Tubulin-interactive natural products as anticancer agents - Wikidata - awgldk - TriplyDB

Tubulin-interactive natural products as anticancer agents

Tubulin-interactive natural products as anticancer agents

http://www.wikidata.org/entity/Q24650163

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Enabling anticancer therapeutics by nanoparticle carriers: the delivery of Paclitaxel Zampanolide and dactylolide: cytotoxic tubulin-assembly agents and promising anticancer leads Discovery of new anticancer agents from higher plants Drug discovery prospect from untapped species: indications from approved natural product drugs Appraisals of Bangladeshi Medicinal Plants Used by Folk Medicine Practitioners in the Prevention and Management of Malignant Neoplastic Diseases Oblongifolin C inhibits metastasis by up-regulating keratin 18 and tubulins Laucysteinamide A, a Hybrid PKS/NRPS Metabolite from a Saipan Cyanobacterium, cf. Caldora penicillata.Synthesis and Cytotoxicity Evaluation of C4- and C5-Modified Analogues of the α,β-Unsaturated Lactone of Pironetin Synthesis and antiproliferative activities of ottelione a analogues Noscapine, a benzylisoquinoline alkaloid, sensitizes leukemic cells to chemotherapeutic agents and cytokines by modulating the NF-kappaB signaling pathway An efficient synthetic strategy for obtaining 4-methoxy carbon isotope labeled combretastatin A-4 phosphate and other Z-combretastatins.Microtubule-stabilizing drugs from marine sponges: focus on peloruside A and zampanolide Hemiasterlin analogues incorporating an aromatic, and heterocyclic type C-terminus: design, synthesis and biological evaluation.Streamlined syntheses of (-)-dictyostatin, 16-desmethyl-25,26-dihydrodictyostatin, and 6-epi-16-desmethyl-25,26-dihydrodictyostatin Salinosporamide natural products: Potent 20 S proteasome inhibitors as promising cancer chemotherapeutics.A Papaver somniferum 10-gene cluster for synthesis of the anticancer alkaloid noscapine.Antitumor agents. 284. New desmosdumotin B analogues with bicyclic B-ring as cytotoxic and antitubulin agents.Cabazitaxel: a novel second-line treatment for metastatic castration-resistant prostate cancer.A perspective on vascular disrupting agents that interact with tubulin: preclinical tumor imaging and biological assessment Synthesis of novel antimitotic agents based on 2-amino-3-aroyl-5-(hetero)arylethynyl thiophene derivatives A simplified synthesis of novel dictyostatin analogues with in vitro activity against epothilone B-resistant cells and antiangiogenic activity in zebrafish embryos Drugs that target dynamic microtubules: a new molecular perspective Bacterial symbionts and natural products.Ethyl acetate extract from marine sponge Hyattella cribriformis exhibit potent anticancer activity by promoting tubulin polymerization as evidenced mitotic arrest and induction of apoptosis.Efficient syntheses of 25,26-dihydrodictyostatin and 25,26-dihydro-6-epi-dictyostatin, two potent new microtubule-stabilizing agents.Bioactive substances with anti-neoplastic efficacy from marine invertebrates: Porifera and Coelenterata.Synthesis and evaluation of 1,5-disubstituted tetrazoles as rigid analogues of combretastatin A-4 with potent antiproliferative and antitumor activity.Discovery and optimization of a series of 2-aryl-4-amino-5-(3',4',5'-trimethoxybenzoyl)thiazoles as novel anticancer agents.Microtubule drugs: action, selectivity, and resistance across the kingdoms of life.Strategies for the Optimization of Natural Leads to Anticancer Drugs or Drug Candidates.Anti-angiogenic effects of the tubulysin precursor pretubulysin and of simplified pretubulysin derivatives.Synthesis and biological evaluation of 2-substituted-4-(3',4',5'-trimethoxyphenyl)-5-aryl thiazoles as anticancer agents.Eribulin for advanced breast cancer: a drug evaluation.Bisleuconothine A, a bisindole alkaloid, inhibits colorectal cancer cell in vitro and in vivo targeting Wnt signaling.New microtubule-inhibiting anticancer agents.Synthesis of isotopically labeled epothilones.Secondary metabolites of fungi from marine habitats.The medicinal potential of promising marine macrolides with anticancer activity.Eribulin: a novel cytotoxic chemotherapy agent.The antibody-drug conjugate: an enabling modality for natural product-based cancer therapeutics.

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P2860

Tubulin-interactive natural products as anticancer agents

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description

2009 nî lūn-bûn

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2009 թուականի Մարտին հրատարակուած գիտական յօդուած

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2009 թվականի մարտին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年论文

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name

Tubulin-interactive natural products as anticancer agents

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Tubulin-interactive natural products as anticancer agents

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Tubulin-interactive natural products as anticancer agents

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Tubulin-interactive natural products as anticancer agents

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Tubulin-interactive natural products as anticancer agents

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Tubulin-interactive natural products as anticancer agents

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Tubulin-interactive natural products as anticancer agents

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Tubulin-interactive natural products as anticancer agents

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Tubulin-interactive natural products as anticancer agents

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Tubulin-interactive natural products as anticancer agents

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David G I Kingston

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Multicentre phase II pharmacological evaluation of rhizoxin. Eortc early clinical studies (ECSG)/pharmacology and molecular mechanisms (PAMM) groups

Refined structure of alpha beta-tubulin at 3.5 A resolution

The primary antimitotic mechanism of action of the synthetic halichondrin E7389 is suppression of microtubule growth

A total synthesis of the antitumour macrolide rhizoxin D

Halichondrin B and homohalichondrin B, marine natural products binding in the vinca domain of tubulin. Discovery of tubulin-based mechanism of action by analysis of differential cytotoxicity data

Albumin-bound paclitaxel: a next-generation taxane

Natural products as sources of new drugs over the last 25 years

Epothilone B and its analogs - a new family of anticancer agents.

Natural products and combinatorial chemistry: back to the future.

Antineoplastic agents 389. New syntheses of the combretastatin A-4 prodrug.

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