The postsynaptic density proteins Homer and Shank form a polymeric network structure
about
'Medusa-head ataxia': the expanding spectrum of Purkinje cell antibodies in autoimmune cerebellar ataxia. Part 1: Anti-mGluR1, anti-Homer-3, anti-Sj/ITPR1 and anti-CARP VIIIMutations in the SHANK2 synaptic scaffolding gene in autism spectrum disorder and mental retardationImportance of Shank3 protein in regulating metabotropic glutamate receptor 5 (mGluR5) expression and signaling at synapsesInhibition of SRGAP2 function by its human-specific paralogs induces neoteny during spine maturationAutistic-like social behaviour in Shank2-mutant mice improved by restoring NMDA receptor functionSuperresolution imaging of chemical synapses in the brain.Enhanced polyubiquitination of Shank3 and NMDA receptor in a mouse model of autismCellular and synaptic network defects in autismStructural plasticity of dendritic spinesHomer1/mGluR5 activity moderates vulnerability to chronic social stressAltered mGluR5-Homer scaffolds and corticostriatal connectivity in a Shank3 complete knockout model of autism.Pharmacological enhancement of mGlu5 receptors rescues behavioral deficits in SHANK3 knock-out mice.Phase Transition in Postsynaptic Densities Underlies Formation of Synaptic Complexes and Synaptic PlasticityA Subset of Autism-Associated Genes Regulate the Structural Stability of Neurons.Disassembly of shank and homer synaptic clusters is driven by soluble beta-amyloid(1-40) through divergent NMDAR-dependent signalling pathwaysDifferential distribution of Shank and GKAP at the postsynaptic densityWhirlin and PDZ domain-containing 7 (PDZD7) proteins are both required to form the quaternary protein complex associated with Usher syndrome type 2High-throughput sequencing of mGluR signaling pathway genes reveals enrichment of rare variants in autismMembrane palmitoylated protein 2 is a synaptic scaffold protein required for synaptic SK2-containing channel functionStriatopallidal dysfunction underlies repetitive behavior in Shank3-deficient model of autism.SHANK proteins: roles at the synapse and in autism spectrum disorder.Ultrastructural analyses in the hippocampus CA1 field in Shank3-deficient mice.Phelan-McDermid Syndrome and SHANK3: Implications for Treatment.Studying autism in rodent models: reconciling endophenotypes with comorbiditiesSynaptic profiles during neurite extension, refinement and retraction in the developing cochleaTranslational animal models of autism and neurodevelopmental disorders.Large protein assemblies formed by multivalent interactions between cadherin23 and harmonin suggest a stable anchorage structure at the tip link of stereocilia.Local palmitoylation cycles define activity-regulated postsynaptic subdomainsThe class 4 semaphorin Sema4D promotes the rapid assembly of GABAergic synapses in rodent hippocampusShank3-mutant mice lacking exon 9 show altered excitation/inhibition balance, enhanced rearing, and spatial memory deficit.Constitutive activation of CREB in mice enhances temporal association learning and increases hippocampal CA1 neuronal spine density and complexity.Homer1 alternative splicing is regulated by gonadotropin-releasing hormone and modulates gonadotropin gene expression.Hippocampus-Dependent Goal Localization by Head-Fixed Mice in Virtual Reality.Activity induced changes in the distribution of Shanks at hippocampal synapses.Dysregulation of group-I metabotropic glutamate (mGlu) receptor mediated signalling in disorders associated with Intellectual Disability and AutismIdentification and validation of novel spinophilin-associated proteins in rodent striatum using an enhanced ex vivo shotgun proteomics approach.Activation of mGluR5 attenuates NMDA-induced neurotoxicity through disruption of the NMDAR-PSD-95 complex and preservation of mitochondrial function in differentiated PC12 cells.Effect of oxidative stress on homer scaffolding proteinsEvolutionary insights into premetazoan functions of the neuronal protein homer.Electron cryotomography of postsynaptic densities during development reveals a mechanism of assembly
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P2860
The postsynaptic density proteins Homer and Shank form a polymeric network structure
description
2009 nî lūn-bûn
@nan
2009 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
The postsynaptic density proteins Homer and Shank form a polymeric network structure
@ast
The postsynaptic density proteins Homer and Shank form a polymeric network structure
@en
The postsynaptic density proteins Homer and Shank form a polymeric network structure
@nl
type
label
The postsynaptic density proteins Homer and Shank form a polymeric network structure
@ast
The postsynaptic density proteins Homer and Shank form a polymeric network structure
@en
The postsynaptic density proteins Homer and Shank form a polymeric network structure
@nl
altLabel
The Postsynaptic Density Proteins Homer and Shank Form a Polymeric Network Structure
@en
prefLabel
The postsynaptic density proteins Homer and Shank form a polymeric network structure
@ast
The postsynaptic density proteins Homer and Shank form a polymeric network structure
@en
The postsynaptic density proteins Homer and Shank form a polymeric network structure
@nl
P2093
P2860
P50
P3181
P1433
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The postsynaptic density proteins Homer and Shank form a polymeric network structure
@en
P2093
Chunyan Tang
Mariko Kato Hayashi
Marissa H Stearns
Radhakrishnan Narayanan
Rui-Ming Xu
P2860
P304
P3181
P356
10.1016/J.CELL.2009.01.050
P407
P577
2009-04-03T00:00:00Z