Synthesis and biological activity of human neuropeptide S analogues modified in position 5: identification of potent and pure neuropeptide S receptor antagonists
about
A novel brain penetrant NPS receptor antagonist, NCGC00185684, blocks alcohol-induced ERK-phosphorylation in the central amygdala and decreases operant alcohol self-administration in ratsStructure-activity relationship of imidazopyridinium analogues as antagonists of neuropeptide s receptorIn vitro and in vivo pharmacological characterization of a neuropeptide S tetrabranched derivative.Abnormal response to stress and impaired NPS-induced hyperlocomotion, anxiolytic effect and corticosterone increase in mice lacking NPSR1.Nasal application of neuropeptide S inhibits arthritis pain-related behaviors through an action in the amygdala.Multiple polymorphisms affect expression and function of the neuropeptide S receptor (NPSR1).Selective Modulation of Gq/Gs pathways by Naphtho Pyrano Pyrimidines as antagonists of the Neuropeptide S Receptor.In vitro and in vivo pharmacological characterization of nociceptin/orphanin FQ tetrabranched derivatives.Neuropeptide S facilitates mice olfactory function through activation of cognate receptor-expressing neurons in the olfactory cortex.Synthesis and separation of the enantiomers of the neuropeptide S receptor antagonist (9R/S)-3-oxo-1,1-diphenyl-tetrahydro-oxazolo[3,4-a]pyrazine-7-carboxylic acid 4-fluoro-benzylamide (SHA 68).A single-nucleotide polymorphism of human neuropeptide s gene originated from Europe shows decreased bioactivityNeuropeptide S: a novel regulator of pain-related amygdala plasticity and behaviorsFurther studies at neuropeptide s position 5: discovery of novel neuropeptide S receptor antagonistsNeuropeptide S: a transmitter system in the brain regulating fear and anxiety.Neuropeptide S receptor: recent updates on nonpeptide antagonist discovery.Central noradrenergic activity affects analgesic effect of Neuropeptide S.Anxiolytic- and panicolytic-like effects of Neuropeptide S in the mouse elevated T-maze.Neuropeptide S ameliorates olfactory spatial memory impairment induced by scopolamine and MK801 through activation of cognate receptor-expressing neurons in the subiculum complex.[d-Pen(p- t BuBzl)5]NPS, a novel ligand for the neuropeptide S receptor: structure activity and pharmacological studies
P2860
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P2860
Synthesis and biological activity of human neuropeptide S analogues modified in position 5: identification of potent and pure neuropeptide S receptor antagonists
description
2009 nî lūn-bûn
@nan
2009 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Synthesis and biological activ ...... peptide S receptor antagonists
@ast
Synthesis and biological activ ...... peptide S receptor antagonists
@en
Synthesis and biological activ ...... peptide S receptor antagonists
@nl
type
label
Synthesis and biological activ ...... peptide S receptor antagonists
@ast
Synthesis and biological activ ...... peptide S receptor antagonists
@en
Synthesis and biological activ ...... peptide S receptor antagonists
@nl
prefLabel
Synthesis and biological activ ...... peptide S receptor antagonists
@ast
Synthesis and biological activ ...... peptide S receptor antagonists
@en
Synthesis and biological activ ...... peptide S receptor antagonists
@nl
P2093
P2860
P50
P356
P1476
Synthesis and biological activ ...... peptide S receptor antagonists
@en
P2093
Anna Rizzi
Domenico Regoli
Girolamo Calò
Rainer K Reinscheid
Stella Fiorini
Valeria Camarda
P2860
P304
P356
10.1021/JM8012294
P407
P577
2009-01-01T00:00:00Z