Vaccine-induced monoclonal antibodies targeting circumsporozoite protein prevent Plasmodium falciparum infection
about
Circumsporozoite protein as a potential target for antimalarialsAnimal models for the study of HCVIdentification of Novel Pre-Erythrocytic Malaria Antigen Candidates for Combination Vaccines with Circumsporozoite ProteinConformational dynamics and antigenicity in the disordered malaria antigen merozoite surface protein 2Insights into the Immunological Properties of Intrinsically Disordered Malaria Proteins Using Proteome Scale Predictions.Of men in mice: the success and promise of humanized mouse models for human malaria parasite infections.Development of a Novel Virus-Like Particle Vaccine Platform That Mimics the Immature Form of Alphavirus.Sporozoite immunization of human volunteers under chemoprophylaxis induces functional antibodies against pre-erythrocytic stages of Plasmodium falciparum.Vectored antibody gene delivery protects against Plasmodium falciparum sporozoite challenge in miceImmunization of mice with live-attenuated late liver stage-arresting Plasmodium yoelii parasites generates protective antibody responses to preerythrocytic stages of malariaA combined analysis of immunogenicity, antibody kinetics and vaccine efficacy from phase 2 trials of the RTS,S malaria vaccine.Plasmodium berghei circumsporozoite protein encapsulated in oligomannose-coated liposomes confers protection against sporozoite infection in mice.Antibody and B cell responses to Plasmodium sporozoites.Malaria Parasite Liver Infection and Exoerythrocytic Biology.Memory B-cell and antibody responses induced by Plasmodium falciparum sporozoite immunization.Avidity of anti-circumsporozoite antibodies following vaccination with RTS,S/AS01E in young children.A PfRH5-based vaccine is efficacious against heterologous strain blood-stage Plasmodium falciparum infection in aotus monkeys.Evaluation of the efficacy of ChAd63-MVA vectored vaccines expressing circumsporozoite protein and ME-TRAP against controlled human malaria infection in malaria-naive individuals.Structural basis for epitope masking and strain specificity of a conserved epitope in an intrinsically disordered malaria vaccine candidate.Flow Cytometry Based Detection and Isolation of Plasmodium falciparum Liver Stages In VitroLongitudinal analysis of Plasmodium sporozoite motility in the dermis reveals component of blood vessel recognitionA monoclonal antibody-based immunoassay to measure the antibody response against the repeat region of the circumsporozoite protein of Plasmodium falciparum.Towards a Humanized Mouse Model of Liver Stage Malaria Using Ectopic Artificial Livers.Correlates of protective immunity following whole sporozoite vaccination against malaria.New insight-guided approaches to detect, cure, prevent and eliminate malaria.An expanding toolkit for preclinical pre-erythrocytic malaria vaccine development: bridging traditional mouse malaria models and human trials.A whole-killed, blood-stage lysate vaccine protects against the malaria liver stage.Protective immunity differs between routes of administration of attenuated malaria parasites independent of parasite liver load.A Prime/Boost PfCS14KM/MVA-sPfCSM Vaccination Protocol Generates Robust CD8+ T Cell and Antibody Responses to Plasmodium falciparum Circumsporozoite Protein and Protects Mice against Malaria.Successful Engraftment of Human Hepatocytes in uPA-SCID and FRG(®) KO Mice.T-dependent B cell responses to Plasmodium induce antibodies that form a high-avidity multivalent complex with the circumsporozoite protein.Anti-CD81 but not anti-SR-BI blocks Plasmodium falciparum liver infection in a humanized mouse model.Humanized mouse models infected with human Plasmodium species for antimalarial drug discovery.Humoral protection against mosquito bite-transmitted Plasmodium falciparum infection in humanized mice.Natural Parasite Exposure Induces Protective Human Anti-Malarial Antibodies.Rare PfCSP C-terminal antibodies induced by live sporozoite vaccination are ineffective against malaria infection.Malaria DNA vaccine gp96NTD-CSP elicits both CSP-specific antibody and CD8(+) T cell response.A human monoclonal antibody prevents malaria infection by targeting a new site of vulnerability on the parasite.Human antibodies activate complement against Plasmodium falciparum sporozoites, and are associated with protection against malaria in children.Humanized Mouse Models for the Study of Human Malaria Parasite Biology, Pathogenesis, and Immunity.
P2860
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P2860
Vaccine-induced monoclonal antibodies targeting circumsporozoite protein prevent Plasmodium falciparum infection
description
2014 nî lūn-bûn
@nan
2014 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Vaccine-induced monoclonal ant ...... lasmodium falciparum infection
@ast
Vaccine-induced monoclonal ant ...... lasmodium falciparum infection
@en
Vaccine-induced monoclonal ant ...... lasmodium falciparum infection
@nl
type
label
Vaccine-induced monoclonal ant ...... lasmodium falciparum infection
@ast
Vaccine-induced monoclonal ant ...... lasmodium falciparum infection
@en
Vaccine-induced monoclonal ant ...... lasmodium falciparum infection
@nl
prefLabel
Vaccine-induced monoclonal ant ...... lasmodium falciparum infection
@ast
Vaccine-induced monoclonal ant ...... lasmodium falciparum infection
@en
Vaccine-induced monoclonal ant ...... lasmodium falciparum infection
@nl
P2093
P2860
P50
P3181
P356
P1476
Vaccine-induced monoclonal ant ...... lasmodium falciparum infection
@en
P2093
Cornelus C Hermsen
Eva Van Braeckel
Karin E Weening
P2860
P3181
P356
10.1172/JCI70349
P407
P577
2014-01-01T00:00:00Z