Basal and inducible CYP1 mRNA quantitation and protein localization throughout the mouse gastrointestinal tract - Wikidata - awgldk - TriplyDB

Basal and inducible CYP1 mRNA quantitation and protein localization throughout the mouse gastrointestinal tract

Basal and inducible CYP1 mRNA quantitation and protein localization throughout the mouse gastrointestinal tract

http://www.wikidata.org/entity/Q24643992

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TLR2 controls intestinal carcinogen detoxication by CYP1A1 Cytochrome P450 1b1 in polycyclic aromatic hydrocarbon (PAH)-induced skin carcinogenesis: Tumorigenicity of individual PAHs and coal-tar extract, DNA adduction and expression of select genes in the Cyp1b1 knockout mouse An update on the role of intestinal cytochrome P450 enzymes in drug disposition Mitochondrial targeting of mouse NQO1 and CYP1B1 proteins The role of small-intestinal P450 enzymes in protection against systemic exposure of orally administered benzo[a]pyrene Organ-specific roles of CYP1A1 during detoxication of dietary benzo[a]pyrene.Oral benzo[a]pyrene-induced cancer: two distinct types in different target organs depend on the mouse Cyp1 genotype.Gene and protein expression and cellular localisation of cytochrome P450 enzymes of the 1A, 2A, 2C, 2D and 2E subfamilies in equine intestine and liver.In utero and lactational exposure to a complex mixture of polychlorinated biphenyls: toxicity in pups dependent on the Cyp1a2 and Ahr genotypes.Polycyclic aromatic hydrocarbons and digestive tract cancers: a perspective.Balancing intestinal and systemic inflammation through cell type-specific expression of the aryl hydrocarbon receptor repressor Cyp1b1 exerts opposing effects on intestinal tumorigenesis via exogenous and endogenous substrates Roles of coactivator proteins in dioxin induction of CYP1A1 and CYP1B1 in human breast cancer cells.Oral exposure to commercially available coal tar-based pavement sealcoat induces murine genetic damage and mutations.Knock-in mouse lines expressing either mitochondrial or microsomal CYP1A1: differing responses to dietary benzo[a]pyrene as proof of principle Phenotype of the Cyp1a1/1a2/1b1-/- triple-knockout mouse.CYP1A1 and CYP1A2 expression: comparing 'humanized' mouse lines and wild-type mice; comparing human and mouse hepatoma-derived cell lines Oral benzo[a]pyrene: understanding pharmacokinetics, detoxication, and consequences--Cyp1 knockout mouse lines as a paradigm.Tumor microsomal metabolism of the food toxicant, benzo(a)pyrene, in ApcMin mouse model of colon cancer.Influence of dietary fat type on benzo(a)pyrene [B(a)P] biotransformation in a B(a)P-induced mouse model of colon cancer.Butyrate alters expression of cytochrome P450 1A1 and metabolism of benzo[a]pyrene via its histone deacetylase activity in colon epithelial cell models.Empirical analysis of BMD metrics in genetic toxicology part II: in vivo potency comparisons to promote reductions in the use of experimental animals for genetic toxicity assessment.Aryl hydrocarbon receptor ligand 2,3,7,8-tetrachlorodibenzo-p-dioxin enhances liver damage in bile duct-ligated mice.Tissue-specific in vivo genetic toxicity of nine polycyclic aromatic hydrocarbons assessed using the Muta™Mouse transgenic rodent assay.Modulation of aryl hydrocarbon receptor regulated genes by acute administration of trimethylarsine oxide in the lung, kidney and heart of C57BL/6 mice.Modulation of cytochrome P450 1 (Cyp1) by vanadium in hepatic tissue and isolated hepatocyte of C57BL/6 mice.Differential modulation of aryl hydrocarbon receptor regulated enzymes by arsenite in the kidney, lung, and heart of C57BL/6 mice.Systemic immunosuppression following a single pharyngeal aspiration of 1,2:5,6-dibenzanthracene in female B6C3F1 mice.Modulation of aryl hydrocarbon receptor-regulated genes by acute administration of ammonium metavanadate in kidney, lung and heart of C57BL/6 mice.Dimethylarsinic acid modulates the aryl hydrocarbon receptor-regulated genes in C57BL/6 mice: in vivo study.Pharmacokinetics of [14C]-Benzo[a]pyrene (BaP) in humans: Impact of Co-Administration of smoked salmon and BaP dietary restriction.

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P2860

Basal and inducible CYP1 mRNA quantitation and protein localization throughout the mouse gastrointestinal tract

http://www.wikidata.org/entity/Q24643992

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2008 nî lūn-bûn

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2008 թուականի Փետրուարին հրատարակուած գիտական յօդուած

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2008 թվականի փետրվարին հրատարակված գիտական հոդված

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2008年の論文

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2008年論文

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2008年論文

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2008年论文

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name

Basal and inducible CYP1 mRNA ...... e mouse gastrointestinal tract

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Basal and inducible CYP1 mRNA ...... e mouse gastrointestinal tract

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Basal and inducible CYP1 mRNA ...... e mouse gastrointestinal tract

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Basal and inducible CYP1 mRNA ...... e mouse gastrointestinal tract

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Basal and inducible CYP1 mRNA ...... e mouse gastrointestinal tract

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Basal and inducible CYP1 mRNA ...... e mouse gastrointestinal tract

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Basal and inducible CYP1 mRNA ...... e mouse gastrointestinal tract

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J.FREERADBIOMED.2007.10.044

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Free Radical Biology and Medicine

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Basal and inducible CYP1 mRNA ...... e mouse gastrointestinal tract

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Daniel W Nebert

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Frank J Gonzalez

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Marian L Miller

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Nadine Dragin

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Shigeyuki Uno

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Timothy P Dalton

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P2860

Effects of a chargrilled meat diet on expression of CYP3A, CYP1A, and P-glycoprotein levels in healthy volunteers

Clinical importance of the cytochromes P450

Oral exposure to benzo[a]pyrene in the mouse: detoxication by inducible cytochrome P450 is more important than metabolic activation

Comparison of cytochrome P450 (CYP) genes from the mouse and human genomes, including nomenclature recommendations for genes, pseudogenes and alternative-splice variants

Oral benzo[a]pyrene in Cyp1 knockout mouse lines: CYP1A1 important in detoxication, CYP1B1 metabolism required for immune damage independent of total-body burden and clearance rate

Xenobiotic metabolism and enzyme induction in isolated rat intestinal microsomes

Cytochrome P450 CYP1B1 determines susceptibility to 7, 12-dimethylbenz[a]anthracene-induced lymphomas

Cyp1a2(-/-) null mutant mice develop normally but show deficient drug metabolism

Role of aryl hydrocarbon receptor-mediated induction of the CYP1 enzymes in environmental toxicity and cancer.

Drug metabolism by cytochromes P450 in the liver and small bowel.

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4

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