Histone deacetylases mediate the silencing of miR-15a, miR-16, and miR-29b in chronic lymphocytic leukemia - Wikidata - awgldk - TriplyDB

Histone deacetylases mediate the silencing of miR-15a, miR-16, and miR-29b in chronic lymphocytic leukemia

Histone deacetylases mediate the silencing of miR-15a, miR-16, and miR-29b in chronic lymphocytic leukemia

http://www.wikidata.org/entity/Q24633394

about

Clinical significance of microRNAs in chronic and acute human leukemia Know the enemy as well as the weapons in hand: the aberrant death pathways and therapeutic agents in chronic lymphocytic leukemia The role of miR-29b in cancer: regulation, function, and signaling MicroRNA-mediated autophagic signaling networks and cancer chemoresistance The two faces of miR-29 MicroRNA-regulated pathways in hematological malignancies: how to avoid cells playing out of tune The biology and clinical significance of acquired genomic copy number aberrations and recurrent gene mutations in chronic lymphocytic leukemia MicroRNAs in B-cell lymphomas: how a complex biology gets more complex MicroRNAs and B cell receptor signaling in chronic lymphocytic leukemia The role of epigenetic mechanisms and processes in autoimmune disorders Endoplasmic reticulum stress plays a pivotal role in cell death mediated by the pan-deacetylase inhibitor panobinostat in human hepatocellular cancer cells.Genetic abnormalities in chronic lymphocytic leukemia: where we are and where we go HDAC 1/4-mediated silencing of microRNA-200b promotes chemoresistance in human lung adenocarcinoma cells.MicroRNA-29a promotion of nephrin acetylation ameliorates hyperglycemia-induced podocyte dysfunction.Histone deacetylase inhibitor (HDACI) mechanisms of action: emerging insights.miRNAs and cancer: an epigenetics view.Epigenetic alteration and microRNA dysregulation in cancer Inhibition of DNA methyltransferase activity and expression by treatment with the pan-deacetylase inhibitor panobinostat in hepatocellular carcinoma cell lines.Class II HDAC inhibition hampers hepatic stellate cell activation by induction of microRNA-29 E-cadherin gene re-expression in chronic lymphocytic leukemia cells by HDAC inhibitors.Epigenetic upregulation of lncRNAs at 13q14.3 in leukemia is linked to the In Cis downregulation of a gene cluster that targets NF-kB.Growth-promoting role of the miR-106a~363 cluster in Ewing sarcoma.Role of microRNAs on therapy resistance in Non-Hodgkin's lymphoma.miR-29b and miR-29c are involved in Toll-like receptor control of glucocorticoid-induced apoptosis in human plasmacytoid dendritic cells Targeting of YAP1 by microRNA-15a and microRNA-16-1 exerts tumor suppressor function in gastric adenocarcinoma.Alterations in the mir-15a/16-1 Loci Impairs Its Processing and Augments B-1 Expansion in De Novo Mouse Model of Chronic Lymphocytic Leukemia (CLL)A unique histone deacetylase inhibitor alters microRNA expression and signal transduction in chemoresistant ovarian cancer cells HDACs Regulate miR-133a Expression in Pressure Overload-Induced Cardiac Fibrosis.MicroRNAs and Glucocorticoid-Induced Apoptosis in Lymphoid Malignancies Efficacy of Combined Histone Deacetylase and Checkpoint Kinase Inhibition in a Preclinical Model of Human Burkitt Lymphoma.Mechanisms of epigenetic deregulation in lymphoid neoplasms.MiR-29b suppresses the proliferation and migration of osteosarcoma cells by targeting CDK6.Chronic lymphocytic leukemia: molecular heterogeneity revealed by high-throughput genomics Ablation of MCL1 expression by virally induced microRNA-29 reverses chemoresistance in human osteosarcomas.HDAC Inhibition Induces MicroRNA-182, which Targets RAD51 and Impairs HR Repair to Sensitize Cells to Sapacitabine in Acute Myelogenous Leukemia Loss of p53 and altered miR15-a/16-1MCL-1 pathway in CLL: insights from TCL1-Tg:p53(-/-) mouse model and primary human leukemia cells.MicroRNAs and PIWI-interacting RNAs in oncology.Hsa-miR-15a and Hsa-miR-16-1 expression is not related to proliferation centers abundance and other prognostic factors in chronic lymphocytic leukemia.Regulation of microRNAs by epigenetics and their interplay involved in cancer.Macro-role of microRNA in gastric cancer.

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P2860

Histone deacetylases mediate the silencing of miR-15a, miR-16, and miR-29b in chronic lymphocytic leukemia

http://www.wikidata.org/entity/Q24633394

description

2012 nî lūn-bûn

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2012 թուականի Փետրուարին հրատարակուած գիտական յօդուած

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2012 թվականի փետրվարին հրատարակված գիտական հոդված

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年论文

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name

Histone deacetylases mediate t ...... n chronic lymphocytic leukemia

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Histone deacetylases mediate t ...... n chronic lymphocytic leukemia

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Histone deacetylases mediate t ...... n chronic lymphocytic leukemia

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type

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Histone deacetylases mediate t ...... n chronic lymphocytic leukemia

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Histone deacetylases mediate t ...... n chronic lymphocytic leukemia

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Histone deacetylases mediate t ...... n chronic lymphocytic leukemia

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prefLabel

Histone deacetylases mediate t ...... n chronic lymphocytic leukemia

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Histone deacetylases mediate t ...... n chronic lymphocytic leukemia

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Histone deacetylases mediate t ...... n chronic lymphocytic leukemia

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Chaomei Liu

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Deepa Sampath

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Karthik Vasan

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Melanie Sulda

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Vinay K Puduvalli

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P2860

miR-15 and miR-16 induce apoptosis by targeting BCL2

Frequent deletions and down-regulation of micro- RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia

MicroRNA profiling reveals distinct signatures in B cell chronic lymphocytic leukemias

Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs

Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers

MiR-15a and miR-16-1 cluster functions in human leukemia

Abnormal microRNA-16 locus with synteny to human 13q14 linked to CLL in NZB mice

Transcriptional repression mediated by the human polycomb-group protein EED involves histone deacetylation

DLEU2, frequently deleted in malignancy, functions as a critical host gene of the cell cycle inhibitory microRNAs miR-15a and miR-16-1

Causes and consequences of microRNA dysregulation in cancer

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1162-72

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341981

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10.1182/BLOOD-2011-05-351510

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5

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119

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William G Wierda

Michael J. Keating

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2012-02-02T00:00:00Z

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22096249

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3277352

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