Human aneuploidy: mechanisms and new insights into an age-old problem - Wikidata - awgldk - TriplyDB

Human aneuploidy: mechanisms and new insights into an age-old problem

Human aneuploidy: mechanisms and new insights into an age-old problem

http://www.wikidata.org/entity/Q24631178

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A quality control mechanism linking meiotic success to release of ascospores Single cell genomics: advances and future perspectives Metabolic heterogeneity during preimplantation development: the missing link?Oocyte Maturation and Development Oocyte development, meiosis and aneuploidy The spindle checkpoint and chromosome segregation in meiosis Yeast: a simple model system to study complex phenomena of aneuploidy Sister chromatid segregation in meiosis II: deprotection through phosphorylation Ovarian adult stem cells: hope or pitfall?Live imaging RNAi screen reveals genes essential for meiosis in mammalian oocytes.Reduced life- and healthspan in mice carrying a mono-allelic BubR1 MVA mutation TRAIP is involved in chromosome alignment and SAC regulation in mouse oocyte meiosis Pre-implantation genetic testing in ART: who will benefit and what is the evidence?Meiosis and maternal aging: insights from aneuploid oocytes and trisomy births Lack of dosage compensation accompanies the arrested stage of sex chromosome evolution in ostriches Increased frequency of aneuploidy in long-lived spermatozoa Sirt2 functions in spindle organization and chromosome alignment in mouse oocyte meiosis Genome-wide maps of recombination and chromosome segregation in human oocytes and embryos show selection for maternal recombination rates Properties and rates of germline mutations in humans An old culprit but a new story: bisphenol A and “NextGen” bisphenols Mutant Cohesin in Premature Ovarian Failure Modulation of Aneuploidy in Leishmania donovani during Adaptation to Different In Vitro and In Vivo Environments and Its Impact on Gene Expression.Premature dyad separation in meiosis II is the major segregation error with maternal age in mouse oocytes Bivalent separation into univalents precedes age-related meiosis I errors in oocytes.Loss of Centromere Cohesion in Aneuploid Human Oocytes Correlates with Decreased Kinetochore Localization of the Sac Proteins Bub1 and Bubr1 Night Monkey Hybrids Exhibit De Novo Genomic and Karyotypic Alterations: The First Such Case in Primates Kinetochore microtubule establishment is defective in oocytes from aged mice New tools for embryo selection: comprehensive chromosome screening by array comparative genomic hybridization.Zfy genes are required for efficient meiotic sex chromosome inactivation (MSCI) in spermatocytes Age-related increase in aneuploidy and alteration of gene expression in mouse first polar bodies Early embryo mortality in natural human reproduction: What the data say.Maternal age-dependent APC/C-mediated decrease in securin causes premature sister chromatid separation in meiosis II.Linking chromosome duplication and segregation via sister chromatid cohesion TroX: a new method to learn about the genesis of aneuploidy from trisomic products of conception.Examining variation in recombination levels in the human female: a test of the production-line hypothesis Reduced ability to recover from spindle disruption and loss of kinetochore spindle assembly checkpoint proteins in oocytes from aged mice.The association of low socioeconomic status and the risk of having a child with Down syndrome: a report from the National Down Syndrome Project.Quantitative proteomic analysis reveals posttranslational responses to aneuploidy in yeast.Birth defects and congenital health risks in children conceived through assisted reproduction technology (ART): a meeting report Rejuvenation of meiotic cohesion in oocytes during prophase I is required for chiasma maintenance and accurate chromosome segregation.

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Human aneuploidy: mechanisms and new insights into an age-old problem

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2012 nî lūn-bûn

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Human aneuploidy: mechanisms and new insights into an age-old problem

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Nature Reviews Genetics

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Human aneuploidy: mechanisms and new insights into an age-old problem

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Patricia A Hunt

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So I Nagaoka

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Terry J Hassold

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P2860

Oocyte formation by mitotically active germ cells purified from ovaries of reproductive-age women

Recombination and maternal age-dependent nondisjunction: molecular studies of trisomy 16

Cdc20 is critical for meiosis I and fertility of female mice

The spindle-assembly checkpoint in space and time

The G2-phase DNA-damage checkpoint

Association between spindle assembly checkpoint expression and maternal age in human oocytes

In vitro-differentiated embryonic stem cells give rise to male gametes that can generate offspring mice

Bisphenol A impairs the double-strand break repair machinery in the germline and causes chromosome abnormalities.

Bisphenol A exposure reduces the estradiol response to gonadotropin stimulation during in vitro fertilization

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10.1038/NRG3245

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