Ca2+ wasting, hyperabsorption, and reduced bone thickness in mice lacking TRPV5
@nl
P2093
P2860
P50
P3181
P1476
Renal Ca2+ wasting, hyperabsorption, and reduced bone thickness in mice lacking TRPV5
@en
P2093
Anne-Marie Mérillat
Annemiete W C M van der Kemp
Bernard C Rossier
Edith Hummler
Ferry F J Kersten
Jan H Waarsing
Joost G J Hoenderop
René J M Bindels
P2860
P304
P3181
P356
10.1172/JCI19826
10.1172/JCI200319826
P407
P577
2003-12-01T00:00:00Z