Direct association with and dephosphorylation of Jak2 kinase by the SH2-domain-containing protein tyrosine phosphatase SHP-1
about
Leishmania-induced IRAK-1 inactivation is mediated by SHP-1 interacting with an evolutionarily conserved KTIM motifRegulation of acidification and apoptosis by SHP-1 and Bcl-2hTid-1, a human DnaJ protein, modulates the interferon signaling pathwayJanus kinases in immune cell signalingSHP-1 binds and negatively modulates the c-Kit receptor by interaction with tyrosine 569 in the c-Kit juxtamembrane domain.The JAK-binding protein JAB inhibits Janus tyrosine kinase activity through binding in the activation loopThe distal region and receptor tyrosines of the Epo receptor are non-essential for in vivo erythropoiesisets-2 is a target for an akt (Protein kinase B)/jun N-terminal kinase signaling pathway in macrophages of motheaten-viable mutant miceMolecular mechanism of interleukin-2-induced mucosal homeostasisT cell recognition of weak ligands: roles of signaling, receptor number, and affinityIdentification of SH2-Bbeta as a substrate of the tyrosine kinase JAK2 involved in growth hormone signalingOntological visualization of protein-protein interactionsProtein tyrosine phosphatases as wardens of STAT signalingThe human homologue of the yeast proteins Skb1 and Hsl7p interacts with Jak kinases and contains protein methyltransferase activity.Differential regulation of leukemia inhibitory factor-stimulated neuronal gene expression by protein phosphatases SHP-1 and SHP-2 through mitogen-activated protein kinase-dependent and -independent pathwaysSpecific dephosphorylation of the Lck tyrosine protein kinase at Tyr-394 by the SHP-1 protein-tyrosine phosphataseJAK2 tyrosine kinase phosphorylates PAK1 and regulates PAK1 activity and functionsSrc kinase activity is regulated by the SHP-1 protein-tyrosine phosphataseLipoarabinomannan of Mycobacterium tuberculosis promotes protein tyrosine dephosphorylation and inhibition of mitogen-activated protein kinase in human mononuclear phagocytes. Role of the Src homology 2 containing tyrosine phosphatase 1Phosphotyrosine 1173 mediates binding of the protein-tyrosine phosphatase SHP-1 to the epidermal growth factor receptor and attenuation of receptor signalingSLP-76 is a direct substrate of SHP-1 recruited to killer cell inhibitory receptorsProteasomes regulate erythropoietin receptor and signal transducer and activator of transcription 5 (STAT5) activation. Possible involvement of the ubiquitinated Cis proteinSTAT3 as a therapeutic target in head and neck cancerRegulation of expression of the rat SOCS-3 gene in hepatocytes by growth hormone, interleukin-6 and glucocorticoids mRNA analysis and promoter characterizationSHP1 and SHP2 protein-tyrosine phosphatases associate with betac after interleukin-3-induced receptor tyrosine phosphorylation. Identification of potential binding sites and substratesProtein tyrosine phosphatases in the JAK/STAT pathwaySrc homology domain 2-containing protein-tyrosine phosphatase-1 (SHP-1) binds and dephosphorylates G(alpha)-interacting, vesicle-associated protein (GIV)/Girdin and attenuates the GIV-phosphatidylinositol 3-kinase (PI3K)-Akt signaling pathway.The signal transduction of the growth hormone receptor is regulated by the ubiquitin/proteasome system and continues after endocytosis.Tumor suppression by phospholipase C-beta3 via SHP-1-mediated dephosphorylation of Stat5.Negative regulation of the JAK/STAT pathway.The benzoxathiolone LYR-71 down-regulates interferon-gamma-inducible pro-inflammatory genes by uncoupling tyrosine phosphorylation of STAT-1 in macrophagesAbnormalities of cytokine receptor signalling contributing to diseases of red blood cell production.Alteration of SHP-1/p-STAT3 Signaling: A Potential Target for Anticancer Therapy.A robust error model for iTRAQ quantification reveals divergent signaling between oncogenic FLT3 mutants in acute myeloid leukemia.Inhibitory roles for SHP-1 and SOCS-3 following pituitary proopiomelanocortin induction by leukemia inhibitory factorSHP-1 deficiency and increased inflammatory gene expression in PBMCs of multiple sclerosis patients.The molecular regulation of Janus kinase (JAK) activationSuppression of STAT5 functions in liver, mammary glands, and T cells in cytokine-inducible SH2-containing protein 1 transgenic miceJanus kinases: components of multiple signaling pathways.Hematopoietic factor erythropoietin fosters neuroprotection through novel signal transduction cascades.
P2860
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P2860
Direct association with and dephosphorylation of Jak2 kinase by the SH2-domain-containing protein tyrosine phosphatase SHP-1
description
1996 nî lūn-bûn
@nan
1996 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
name
Direct association with and de ...... ein tyrosine phosphatase SHP-1
@ast
Direct association with and de ...... ein tyrosine phosphatase SHP-1
@en
Direct association with and de ...... ein tyrosine phosphatase SHP-1
@nl
type
label
Direct association with and de ...... ein tyrosine phosphatase SHP-1
@ast
Direct association with and de ...... ein tyrosine phosphatase SHP-1
@en
Direct association with and de ...... ein tyrosine phosphatase SHP-1
@nl
prefLabel
Direct association with and de ...... ein tyrosine phosphatase SHP-1
@ast
Direct association with and de ...... ein tyrosine phosphatase SHP-1
@en
Direct association with and de ...... ein tyrosine phosphatase SHP-1
@nl
P2093
P2860
P356
P1476
Direct association with and de ...... ein tyrosine phosphatase SHP-1
@en
P2093
P2860
P304
P356
10.1128/MCB.16.12.6985
P407
P577
1996-12-01T00:00:00Z