Thrombospondin-1 signaling through CD47 inhibits self-renewal by regulating c-Myc and other stem cell transcription factors - Wikidata - awgldk - TriplyDB

Thrombospondin-1 signaling through CD47 inhibits self-renewal by regulating c-Myc and other stem cell transcription factors

Thrombospondin-1 signaling through CD47 inhibits self-renewal by regulating c-Myc and other stem cell transcription factors

http://www.wikidata.org/entity/Q24633525

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CD47 agonist peptides induce programmed cell death in refractory chronic lymphocytic leukemia B cells via PLCγ1 activation: evidence from mice and humans CD47 signaling regulates the immunosuppressive activity of VEGF in T cells.Adipose-derived stromal vascular fraction cells isolated from old animals exhibit reduced capacity to support the formation of microvascular networks.Thrombospondin-1 and CD47 signaling regulate healing of thermal injury in mice.Revisiting the matricellular concept.Therapeutic targeting of the thrombospondin-1 receptor CD47 to treat liver cancer.Thrombospondin-1 in a Murine Model of Colorectal Carcinogenesis.CD47 Receptor Globally Regulates Metabolic Pathways That Control Resistance to Ionizing Radiation A fully human anti-CD47 blocking antibody with therapeutic potential for cancer Transcriptional and Post-Transcriptional Regulation of Thrombospondin-1 Expression: A Computational Model.Of Cytometry, Stem Cells and Fountain of Youth.Secreted Thrombospondin-1 Regulates Macrophage Interleukin-1β Production and Activation through CD47.CD47 signaling pathways controlling cellular differentiation and responses to stress.Thrombospondin-1 might be a therapeutic target to suppress RB cells by regulating the DNA double-strand breaks repair.A function-blocking CD47 antibody suppresses stem cell and EGF signaling in triple-negative breast cancer.Dietary fat overcomes the protective activity of thrombospondin-1 signaling in the Apc(Min/+) model of colon cancer.The role of circulating thrombospondin-1 in patients with precapillary pulmonary hypertension Determination of mesenchymal stem cell fate by pigment epithelium-derived factor (PEDF) results in increased adiposity and reduced bone mineral content.Regulation of soluble guanylate cyclase by matricellular thrombospondins: implications for blood flow.Thrombospondin-1 in urological cancer: pathological role, clinical significance, and therapeutic prospects.Cancer stem cells and tumor-associated macrophages: a roadmap for multitargeting strategies.Regulation of cellular redox signaling by matricellular proteins in vascular biology, immunology, and cancer MYC regulates the antitumor immune response through CD47 and PD-L1 Divergent modulation of normal and neoplastic stem cells by thrombospondin-1 and CD47 signaling.Environmental preconditioning rejuvenates adult stem cells' proliferation and chondrogenic potential.Photodynamic therapy-mediated cancer vaccination enhances stem-like phenotype and immune escape, which can be blocked by thrombospondin-1 signaling through CD47 receptor protein.Thrombospondin-1 signaling through CD47 inhibits cell cycle progression and induces senescence in endothelial cells.The matricellular protein TSP1 promotes human and mouse endothelial cell senescence through CD47 and Nox1.Alteration in cellular turnover and progenitor cell population in lacrimal glands from thrombospondin 1-/- mice, a model of dry eye.A function-blocking CD47 antibody modulates extracellular vesicle-mediated intercellular signaling between breast carcinoma cells and endothelial cells.Deficits in cerebellar granule cell development and social interactions in CD47 knockout mice.Matricellular TSP-1 as a target of interest for impeding melanoma spreading: towards a therapeutic use for TAX2 peptide.Thrombospondin-targeting TAX2 peptide impairs tumor growth in preclinical mouse models of childhood neuroblastoma.TSP1-CD47 signaling is upregulated in clinical pulmonary hypertension and contributes to pulmonary arterial vasculopathy and dysfunction.Computer Simulation of TSP1 Inhibition of VEGF-Akt-eNOS: An Angiogenesis Triple Threat.Intervenolin suppresses gastric cancer cell growth through the induction of TSP-1 secretion from fibroblast-like stromal cells

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Thrombospondin-1 signaling through CD47 inhibits self-renewal by regulating c-Myc and other stem cell transcription factors

http://www.wikidata.org/entity/Q24633525

description

2013 nî lūn-bûn

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2013 թուականի Յունուարին հրատարակուած գիտական յօդուած

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2013年の論文

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Scientific Reports

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Thrombospondin-1 signaling thr ...... tem cell transcription factors

@en

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Abdel G Elkahloun

http://www.w3.org/2001/XMLSchema#string

Alina Nicolae

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Chengyu Liu

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David D Roberts

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David Levens

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David R Soto-Pantoja

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Erica V Stein

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Jeffrey S Isenberg

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Michael L Pendrak

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Satya P Singh

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Rapid and highly efficient generation of induced pluripotent stem cells from human umbilical vein endothelial cells

Loss of Pten causes tumor initiation following differentiation of murine pluripotent stem cells due to failed repression of Nanog

Isolation and characterization of CD47 glycoprotein: a multispanning membrane protein which is the same as integrin-associated protein (IAP) and the ovarian tumour marker OA3

myc maintains embryonic stem cell pluripotency and self-renewal

The CD47-signal regulatory protein alpha (SIRPa) interaction is a therapeutic target for human solid tumors

The N-terminal domain of c-Myc associates with alpha-tubulin and microtubules in vivo and in vitro

Identification, molecular characterization, clinical prognosis, and therapeutic targeting of human bladder tumor-initiating cells

Radioprotection in normal tissue and delayed tumor growth by blockade of CD47 signaling

CD47 is upregulated on circulating hematopoietic stem cells and leukemia cells to avoid phagocytosis

Interactions of thrombospondins with alpha4beta1 integrin and CD47 differentially modulate T cell behavior

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1673

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scholarly article

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3621085

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10.1038/SREP01673

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3

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2013-01-01T00:00:00Z

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1036227442

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23591719

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3628113

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