Identification of a 170-kDa protein over-expressed in lung cancers
about
The let-7 microRNA interfaces extensively with the translation machinery to regulate cell differentiationeIF3 targets cell-proliferation messenger RNAs for translational activation or repressionSchwannomin inhibits tumorigenesis through direct interaction with the eukaryotic initiation factor subunit c (eIF3c)The cholangiocyte marker, BD. 1, forms a stable complex with CLIP170 and shares an identity with eIF3a, a multifunctional subunit of the eIF3 initiation complexThe translation initiation factor eIF3i up-regulates vascular endothelial growth factor A, accelerates cell proliferation, and promotes angiogenesis in embryonic development and tumorigenesis.Translation initiation factor eIF4G-1 binds to eIF3 through the eIF3e subunit.Loss of the eukaryotic initiation factor 3f in pancreatic cancer.Association of positively selected eIF3a polymorphisms with toxicity of platinum-based chemotherapy in NSCLC patientsRole of eIF3a in regulating cisplatin sensitivity and in translational control of nucleotide excision repair of nasopharyngeal carcinoma.Translational regulation of RPA2 via internal ribosomal entry site and by eIF3aN-myc downstream regulated 1 (NDRG1) is regulated by eukaryotic initiation factor 3a (eIF3a) during cellular stress caused by iron depletion.Translation initiation and its deregulation during tumorigenesisGenomic profiles in stage I primary non small cell lung cancer using comparative genomic hybridization analysis of cDNA microarrays.The prognostic value of altered eIF3a and its association with p27 in non-small cell lung cancers.Postgenomic global analysis of translational control induced by oncogenic signaling.Computational discovery of pathway-level genetic vulnerabilities in non-small-cell lung cancer.Overexpression of eIF3a in Squamous Cell Carcinoma of the Oral Cavity and Its Putative Relation to Chemotherapy Response.EIF3 p170, a mediator of mimosine effect on protein synthesis and cell cycle progression.MiR-488 inhibits proliferation and cisplatin sensibility in non-small-cell lung cancer (NSCLC) cells by activating the eIF3a-mediated NER signaling pathway.eIF3 controls cell size independently of S6K1-activity.A systematic analysis of miRNA transcriptome in Marek's disease virus-induced lymphoma reveals novel and differentially expressed miRNAs.Loss of the eukaryotic initiation factor 3f in melanoma.Spectrin domain of eukaryotic initiation factor 3a is the docking site for formation of the a:b:i:g subcomplex.Silencing of translation initiation factor eIF3b promotes apoptosis in osteosarcoma cellsTranslational control gone awry: a new mechanism of tumorigenesis and novel targets of cancer treatments.Inhibitors of translation initiation as cancer therapeutics.The oncogenic role of EIF3D is associated with increased cell cycle progression and motility in prostate cancer.Knockdown of eIF3d inhibits cell proliferation through G2/M phase arrest in non-small cell lung cancer.Synthesis, pharmacophores, and mechanism study of pyridin-2(1H)-one derivatives as regulators of translation initiation factor 3A.Eukaryotic translation initiation factors and cancer.Uptake of 2-NBDG as a method to monitor therapy response in breast cancer cell lines.Individual overexpression of five subunits of human translation initiation factor eIF3 promotes malignant transformation of immortal fibroblast cells.Role of eIF3 p170 in controlling synthesis of ribonucleotide reductase M2 and cell growth.EIF3D promotes gallbladder cancer development by stabilizing GRK2 kinase and activating PI3K-AKT signaling pathwayA proteomic approach to elucidate the multiple targets of selenium-induced cell-growth inhibition in human lung cancer.eIF3: a factor for human health and disease.
P2860
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P2860
Identification of a 170-kDa protein over-expressed in lung cancers
description
2001 nî lūn-bûn
@nan
2001 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Identification of a 170-kDa protein over-expressed in lung cancers
@ast
Identification of a 170-kDa protein over-expressed in lung cancers
@en
Identification of a 170-kDa protein over-expressed in lung cancers
@nl
type
label
Identification of a 170-kDa protein over-expressed in lung cancers
@ast
Identification of a 170-kDa protein over-expressed in lung cancers
@en
Identification of a 170-kDa protein over-expressed in lung cancers
@nl
prefLabel
Identification of a 170-kDa protein over-expressed in lung cancers
@ast
Identification of a 170-kDa protein over-expressed in lung cancers
@en
Identification of a 170-kDa protein over-expressed in lung cancers
@nl
P2093
P2860
P356
P1476
Identification of a 170-kDa protein over-expressed in lung cancers
@en
P2093
P2860
P2888
P304
P356
10.1054/BJOC.2001.1828
P407
P577
2001-06-01T00:00:00Z
P5875
P6179
1020142586