Inhibitory effect of 2',3'-didehydro-2',3'-dideoxynucleosides on infectivity, cytopathic effects, and replication of human immunodeficiency virus - Wikidata - awgldk - TriplyDB

Inhibitory effect of 2',3'-didehydro-2',3'-dideoxynucleosides on infectivity, cytopathic effects, and replication of human immunodeficiency virus

Inhibitory effect of 2',3'-didehydro-2',3'-dideoxynucleosides on infectivity, cytopathic effects, and replication of human immunodeficiency virus

http://www.wikidata.org/entity/Q24619823

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An Odyssey in antiviral drug development-50 years at the Rega Institute: 1964-2014 Approved Antiviral Drugs over the Past 50 Years Direct comparisons of inhibitor sensitivities of reverse transcriptases from feline and human immunodeficiency viruses Zidovudine-resistant human immunodeficiency virus selected by passage in cell culture Synthesis of pyranoid analogues of the anti-HIV active 3'-deoxy-2',3'-didehydrothymidine (D4T)Anti-human immunodeficiency virus type 1 activity and in vitro toxicity of 2'-deoxy-3'-thiacytidine (BCH-189), a novel heterocyclic nucleoside analog Ribavirin antagonizes inhibitory effects of pyrimidine 2',3'-dideoxynucleosides but enhances inhibitory effects of purine 2',3'-dideoxynucleosides on replication of human immunodeficiency virus in vitro Analysis and prediction of highly effective antiviral peptides based on random forests Anti-human immunodeficiency virus type 1 activity and resistance profile of 2',3'-didehydro-3'-deoxy-4'-ethynylthymidine in vitro Molecular modeling approach to understanding the mode of action of L-nucleosides as antiviral agents Prodrug and antedrug: two diametrical approaches in designing safer drugs.Mechanisms of nucleoside analog antiviral activity and resistance during human immunodeficiency virus reverse transcription Mutants of feline immunodeficiency virus resistant to 2',3'-dideoxy-2',3'-didehydrothymidine.Development of inhibitors of reverse transcriptase and protease as therapeutics against HIV infection.Susceptibilities of zidovudine-susceptible and -resistant human immunodeficiency virus isolates to antiviral agents determined by using a quantitative plaque reduction assay.Pharmacokinetics of 3'-fluoro-3'-deoxythymidine and 3'-deoxy-2',3'-didehydrothymidine in rhesus monkeys.Antiviral therapy for human immunodeficiency virus infections Kinetics and inhibition of reverse transcriptase from human and simian immunodeficiency viruses.Comparison of the phosphorylation of 4'-ethynyl 2',3'-dihydro-3'-deoxythymidine with that of other anti-human immunodeficiency virus thymidine analogs.Mechanism of inhibition of human immunodeficiency virus type 1 reverse transcriptase by a stavudine analogue, 4'-ethynyl stavudine triphosphate Pharmacokinetics of 3'-fluoro-3'-deoxythymidine and 3'-deoxy-2',3'-didehydrothymidine in rats.The discovery of antiviral agents: ten different compounds, ten different stories.Impact of novel human immunodeficiency virus type 1 reverse transcriptase mutations P119S and T165A on 4'-ethynylthymidine analog resistance profile.Novel 4'-substituted stavudine analog with improved anti-human immunodeficiency virus activity and decreased cytotoxicity.Clinical applications of 3'-azido-2',3'-dideoxythymidine (AZT) and related dideoxynucleosides.Curious discoveries in antiviral drug development: the role of serendipity.Synthesis of novel L-N-MCd4T as a potent anti-HIV agent.Synthesis and anti-HIV activity of [ddN]-[ddN] dimers and benzimidazole nucleoside dimers.In vitro drug combination of 1-beta-D-arabinofuranosyl-E-5-(2-bromovinyl)uracil with anti-human immunodeficiency virus or anticancer nucleosides.Synthesis and biological activity of chloroethyl pyrimidine nucleosides.Cytocidal effect of tumor necrosis factor on cells chronically infected with human immunodeficiency virus (HIV): enhancement of HIV replication.Rapid screening method with a cell multisizer for inhibitors of human immunodeficiency virus-induced cell fusion in vitro.Cellular pharmacology of 2',3'-dideoxy-2',3'-didehydrothymidine, a nucleoside analog active against human immunodeficiency virus.Isothiazole derivatives as novel HIV replication inhibitors.Synthesis, structural characterization and biological evaluation of 4'-C-methyl- and phenyl-dioxolane pyrimidine and purine nucleosides.Stavudine:pharmacology,clinical use and future role.Quantitative assay for testing susceptibility of HIV isolates to zidovudine and sCD4 (178)-PE40.Structural and energetic properties of the potential HIV-1 reverse transcriptase inhibitors d4A and d4G: a comprehensive theoretical investigation.The history of antiretrovirals: key discoveries over the past 25 years.Complete conformational space of the potential HIV-1 reverse transcriptase inhibitors d4U and d4C. A quantum chemical study

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Inhibitory effect of 2',3'-didehydro-2',3'-dideoxynucleosides on infectivity, cytopathic effects, and replication of human immunodeficiency virus

http://www.wikidata.org/entity/Q24619823

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1987 nî lūn-bûn

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1987 թուականի Յունիսին հրատարակուած գիտական յօդուած

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1987 թվականի հունիսին հրատարակված գիտական հոդված

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1987年の論文

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1987年学术文章

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1987年学术文章

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1987年学术文章

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1987年学术文章

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Antimicrobial Agents and Chemotherapy

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A Matsuda

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H Nakashima

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N Yamamoto

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P2860

3'-Azido-3'-deoxythymidine (BW A509U): an antiviral agent that inhibits the infectivity and cytopathic effect of human T-lymphotropic virus type III/lymphadenopathy-associated virus in vitro

Inhibition of human T-cell lymphotropic virus type III in vitro by phosphonoformate

Inhibition of the in vitro infectivity and cytopathic effect of human T-lymphotrophic virus type III/lymphadenopathy-associated virus (HTLV-III/LAV) by 2',3'-dideoxynucleosides

Infection of HTLV-III/LAV in HTLV-I-carrying cells MT-2 and MT-4 and application in a plaque assay

Nucleosides. IX. The formation of 2',2'-unsaturated pyrimidine nucleosides via a novel beta-elimination reaction.

Administration of 3'-azido-3'-deoxythymidine, an inhibitor of HTLV-III/LAV replication, to patients with AIDS or AIDS-related complex.

Effect of 2',3'-dideoxythymidine-5'-triphosphate on HeLa cell in vitro DNA synthesis: evidence that DNA polymerase alpha is the only polymerase required for cellular DNA replication

Suramin protection of T cells in vitro against infectivity and cytopathic effect of HTLV-III.

Inhibition of the activity of DNA polymerase alpha by 2',3'-dideoxythymidine 5'-triphosphate.

Inhibition of replication and cytopathic effect of human T cell lymphotropic virus type III/lymphadenopathy-associated virus by 3'-azido-3'-deoxythymidine in vitro

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907-10

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10.1128/AAC.31.6.907

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6

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31

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3039911

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284209

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