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Arbovirus high fidelity variant loses fitness in mosquitoes and mice

Arbovirus high fidelity variant loses fitness in mosquitoes and mice

http://www.wikidata.org/entity/Q24635860

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Chikungunya virus-vector interactions Factors shaping the adaptive landscape for arboviruses: implications for the emergence of disease Viral Polymerase-Helicase Complexes Regulate Replication Fidelity To Overcome Intracellular Nucleotide Depletion Multiple immune factors are involved in controlling acute and chronic chikungunya virus infection Arboviral bottlenecks and challenges to maintaining diversity and fitness during mosquito transmission Importance of mosquito “quasispecies” in selecting an epidemic arthropod-borne virus Genetic Drift, Purifying Selection and Vector Genotype Shape Dengue Virus Intra-host Genetic Diversity in Mosquitoes Common and unique features of viral RNA-dependent polymerases Viral quasispecies evolution Chikungunya fever: a clinical and virological investigation of outpatients on Reunion Island, South-West Indian Ocean Lamivudine/Adefovir Treatment Increases the Rate of Spontaneous Mutation of Hepatitis B Virus in Patients Mechanisms of viral mutation Genomic approaches for understanding dengue: insights from the virus, vector, and host Coronaviruses lacking exoribonuclease activity are susceptible to lethal mutagenesis: evidence for proofreading and potential therapeutics Sequence-Specific Fidelity Alterations Associated with West Nile Virus Attenuation in Mosquitoes Analysis of Dengue Virus Genetic Diversity during Human and Mosquito Infection Reveals Genetic Constraints Extremely High Mutation Rate of HIV-1 In Vivo ADP-ribosylhydrolase activity of Chikungunya virus macrodomain is critical for virus replication and virulence RNA-Seq analysis of chikungunya virus infection and identification of granzyme A as a major promoter of arthritic inflammation Gain-of-Function Research and the Relevance to Clinical Practice.Next generation sequencing of DNA-launched Chikungunya vaccine virus.Norovirus Polymerase Fidelity Contributes to Viral Transmission In Vivo.T-705 (favipiravir) induces lethal mutagenesis in influenza A H1N1 viruses in vitro Attenuation of human enterovirus 71 high-replication-fidelity variants in AG129 mice Genomic mutation rates that neutralize adaptive evolution and natural selection Closing the gap: the challenges in converging theoretical, computational, experimental and real-life studies in virus evolution Generation and characterization of influenza A viruses with altered polymerase fidelity.Mutagenesis-mediated decrease of pathogenicity as a feature of the mutant spectrum of a viral population.Coronaviruses as DNA wannabes: a new model for the regulation of RNA virus replication fidelity Vector-borne transmission imposes a severe bottleneck on an RNA virus population.Comparative mutational analyses of influenza A viruses.Structure-function relationships underlying the replication fidelity of viral RNA-dependent RNA polymerases.Ultra-deep pyrosequencing of partial surface protein genes from infectious Salmon Anaemia virus (ISAV) suggest novel mechanisms involved in transition to virulence.Mutations in coronavirus nonstructural protein 10 decrease virus replication fidelity Point mutations in the West Nile virus (Flaviviridae; Flavivirus) RNA-dependent RNA polymerase alter viral fitness in a host-dependent manner in vitro and in vivo Mutational robustness of an RNA virus influences sensitivity to lethal mutagenesis.HIV-1 and HIV-2 exhibit similar mutation frequencies and spectra in the absence of G-to-A hypermutation.Nature and Extent of Genetic Diversity of Dengue Viruses Determined by 454 Pyrosequencing.Viral population dynamics and virulence thresholds A Polymerase mechanism-based strategy for viral attenuation and vaccine development.

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P2860

Arbovirus high fidelity variant loses fitness in mosquitoes and mice

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2011 nî lūn-bûn

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2011 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

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2011 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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name

Arbovirus high fidelity variant loses fitness in mosquitoes and mice

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Arbovirus high fidelity variant loses fitness in mosquitoes and mice

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Arbovirus high fidelity variant loses fitness in mosquitoes and mice

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Arbovirus high fidelity variant loses fitness in mosquitoes and mice

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Arbovirus high fidelity variant loses fitness in mosquitoes and mice

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Arbovirus high fidelity variant loses fitness in mosquitoes and mice

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Arbovirus high fidelity variant loses fitness in mosquitoes and mice

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Arbovirus high fidelity variant loses fitness in mosquitoes and mice

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Arbovirus high fidelity variant loses fitness in mosquitoes and mice

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Arbovirus high fidelity variant loses fitness in mosquitoes and mice

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Hervé Blanc

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Lark L Coffey

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Yasnee Beeharry

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P2860

Two Chikungunya isolates from the outbreak of La Reunion (Indian Ocean) exhibit different patterns of infection in the mosquito, Aedes albopictus

A single mutation in chikungunya virus affects vector specificity and epidemic potential

A mouse model for Chikungunya: young age and inefficient type-I interferon signaling are risk factors for severe disease

Chikungunya virus in US travelers returning from India, 2006

RNA virus error catastrophe: direct molecular test by using ribavirin

Increased fidelity reduces poliovirus fitness and virulence under selective pressure in mice

Genetic and fitness changes accompanying adaptation of an arbovirus to vertebrate and invertebrate cells

Effect of alternating passage on adaptation of sindbis virus to vertebrate and invertebrate cells.

Viral RNA mutations are region specific and increased by ribavirin in a full-length hepatitis C virus replication system.

Arbovirus evolution in vivo is constrained by host alternation

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38

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108

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Antonio V Bordería

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2011-09-20T00:00:00Z

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51624072

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21896755

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Chikungunya virus

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3179076

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