Structure-based design of Taq DNA polymerases with improved properties of dideoxynucleotide incorporation - Wikidata - awgldk - TriplyDB

Structure-based design of Taq DNA polymerases with improved properties of dideoxynucleotide incorporation

Structure-based design of Taq DNA polymerases with improved properties of dideoxynucleotide incorporation

http://www.wikidata.org/entity/Q24641853

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Helix-hairpin-helix motifs confer salt resistance and processivity on chimeric DNA polymerases High-efficiency bypass of DNA damage by human DNA polymerase Q Structural basis for the synthesis of nucleobase modified DNA by Thermus aquaticus DNA polymerase Amino Acid Templating Mechanisms in Selection of Nucleotides Opposite Abasic Sites by a Family A DNA Polymerase Structures of KOD and 9°N DNA polymerases complexed with primer template duplex Structure and function of an RNA-reading thermostable DNA polymerase Crystal structures of a ddATP-, ddTTP-, ddCTP, and ddGTP- trapped ternary complex of Klentaq1: insights into nucleotide incorporation and selectivity DNA polymerases engineered by directed evolution to incorporate non-standard nucleotides Illumina error profiles: resolving fine-scale variation in metagenomic sequencing data.CyDNA: synthesis and replication of highly Cy-dye substituted DNA by an evolved polymerase.Evidence for a Watson-Crick hydrogen bonding requirement in DNA synthesis by human DNA polymerase kappa Discrimination against purine-pyrimidine mispairs in the polymerase active site of DNA polymerase I: a structural explanation.Dependence of DNA polymerase replication rate on external forces: a model based on molecular dynamics simulations Lesion bypass activity of DNA polymerase θ (POLQ) is an intrinsic property of the pol domain and depends on unique sequence inserts.Directed evolution of DNA polymerases for next-generation sequencing.Yeast DNA polymerase eta makes functional contacts with the DNA minor groove only at the incoming nucleoside triphosphate DNA polymerases provide a canon of strategies for translesion synthesis past oxidatively generated lesions.Inferring short-range linkage information from sequencing chromatograms Sequence variation within the KIV-2 copy number polymorphism of the human LPA gene in African, Asian, and European populations.Human DNA polymerase θ grasps the primer terminus to mediate DNA repair Directed evolution of polymerase function by compartmentalized self-replication Magnesium-induced assembly of a complete DNA polymerase catalytic complex.Quantitative multiplexing analysis of PCR-amplified ribosomal RNA genes by hierarchical oligonucleotide primer extension reaction.Directed polymerase evolution.DNA polymerases drive DNA sequencing-by-synthesis technologies: both past and present.Mechanistic understanding of an altered fidelity simian immunodeficiency virus reverse transcriptase mutation, V148I, identified in a pig-tailed macaque.Structural Basis for the KlenTaq DNA Polymerase Catalysed Incorporation of Alkene- versus Alkyne-Modified Nucleotides.Temperature sensitive nop2 alleles defective in synthesis of 25S rRNA and large ribosomal subunits in Saccharomyces cerevisiae.Arg660Ser mutation in Thermus aquaticus DNA polymerase I suppresses T-->C transitions: implication of wobble base pair formation at the nucleotide incorporation step.cryo-EM structures of the E. coli replicative DNA polymerase reveal its dynamic interactions with the DNA sliding clamp, exonuclease and τ.Expression and Structural Analyses of Human DNA Polymerase θ (POLQ).Self-correcting mismatches during high-fidelity DNA replication.Evolving a polymerase for hydrophobic base analogues.Dissecting chemical interactions governing RNA polymerase II transcriptional fidelity.Exploring the Chemistry of Genetic Information Storage and Propagation through Polymerase Engineering.A pre-equilibrium before nucleotide binding limits fingers subdomain closure by Klentaq1.Modeling translocation dynamics of strand displacement DNA synthesis by DNA polymerase I.An in-vitro transcription assay for development of Rotavirus VP7.Family A and B DNA Polymerases in Cancer: Opportunities for Therapeutic Interventions.Structural basis for the selective incorporation of an artificial nucleotide opposite a DNA adduct by a DNA polymerase.

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P2860

Structure-based design of Taq DNA polymerases with improved properties of dideoxynucleotide incorporation

http://www.wikidata.org/entity/Q24641853

description

1999 nî lūn-bûn

@nan

1999 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

1999 թվականի օգոստոսին հրատարակված գիտական հոդված

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1999年の論文

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1999年論文

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1999年論文

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1999年論文

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1999年論文

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1999年論文

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1999年论文

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name

Structure-based design of Taq ...... ideoxynucleotide incorporation

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Structure-based design of Taq ...... ideoxynucleotide incorporation

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Structure-based design of Taq ...... ideoxynucleotide incorporation

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type

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Structure-based design of Taq ...... ideoxynucleotide incorporation

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Structure-based design of Taq ...... ideoxynucleotide incorporation

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Structure-based design of Taq ...... ideoxynucleotide incorporation

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Structure-based design of Taq ...... ideoxynucleotide incorporation

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Structure-based design of Taq ...... ideoxynucleotide incorporation

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Structure-based design of Taq ...... ideoxynucleotide incorporation

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PNAS.96.17.9491

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Proceedings of the National Academy of Sciences of the United States of America

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Structure-based design of Taq ...... ideoxynucleotide incorporation

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P2093

G Waksman

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V Mitaxov

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Y Li

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P2860

DNA sequencing with Thermus aquaticus DNA polymerase and direct sequencing of polymerase chain reaction-amplified DNA

Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

Crystal structures of open and closed forms of binary and ternary complexes of the large fragment of Thermus aquaticus DNA polymerase I: structural basis for nucleotide incorporation.

A single residue in DNA polymerases of the Escherichia coli DNA polymerase I family is critical for distinguishing between deoxy- and dideoxyribonucleotides.

DNA sequencing with dye-labeled terminators and T7 DNA polymerase: effect of dyes and dNTPs on incorporation of dye-terminators and probability analysis of termination fragments

Slow rate of phosphodiester bond formation accounts for the strong bias that Taq DNA polymerase shows against 2',3'-dideoxynucleotide terminators.

Modified T7 DNA polymerase for DNA sequencing.

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