Evolutionary and functional insights into the mechanism underlying high-altitude adaptation of deer mouse hemoglobin
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Structure of the altitude adapted hemoglobin of guinea pig in the R2-stateDeer mouse hemoglobin exhibits a lowered oxygen affinity owing to mobility of the E helixSequencing of 50 human exomes reveals adaptation to high altitudeGenetic architecture of a feeding adaptation: garter snake (Thamnophis) resistance to tetrodotoxin bearing preyGenetic differences in hemoglobin function between highland and lowland deer miceRegulatory changes contribute to the adaptive enhancement of thermogenic capacity in high-altitude deer micePhenotypic plasticity and genetic adaptation to high-altitude hypoxia in vertebratesWidespread phenotypic and genetic divergence along altitudinal gradients in animalsExperimental approaches to evaluate the contributions of candidate protein-coding mutations to phenotypic evolutionGene duplication as a mechanism of genomic adaptation to a changing environmentReverse engineering the cooperative machinery of human hemoglobinGenetic convergence in the adaptation of dogs and humans to the high-altitude environment of the tibetan plateauAncestral genes can control the ability of horizontally acquired loci to confer new traitsConvergent Evolution of Hemoglobin Function in High-Altitude Andean Waterfowl Involves Limited Parallelism at the Molecular Sequence LevelGenome-wide analysis reveals adaptation to high altitudes in Tibetan sheepEpistasis constrains mutational pathways of hemoglobin adaptation in high-altitude pikasFin whale MDH-1 and MPI allozyme variation is not reflected in the corresponding DNA sequencesRepeated evolution of chimeric fusion genes in the β-globin gene family of laurasiatherian mammalsA comparative study of rhodopsin function in the great bowerbird (Ptilonorhynchus nuchalis): Spectral tuning and light-activated kinetics.Novel genomic resources for a climate change sensitive mammal: characterization of the American pika transcriptome.Differential high-altitude adaptation and restricted gene flow across a mid-elevation hybrid zone in Andean tit-tyrant flycatchers.Stability-Mediated Epistasis Restricts Accessible Mutational Pathways in the Functional Evolution of Avian Hemoglobin.A coastal cline in sodium accumulation in Arabidopsis thaliana is driven by natural variation of the sodium transporter AtHKT1;1.Functional Genomic Insights into Regulatory Mechanisms of High-Altitude AdaptationEvolutionary and functional properties of a two-locus beta-globin polymorphism in Indian house mice.Gene expression of the liver in response to chronic hypoxiaExpression and purification of recombinant hemoglobin in Escherichia coli.Whole-genome sequencing of six dog breeds from continuous altitudes reveals adaptation to high-altitude hypoxia.Gene duplication, genome duplication, and the functional diversification of vertebrate globins.Repeated elevational transitions in hemoglobin function during the evolution of Andean hummingbirds.A structural perspective of compensatory evolutionMultilocus coalescent analysis of haemoglobin differentiation between low- and high-altitude populations of crested ducks (Lophonetta specularioides).Molecular evolution of cytochrome C oxidase underlies high-altitude adaptation in the bar-headed goose.Population genomics and local adaptation in wild isolates of a model microbial eukaryoteIntegrating evolutionary and functional approaches to infer adaptation at specific lociEvolutionary biochemistry: revealing the historical and physical causes of protein properties.Integrating evolutionary and functional tests of adaptive hypotheses: a case study of altitudinal differentiation in hemoglobin function in an Andean Sparrow, Zonotrichia capensisChronic hypoxia increases insulin-stimulated glucose uptake in mouse soleus muscleIncreased blood-oxygen binding affinity in Tibetan and Han Chinese residents at 4200 mTranscriptome resources for the white-footed mouse (Peromyscus leucopus): new genomic tools for investigating ecologically divergent urban and rural populations.
P2860
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P2860
Evolutionary and functional insights into the mechanism underlying high-altitude adaptation of deer mouse hemoglobin
description
2009 nî lūn-bûn
@nan
2009 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Evolutionary and functional in ...... ation of deer mouse hemoglobin
@ast
Evolutionary and functional in ...... ation of deer mouse hemoglobin
@en
Evolutionary and functional in ...... ation of deer mouse hemoglobin
@nl
type
label
Evolutionary and functional in ...... ation of deer mouse hemoglobin
@ast
Evolutionary and functional in ...... ation of deer mouse hemoglobin
@en
Evolutionary and functional in ...... ation of deer mouse hemoglobin
@nl
prefLabel
Evolutionary and functional in ...... ation of deer mouse hemoglobin
@ast
Evolutionary and functional in ...... ation of deer mouse hemoglobin
@en
Evolutionary and functional in ...... ation of deer mouse hemoglobin
@nl
P2093
P2860
P50
P356
P1476
Evolutionary and functional in ...... ation of deer mouse hemoglobin
@en
P2093
Amy M Runck
Hideaki Moriyama
Jay F Storz
John K Kelly
Roy E Weber
P2860
P304
P356
10.1073/PNAS.0905224106
P407
P577
2009-08-25T00:00:00Z