A novel IL-1 family cytokine, IL-33, potently activates human eosinophils - Wikidata - awgldk - TriplyDB

A novel IL-1 family cytokine, IL-33, potently activates human eosinophils

A novel IL-1 family cytokine, IL-33, potently activates human eosinophils

http://www.wikidata.org/entity/Q24647672

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IL-33 enhances Siglec-8 mediated apoptosis of human eosinophils The IL-1-like cytokine IL-33 is inactivated after maturation by caspase-1 Re-defining the unique roles for eosinophils in allergic respiratory inflammation Innate lymphocyte cells in asthma phenotypes Hematopoietic progenitor cells are innate Th2 cytokine-producing cells Sequence variants affecting eosinophil numbers associate with asthma and myocardial infarction Paracrine IL-33 stimulation enhances lipopolysaccharide-mediated macrophage activation Application of the adverse outcome pathway (AOP) concept to structure the available in vivo and in vitro mechanistic data for allergic sensitization to food proteins Transcriptional regulation of murine IL-33 by TLR and non-TLR agonists.Interleukin-33 in asthma: how big of a role does it play?Transcriptional signatures of Itk-deficient CD3+, CD4+ and CD8+ T-cells The ST2/IL-33 Axis in Immune Cells during Inflammatory Diseases.Understanding Interleukin 33 and Its Roles in Eosinophil Development Gene transcription changes in asthmatic chronic rhinosinusitis with nasal polyps and comparison to those in atopic dermatitis.IL-33 is produced by mast cells and regulates IgE-dependent inflammation.Evaluation of candidate genes in a genome-wide association study of childhood asthma in Mexicans Cytokines (interleukin-9, IL-17, IL-22, IL-25 and IL-33) and asthma.Role of IL-33 and its receptor in T cell-mediated autoimmune diseases Human eosinophils recognize endogenous danger signal crystalline uric acid and produce proinflammatory cytokines mediated by autocrine ATP.25-Hydroxyvitamin D, IL-31, and IL-33 in children with allergic disease of the airways Synovial fibroblasts promote the expression and granule accumulation of tryptase via interleukin-33 and its receptor ST-2 (IL1RL1)Interleukin 33: a switch-hitting cytokine.Distinct eosinophil cytokine expression patterns in skin diseases - the possible existence of functionally different eosinophil subpopulations.Construction of human nonimmune library and selection of scFvs against IL-33.Identification of genes expressed by human airway eosinophils after an in vivo allergen challenge.Adiposity, fractional exhaled nitric oxide, and asthma in U.S. children.Eosinophils: multifaceted biological properties and roles in health and disease A novel interleukin 33/ST2 signaling regulates inflammatory response in human corneal epithelium.The danger signal, extracellular ATP, is a sensor for an airborne allergen and triggers IL-33 release and innate Th2-type responses IL-33 and Airway Inflammation.The IL-33/ST2 pathway: therapeutic target and novel biomarker.Phenotypic and genotypic association of epithelial IL1RL1 to human TH2-like asthma Identification of constitutively active interleukin 33 (IL-33) splice variant.The immune-modulating cytokine and endogenous Alarmin interleukin-33 is upregulated in skin exposed to inflammatory UVB radiation.Global secretome characterization of A549 human alveolar epithelial carcinoma cells during Mycoplasma pneumoniae infection.Dusp5 negatively regulates IL-33-mediated eosinophil survival and function Eosinophils: changing perspectives in health and disease.IL-33 expands suppressive CD11b+ Gr-1(int) and regulatory T cells, including ST2L+ Foxp3+ cells, and mediates regulatory T cell-dependent promotion of cardiac allograft survival.Toll/interleukin-1 receptor member ST2 exhibits higher soluble levels in type 2 diabetes, especially when accompanied with left ventricular diastolic dysfunction.Innate lymphoid cells responding to IL-33 mediate airway hyperreactivity independently of adaptive immunity.

P2860

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P2860

A novel IL-1 family cytokine, IL-33, potently activates human eosinophils

http://www.wikidata.org/entity/Q24647672

description

2008 nî lūn-bûn

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2008 թուականի Յունիսին հրատարակուած գիտական յօդուած

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2008 թվականի հունիսին հրատարակված գիտական հոդված

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年论文

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name

A novel IL-1 family cytokine, IL-33, potently activates human eosinophils

@ast

A novel IL-1 family cytokine, IL-33, potently activates human eosinophils

@en

A novel IL-1 family cytokine, IL-33, potently activates human eosinophils

@nl

type

label

A novel IL-1 family cytokine, IL-33, potently activates human eosinophils

@ast

A novel IL-1 family cytokine, IL-33, potently activates human eosinophils

@en

A novel IL-1 family cytokine, IL-33, potently activates human eosinophils

@nl

prefLabel

A novel IL-1 family cytokine, IL-33, potently activates human eosinophils

@ast

A novel IL-1 family cytokine, IL-33, potently activates human eosinophils

@en

A novel IL-1 family cytokine, IL-33, potently activates human eosinophils

@nl

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J.JACI.2008.04.005

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The Journal of Allergy and Clinical Immunology

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A novel IL-1 family cytokine, IL-33, potently activates human eosinophils

@en

P2093

Hirohito Kita

http://www.w3.org/2001/XMLSchema#string

Juhan Yoon

http://www.w3.org/2001/XMLSchema#string

Kathleen R Bartemes

http://www.w3.org/2001/XMLSchema#string

Koji Iijima

http://www.w3.org/2001/XMLSchema#string

W Brett Cherry

http://www.w3.org/2001/XMLSchema#string

P2860

IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines

T1/ST2 is preferentially expressed on murine Th2 cells, independent of interleukin 4, interleukin 5, and interleukin 10, and important for Th2 effector function

A new nomenclature for IL-1-family genes

Decreased expression of membrane IL-5 receptor alpha on human eosinophils: I. Loss of membrane IL-5 receptor alpha on airway eosinophils and increased soluble IL-5 receptor alpha in the airway after allergen challenge

Soluble ST2 blocks interleukin-33 signaling in allergic airway inflammation

Eosinophil cytokines.

Identification of mast cell progenitors in adult mice

The IL-1 receptor-related T1 antigen is expressed on immature and mature mast cells and on fetal blood mast cell progenitors.

Recombinant human interleukin 5 is a selective activator of human eosinophil function

Selective expression of a stable cell surface molecule on type 2 but not type 1 helper T cells.

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10.1016/J.JACI.2008.04.005

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6

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121

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5316675

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18539196

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