An african-specific functional polymorphism in KCNMB1 shows sex-specific association with asthma severity - Wikidata - awgldk - TriplyDB

An african-specific functional polymorphism in KCNMB1 shows sex-specific association with asthma severity

An african-specific functional polymorphism in KCNMB1 shows sex-specific association with asthma severity

http://www.wikidata.org/entity/Q24645999

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Peptide toxins and small-molecule blockers of BK channels Updates on the COPD gene list BK channels: multiple sensors, one activation gate In-Depth Study of the Interaction, Sensitivity, and Gating Modulation by PUFAs on K+ Channels; Interaction and New Targets Genome-wide interaction studies reveal sex-specific asthma risk alleles.Treatment of experimental asthma using a single small molecule with anti-inflammatory and BK channel-activating properties.A BK (Slo1) channel journey from molecule to physiology.Location of modulatory beta subunits in BK potassium channels.Structural determinants of phosphatidylinositol 4,5-bisphosphate (PIP2) regulation of BK channel activity through the RCK1 Ca2+ coordination site.The regulation of BK channel activity by pre- and post-translational modifications.African ancestry is associated with asthma risk in African Americans.Gene-environment interactions in human disease: nuisance or opportunity?Single-channel kinetics of BK (Slo1) channels.Molecular mechanism underlying β1 regulation in voltage- and calcium-activated potassium (BK) channels.Genomic architecture of asthma differs by sex.Large conductance, calcium- and voltage-gated potassium (BK) channels: regulation by cholesterol.The Association of African Ancestry and elevated creatinine in the Coronary Artery Risk Development in Young Adults (CARDIA) Study.Positions of β2 and β3 subunits in the large-conductance calcium- and voltage-activated BK potassium channel IFNG genotype and sex interact to influence the risk of childhood asthma Mechanism of the modulation of BK potassium channel complexes with different auxiliary subunit compositions by the omega-3 fatty acid DHA.Novel cell-free high-throughput screening method for pharmacological tools targeting K+ channels.Transduction of voltage and Ca2+ signals by Slo1 BK channels.Functional effects of KCNQ K(+) channels in airway smooth muscle Molecular mechanisms of BK channel activation.Hypertension of Kcnmb1-/- is linked to deficient K secretion and aldosteronism Role of BKbeta1 in Na+ reabsorption by cortical collecting ducts of Na+-deprived mice Ion channels in asthma.The BK channel: a vital link between cellular calcium and electrical signaling.A randomized clinical trial of a culturally responsive intervention for African American women with asthma.International Union of Basic and Clinical Pharmacology. C. Nomenclature and Properties of Calcium-Activated and Sodium-Activated Potassium Channels.Comparative effects of H+ and Ca2+ on large-conductance Ca2+- and voltage-gated Slo1 K+ channels.An extracellular domain of the accessory β1 subunit is required for modulating BK channel voltage sensor and gate.Allosteric-activation mechanism of BK channel gating ring triggered by calcium ions.The large-conductance calcium-activated potassium channel holds the key to the conundrum of familial hypokalemic periodic paralysis.Molecular structure and function of big calcium-activated potassium channels in skeletal muscle: pharmacological perspectives.Health Disparities in Patients with Pulmonary Arterial Hypertension: A Blueprint for Action. An Official American Thoracic Society Statement.BK channel activation by tungstate requires the β1 subunit extracellular loop residues essential to modulate voltage sensor function and channel gating.

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P2860

An african-specific functional polymorphism in KCNMB1 shows sex-specific association with asthma severity

http://www.wikidata.org/entity/Q24645999

description

2008 nî lūn-bûn

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2008 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

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2008 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年论文

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An african-specific functional ...... sociation with asthma severity

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An african-specific functional ...... sociation with asthma severity

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An african-specific functional ...... sociation with asthma severity

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An african-specific functional ...... sociation with asthma severity

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An african-specific functional ...... sociation with asthma severity

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An african-specific functional ...... sociation with asthma severity

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An african-specific functional ...... sociation with asthma severity

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An african-specific functional ...... sociation with asthma severity

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An african-specific functional ...... sociation with asthma severity

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Human Molecular Genetics

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An african-specific functional ...... sociation with asthma severity

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Bin Wang

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Celeste Eng

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Esteban González Burchard

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Gunjan Kumar

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H Geoffrey Watson

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Kelley Meade

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Kenneth B Beckman

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Kevin B Weiss

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L Keoki Williams

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Max A Seibold

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Spirometric reference values from a sample of the general U.S. population

Inference of population structure using multilocus genotype data

Gain-of-function mutation in the KCNMB1 potassium channel subunit is associated with low prevalence of diastolic hypertension

Determinant for beta-subunit regulation in high-conductance voltage-activated and Ca(2+)-sensitive K+ channels: an additional transmembrane region at the N terminus

Signaling and regulation of G protein-coupled receptors in airway smooth muscle

The BK channel beta1 subunit gene is associated with human baroreflex and blood pressure regulation

Standardization of Spirometry, 1994 Update. American Thoracic Society

Trends in hypertension prevalence, awareness, treatment, and control in older U.S. adults: data from the National Health and Nutrition Examination Survey 1988 to 2004.

Characterization of the severe asthma phenotype by the National Heart, Lung, and Blood Institute's Severe Asthma Research Program.

Association between a sequence variant in the IL-4 gene promoter and FEV(1) in asthma.

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2681-90

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10.1093/HMG/DDN168

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17

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17

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18535015

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2733805

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