Transcription of the sodium/myo-inositol cotransporter gene is regulated by multiple tonicity-responsive enhancers spread over 50 kilobase pairs in the 5'-flanking region
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Tonicity-responsive enhancer binding protein, a rel-like protein that stimulates transcription in response to hypertonicityThe role of hyperosmotic stress in inflammation and diseaseTransgenic mice expressing dominant-negative osmotic-response element-binding protein (OREBP) in lens exhibit fiber cell elongation defect associated with increased DNA breaksIntracellular water homeostasis and the mammalian cellular osmotic stress responseStructure and characterization of the mouse UT-A gene (Slc14a2).Inducible nucleosome depletion at OREBP-binding-sites by hypertonic stress.Targeted disruption of hsp70.1 sensitizes to osmotic stress.Determination of the NFAT5/TonEBP transcription factor in the human and ovine placentaSurvival in hostile environments: strategies of renal medullary cells.Inositol and higher inositol phosphates in neural tissues: homeostasis, metabolism and functional significance.Dehydration activates an NF-kappaB-driven, COX2-dependent survival mechanism in renal medullary interstitial cells.Nuclear import of a lipid-modified transcription factor: mobilization of NFAT5 isoform a by osmotic stressDownregulation of the taurine transporter TauT during hypo-osmotic stress in NIH3T3 mouse fibroblastsEvolutionary relationships among Rel domains indicate functional diversification by recombination.MAP kinases and the adaptive response to hypertonicity: functional preservation from yeast to mammals.Elevated extracellular glucose and uncontrolled type 1 diabetes enhance NFAT5 signaling and disrupt the transverse tubular network in mouse skeletal muscleTyrosine kinase inhibitors and immunosuppressants perturb the myo-inositol but not the betaine cotransporter in isotonic and hypertonic MDCK cells.LPS-induced NFκB enhanceosome requires TonEBP/NFAT5 without DNA binding.NFAT5 in cellular adaptation to hypertonic stress - regulations and functional significanceTonEBP suppresses IL-10-mediated immunomodulation.SNAT2 amino acid transporter is regulated by amino acids of the SLC6 gamma-aminobutyric acid transporter subfamily in neocortical neurons and may play no role in delivering glutamine for glutamatergic transmission.Ambient tonicity and intestinal cytochrome CYP3A.Osmolality/salinity-responsive enhancers (OSREs) control induction of osmoprotective genes in euryhaline fish.Is prenatal myo-inositol deficiency a mechanism of CNS injury in galactosemia?Inositol transport proteins.Transcriptional responses to thermal acclimation in the eurythermal fish Gillichthys mirabilis (Cooper 1864).Activation of osmolyte pathways in inflammatory myopathy and Duchenne muscular dystrophy points to osmoregulation as a contributing pathogenic mechanism.Phosphorylation by casein kinase 1 regulates tonicity-induced osmotic response element-binding protein/tonicity enhancer-binding protein nucleocytoplasmic trafficking.TonEBP/NFAT5 stimulates transcription of HSP70 in response to hypertonicity.The expression of aquaporin-1 in the medulla of the kidney is dependent on the transcription factor associated with hypertonicity, TonEBP.Up-regulation of human myo-inositol oxygenase by hyperosmotic stress in renal proximal tubular epithelial cells.Hypertonicity-induced aquaporin-1 (AQP1) expression is mediated by the activation of MAPK pathways and hypertonicity-responsive element in the AQP1 gene.Involvement of multiple kinase pathways in stimulation of gene transcription by hypertonicity.Hypertonicity-induced expression of aquaporin 3 in MDCK cells.Nuclear redistribution of tonicity-responsive enhancer binding protein requires proteasome activity.Characterization of cis-elements required for osmotic response of rat Na(+)/H(+) exchanger-2 (NHE-2) gene.Tonicity-dependent induction of Sgk1 expression has a potential role in dehydration-induced natriuresis in rodents.Hypotonicity reduces the activity of murine aquaporin-2 promoter induced by dibutyryl cAMP.Does the intracellular ionic concentration or the cell water content (cell volume) determine the activity of TonEBP in NIH3T3 cells?Amino acid depletion activates TonEBP and sodium-coupled inositol transport.
P2860
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P2860
Transcription of the sodium/myo-inositol cotransporter gene is regulated by multiple tonicity-responsive enhancers spread over 50 kilobase pairs in the 5'-flanking region
description
1998 nî lūn-bûn
@nan
1998 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Transcription of the sodium/my ...... airs in the 5'-flanking region
@ast
Transcription of the sodium/my ...... airs in the 5'-flanking region
@en
Transcription of the sodium/my ...... airs in the 5'-flanking region
@nl
type
label
Transcription of the sodium/my ...... airs in the 5'-flanking region
@ast
Transcription of the sodium/my ...... airs in the 5'-flanking region
@en
Transcription of the sodium/my ...... airs in the 5'-flanking region
@nl
prefLabel
Transcription of the sodium/my ...... airs in the 5'-flanking region
@ast
Transcription of the sodium/my ...... airs in the 5'-flanking region
@en
Transcription of the sodium/my ...... airs in the 5'-flanking region
@nl
P2093
P2860
P3181
P356
P1476
Transcription of the sodium/my ...... airs in the 5'-flanking region
@en
P2093
P2860
P304
P3181
P356
10.1074/JBC.273.32.20615
P407
P50
P577
1998-08-07T00:00:00Z