Akt suppresses androgen-induced apoptosis by phosphorylating and inhibiting androgen receptor - Wikidata - awgldk - TriplyDB

Akt suppresses androgen-induced apoptosis by phosphorylating and inhibiting androgen receptor

Akt suppresses androgen-induced apoptosis by phosphorylating and inhibiting androgen receptor

http://www.wikidata.org/entity/Q24631156

about

Identification of human male germ cell-associated kinase, a kinase transcriptionally activated by androgen in prostate cancer cells Akt phosphorylates and suppresses the transactivation of retinoic acid receptor alpha The estrogen-responsive B box protein is a novel regulator of the retinoid signal Structure and function of steroid receptor AF1 transactivation domains: induction of active conformations Phosphorylation-dependent regulation of cytosolic localization and oncogenic function of Skp2 by Akt/PKB Androgen Receptor Structure, Function and Biology: From Bench to Bedside Persistent androgen receptor addiction in castration-resistant prostate cancer Developing treatment for spinal and bulbar muscular atrophy ArgBP2gamma interacts with Akt and p21-activated kinase-1 and promotes cell survival Suppression of androgen receptor-mediated transactivation and cell growth by the glycogen synthase kinase 3 beta in prostate cells p21-Activated kinase 6 (PAK6) inhibits prostate cancer growth via phosphorylation of androgen receptor and tumorigenic E3 ligase murine double minute-2 (Mdm2)PTEN and GSK3beta: key regulators of progression to androgen-independent prostate cancer Targeted therapy for advanced prostate cancer: inhibition of the PI3K/Akt/mTOR pathway Activation of AMP-activated protein kinase by 3,3'-Diindolylmethane (DIM) is associated with human prostate cancer cell death in vitro and in vivo Phosphorylation-dependent ubiquitylation and degradation of androgen receptor by Akt require Mdm2 E3 ligase Novel Imidazopyridine Derivatives Possess Anti-Tumor Effect on Human Castration-Resistant Prostate Cancer Cells αvβ6 Integrin Promotes Castrate-Resistant Prostate Cancer through JNK1-Mediated Activation of Androgen Receptor.Androgen receptor phosphorylation. Regulation and identification of the phosphorylation sites.Serine 421 regulates mutant huntingtin toxicity and clearance in mice.Androgen receptor phosphorylation: biological context and functional consequences.Simian virus 40 small t antigen mediates conformation-dependent transfer of protein phosphatase 2A onto the androgen receptor.Restoration of PTEN expression alters the sensitivity of prostate cancer cells to EGFR inhibitors.Suppression of androgen receptor transactivation by Pyk2 via interaction and phosphorylation of the ARA55 coregulator.Survey of phosphorylation near drug binding sites in the Protein Data Bank (PDB) and their effects.A putative biomarker signature for clinically effective AKT inhibition: correlation of in vitro, in vivo and clinical data identifies the importance of modulation of the mTORC1 pathway.Risk of hormone escape in a human prostate cancer model depends on therapy modalities and can be reduced by tyrosine kinase inhibitors Androgen receptor targets NFkappaB and TSP1 to suppress prostate tumor growth in vivo.Kinase modulation of androgen receptor signaling: implications for prostate cancer Androgen receptor as a driver of therapeutic resistance in advanced prostate cancer.Identification of androgen receptor phosphorylation in the primate ovary in vivo.Vitamin E succinate inhibits the function of androgen receptor and the expression of prostate-specific antigen in prostate cancer cells 1,4-phenylenebis(methylene)selenocyanate, but not selenomethionine, inhibits androgen receptor and Akt signaling in human prostate cancer cells.Expression of the Androgen Receptor, pAkt, and pPTEN in Breast Cancer and Their Potential in Prognostication.INPP4B: the new kid on the PI3K block.APPL suppresses androgen receptor transactivation via potentiating Akt activity.Phosphorylation and activation of androgen receptor by Aurora-A Prolonging hormone sensitivity in prostate cancer xenografts through dual inhibition of AR and mTOR.Acetylation of androgen receptor enhances coactivator binding and promotes prostate cancer cell growth.The androgen receptor acetylation site regulates cAMP and AKT but not ERK-induced activity.Androgen receptor signaling and mutations in prostate cancer

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P2860

Akt suppresses androgen-induced apoptosis by phosphorylating and inhibiting androgen receptor

http://www.wikidata.org/entity/Q24631156

description

2001 nî lūn-bûn

@nan

2001 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

2001 թվականի հունիսին հրատարակված գիտական հոդված

@hy

2001年の論文

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2001年論文

@yue

2001年論文

@zh-hant

2001年論文

@zh-hk

2001年論文

@zh-mo

2001年論文

@zh-tw

2001年论文

@wuu

name

Akt suppresses androgen-induce ...... d inhibiting androgen receptor

@ast

Akt suppresses androgen-induce ...... d inhibiting androgen receptor

@en

Akt suppresses androgen-induce ...... d inhibiting androgen receptor

@nl

type

label

Akt suppresses androgen-induce ...... d inhibiting androgen receptor

@ast

Akt suppresses androgen-induce ...... d inhibiting androgen receptor

@en

Akt suppresses androgen-induce ...... d inhibiting androgen receptor

@nl

prefLabel

Akt suppresses androgen-induce ...... d inhibiting androgen receptor

@ast

Akt suppresses androgen-induce ...... d inhibiting androgen receptor

@en

Akt suppresses androgen-induce ...... d inhibiting androgen receptor

@nl

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P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

Akt suppresses androgen-induce ...... d inhibiting androgen receptor

@en

P2093

C Chang

http://www.w3.org/2001/XMLSchema#string

H K Lin

http://www.w3.org/2001/XMLSchema#string

H Y Kang

http://www.w3.org/2001/XMLSchema#string

S Yeh

http://www.w3.org/2001/XMLSchema#string

P2860

Cloning and characterization of human prostate coactivator ARA54, a novel protein that associates with the androgen receptor

Cloning and characterization of a specific coactivator, ARA70, for the androgen receptor in human prostate cells

Requirement of ErbB2 for signalling by interleukin-6 in prostate carcinoma cells

Increase of androgen-induced cell death and androgen receptor transactivation by BRCA1 in prostate cancer cells

From HER2/Neu signal cascade to androgen receptor and its coactivators: a novel pathway by induction of androgen target genes through MAP kinase in prostate cancer cells

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

Molecular cloning of human and rat complementary DNA encoding androgen receptors

AKT/PKB and other D3 phosphoinositide-regulated kinases: kinase activation by phosphoinositide-dependent phosphorylation

Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt

Regulation of cell death protease caspase-9 by phosphorylation

P304

7200-5

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scholarly article

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4541499

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10.1073/PNAS.121173298

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13

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98

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2001-06-19T00:00:00Z

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11936194

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P698

11404460

http://www.w3.org/2001/XMLSchema#string

P921

apoptotic process

phosphorylation

P932

34646

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