Cutting edge: selective tyrosine dephosphorylation of interferon-activated nuclear STAT5 by the VHR phosphatase
about
Protein tyrosine phosphatases as wardens of STAT signalingDimeric Quaternary Structure of the Prototypical Dual Specificity Phosphatase VH1JNK pathway-associated phosphatase dephosphorylates focal adhesion kinase and suppresses cell migration.PTP1B suppresses prolactin activation of Stat5 in breast cancer cells.Specificity profiling of dual specificity phosphatase vaccinia VH1-related (VHR) reveals two distinct substrate binding modesDual-specificity phosphatase 23 mediates GCM1 dephosphorylation and activationVaccinia H1-related phosphatase is a phosphatase of ErbB receptors and is down-regulated in non-small cell lung cancerTranscriptional regulation via TF-modifying enzymes: an integrative model-based analysis.Division of labor by dual feedback regulators controls JAK2/STAT5 signaling over broad ligand range.Laforin, a dual-specificity phosphatase involved in Lafora disease, is phosphorylated at Ser25 by AMP-activated protein kinase.Dual-Specificity Phosphatase 4 Regulates STAT5 Protein Stability and Helper T Cell Polarization.Identification of Cell Type-Specific Differences in Erythropoietin Receptor Signaling in Primary Erythroid and Lung Cancer Cells.DUSP4 deficiency enhances CD25 expression and CD4+ T-cell proliferation without impeding T-cell development.Dynamic trafficking of STAT5 depends on an unconventional nuclear localization signalRegulation of TCR signalling by tyrosine phosphatases: from immune homeostasis to autoimmunity.VHR/DUSP3 phosphatase: structure, function and regulation.Deficiency in VHR/DUSP3, a suppressor of focal adhesion kinase, reveals its role in regulating cell adhesion and migration.Intramolecular hydrophobic interactions are critical mediators of STAT5 dimerization.Dual-Specificity Phosphatase 3 Deletion Protects Female, but Not Male, Mice from Endotoxemia-Induced and Polymicrobial-Induced Septic Shock.Dusp3 deletion in mice promotes experimental lung tumour metastasis in a macrophage dependent manner.A genetically encoded sulfotyrosine for VHR function research.Combined experimental and bioinformatics analysis for the prediction and identification of VHR/DUSP3 nuclear targets related to DNA damage and repair.DUSP23 is over-expressed and linked to the expression of DNMTs in CD4+ T cells from systemic lupus erythematosus patients.Reduced levels of Dusp3/Vhr phosphatase impair normal spindle bipolarity in an Erk1/2 activity-dependent manner.Revisiting the roles of VHR/DUSP3 phosphatase in human diseases
P2860
Q26861574-AE20A65B-CFCA-4D7A-AD60-446FDFBE1F0BQ27653744-A97C9D2C-17AD-4219-BF09-C1B8F116D1A9Q33648402-26B21437-AED0-42EE-81F1-34BF29AFE178Q34358316-83F98E96-1CA2-4F1D-BF10-1F294471290DQ34549319-4BD79C45-066B-47F7-A808-A1392D7110E3Q34559644-3964D734-7C3E-4498-9361-8D26B2F6FEDBQ34695575-CB2196C8-F89B-41B6-BDFF-52A5EC3EBE5FQ35088085-E7FD5176-14CC-4AF9-B30A-55CC561E25C2Q35176382-C6932D8F-1CD1-4C0B-8573-B145FA82CD0EQ35821706-F20B1A2B-5CF8-4D9A-BD48-6BF4C1042B1CQ35879703-F542A329-3E13-4081-95DC-9FAADC95EF3EQ36095789-BB97AFF1-9F86-4F8C-B7A3-485913009839Q36453016-B90FCBAB-0D49-4740-97ED-534079F83D2CQ37061528-C0DEC9B5-493A-4A75-8A6A-1175A56655F9Q38031978-0F2B1BA0-D002-4E91-9E98-103D5CBEE683Q38372232-696C59BD-D669-45C0-BED0-98278D09AB34Q38651960-5252B082-D3C6-4E9F-B4C5-4A828C82D3EAQ38810236-648E59F0-BA20-40D7-A916-76E21A1B8BC9Q40077080-428C5E7A-DB5B-47D9-A112-D94928FE14E8Q41987298-D068E76A-B6C3-45DF-8A40-814C99057B00Q42771758-5D343BC6-06F9-46F2-B382-EB7E00BE1149Q46610361-512C203E-C740-4E32-AB3A-6F9BFF2AFB19Q51397327-1C67F73B-4668-4DAC-B195-44AB13D4C29CQ51637887-8B96C2C4-D2E5-4A89-A30F-B7D91E742481Q58699207-97765051-92E3-4162-9DC1-DEA1DC2FE82A
P2860
Cutting edge: selective tyrosine dephosphorylation of interferon-activated nuclear STAT5 by the VHR phosphatase
description
2007 nî lūn-bûn
@nan
2007 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Cutting edge: selective tyrosi ...... r STAT5 by the VHR phosphatase
@ast
Cutting edge: selective tyrosi ...... r STAT5 by the VHR phosphatase
@en
Cutting edge: selective tyrosi ...... r STAT5 by the VHR phosphatase
@nl
type
label
Cutting edge: selective tyrosi ...... r STAT5 by the VHR phosphatase
@ast
Cutting edge: selective tyrosi ...... r STAT5 by the VHR phosphatase
@en
Cutting edge: selective tyrosi ...... r STAT5 by the VHR phosphatase
@nl
prefLabel
Cutting edge: selective tyrosi ...... r STAT5 by the VHR phosphatase
@ast
Cutting edge: selective tyrosi ...... r STAT5 by the VHR phosphatase
@en
Cutting edge: selective tyrosi ...... r STAT5 by the VHR phosphatase
@nl
P2093
P2860
P3181
P1476
Cutting edge: selective tyrosi ...... r STAT5 by the VHR phosphatase
@en
P2093
Andres Alonso
Fabio Cerignoli
Michael David
Richard Hoyt
Tomas Mustelin
P2860
P304
P3181
P356
10.4049/JIMMUNOL.179.6.3402
P407
P577
2007-09-15T00:00:00Z