Comprehensive molecular characterization of human colon and rectal cancer
about
Identification of druggable cancer driver genes amplified across TCGA datasetsStructural basis for activation and non-canonical catalysis of the Rap GTPase activating protein domain of plexinMSH3 mismatch repair protein regulates sensitivity to cytotoxic drugs and a histone deacetylase inhibitor in human colon carcinoma cellsDNA methylation changes in genes frequently mutated in sporadic colorectal cancer and in the DNA repair and Wnt/β-catenin signaling pathway genesIntegrative annotation of variants from 1092 humans: application to cancer genomicsEpigenetic field defects in progression to cancerCancer genome landscapesMolecular pathological epidemiology of epigenetics: emerging integrative science to analyze environment, host, and diseaseOpposing activities of the Ras and Hippo pathways converge on regulation of YAP protein turnoverβ-Catenin-driven cancers require a YAP1 transcriptional complex for survival and tumorigenesisAdenomatous polyposis coli (APC) membrane recruitment 3, a member of the APC membrane recruitment family of APC-binding proteins, is a positive regulator of Wnt-β-catenin signallingGermline ETV6 mutations in familial thrombocytopenia and hematologic malignancyPHLPP is a negative regulator of RAF1, which reduces colorectal cancer cell motility and prevents tumor progression in miceAmplification of the MET receptor drives resistance to anti-EGFR therapies in colorectal cancerEnabling transparent and collaborative computational analysis of 12 tumor types within The Cancer Genome AtlasNCG 4.0: the network of cancer genes in the era of massive mutational screenings of cancer genomesEra of universal testing of microsatellite instability in colorectal cancerThe Cancer Genome Atlas Pan-Cancer analysis projectMutational heterogeneity in cancer and the search for new cancer-associated genesGermline mutations affecting the proofreading domains of POLE and POLD1 predispose to colorectal adenomas and carcinomasTowards tumor immunodiagnosticsNew trends in molecular and cellular biomarker discovery for colorectal cancerGenomic diversity of colorectal cancer: Changing landscape and emerging targetsCurrent targeted therapies in the treatment of advanced colorectal cancer: a reviewTCF/LEF Transcription Factors: An Update from the Internet ResourcesMolecular pathological classification of colorectal cancerMolecular profiles to biology and pathways: a systems biology approachThe value of genomics in dissecting the RAS-network and in guiding therapeutics for RAS-driven cancersIncreasing incidence of colon cancer in patients <50 years old: a new entity?Frizzled7: A Promising Achilles' Heel for Targeting the Wnt Receptor Complex to Treat CancerThe Role of Chemokines in Promoting Colorectal Cancer Invasion/MetastasisPractical aspects of NGS-based pathways analysis for personalized cancer science and medicineAdvances in targeted and immunobased therapies for colorectal cancer in the genomic eraEpigenetic modulators, modifiers and mediators in cancer aetiology and progressionImmunological Landscape and Clinical Management of Rectal CancerIntegrating the molecular background of targeted therapy and immunotherapy in lung cancer: a way to explore the impact of mutational landscape on tumor immunogenicityRole of microRNA-7 in digestive system malignancyProfile of panitumumab as first-line treatment in patients with wild-type KRAS metastatic colorectal cancerTumor evolution and intratumor heterogeneity in colorectal carcinoma: insights from comparative genomic profiling of primary tumors and matched metastasesNew therapeutic strategies for BRAF mutant colorectal cancers
P2860
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P2860
Comprehensive molecular characterization of human colon and rectal cancer
description
2012 nî lūn-bûn
@nan
2012 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Comprehensive molecular characterization of human colon and rectal cancer
@ast
Comprehensive molecular characterization of human colon and rectal cancer
@en
Comprehensive molecular characterization of human colon and rectal cancer
@nl
type
label
Comprehensive molecular characterization of human colon and rectal cancer
@ast
Comprehensive molecular characterization of human colon and rectal cancer
@en
Comprehensive molecular characterization of human colon and rectal cancer
@nl
prefLabel
Comprehensive molecular characterization of human colon and rectal cancer
@ast
Comprehensive molecular characterization of human colon and rectal cancer
@en
Comprehensive molecular characterization of human colon and rectal cancer
@nl
P2860
P3181
P356
P1433
P1476
Comprehensive molecular characterization of human colon and rectal cancer
@en
P2860
P2888
P3181
P356
10.1038/NATURE11252
P407
P577
2012-07-19T00:00:00Z
P5875
P6179
1010619765