Membrane-delimited coupling between sigma receptors and K+ channels in rat neurohypophysial terminals requires neither G-protein nor ATP
about
Sigma receptors: potential targets for a new class of antidepressant drugThe hallucinogen N,N-dimethyltryptamine (DMT) is an endogenous sigma-1 receptor regulatorAntagonist action of progesterone at σ-receptors in the modulation of voltage-gated sodium channelsAn unambiguous assay for the cloned human sigma1 receptor reveals high affinity interactions with dopamine D4 receptor selective compounds and a distinct structure-affinity relationship for butyrophenonesAntagonists show GTP-sensitive high-affinity binding to the sigma-1 receptorThe sigma receptor: evolution of the concept in neuropsychopharmacologyDynamic interaction between sigma-1 receptor and Kv1.2 shapes neuronal and behavioral responses to cocaineThe sigma-1 receptor is enriched in postsynaptic sites of C-terminals in mouse motoneurons. An anatomical and behavioral studySigma-1 Receptor Plays a Negative Modulation on N-type Calcium Channel.Sigma 1 receptor modulation of G-protein-coupled receptor signaling: potentiation of opioid transduction independent from receptor binding.The oligomeric states of the purified sigma-1 receptor are stabilized by ligands.Sigma-1 receptor antagonism restores injury-induced decrease of voltage-gated Ca2+ current in sensory neuronsTrace amines depress D(2)-autoreceptor-mediated responses on midbrain dopaminergic cells.Sigma-1 receptor agonists directly inhibit Nav1.2/1.4 channels.Sigma-2 receptor ligands and their perspectives in cancer diagnosis and therapy.Targeting sigma-1 receptor signaling by endogenous ligands for cardioprotection.Role of the Sigma-1 receptor in Amyotrophic Lateral Sclerosis (ALS)The sigma-1 receptors are present in monomeric and oligomeric forms in living cells in the presence and absence of ligandsLigand-dependent localization and intracellular stability of sigma-1 receptors in CHO-K1 cellsThe sigma-1 receptor binds to the Nav1.5 voltage-gated Na+ channel with 4-fold symmetry.The sigma-1 receptor: roles in neuronal plasticity and diseaseSigma1 receptors inhibit store-operated Ca2+ entry by attenuating coupling of STIM1 to Orai1Sigma receptors [σRs]: biology in normal and diseased statesVoltage-gated sodium channel modulation by sigma-receptors in cardiac myocytes and heterologous systems.Mu opioids and their receptors: evolution of a concept.The pharmacology of sigma-1 receptors.Pharmacology and therapeutic potential of sigma(1) receptor ligands.The sigma-1 receptor: a regulator of cancer cell electrical plasticity?The development of radiotracers for imaging sigma (σ) receptors in the central nervous system (CNS) using positron emission tomography (PET).Medicinal Chemistry of σ1 Receptor Ligands: Pharmacophore Models, Synthesis, Structure Affinity Relationships, and Pharmacological Applications.Sigma-1 receptors modulate neonatal Nav1.5 ion channels in breast cancer cell lines.Sigma 1 Receptor and Ion Channel Dynamics in Cancer.Structural Insights into Sigma1 Function.Sigma1 Pharmacology in the Context of Cancer.Demonstration of a direct interaction between sigma-1 receptors and acid-sensing ion channels.A direct interaction between the sigma-1 receptor and the hERG voltage-gated K+ channel revealed by atomic force microscopy and homogeneous time-resolved fluorescence (HTRF®).Purification and characterization of the guinea pig sigma-1 receptor functionally expressed in Escherichia coli.The sigma-1 receptor modulates NMDA receptor synaptic transmission and plasticity via SK channels in rat hippocampus.Apparent desensitization of the effects of sigma receptor ligand haloperidol in isolated rat and guinea pig hearts after chronic treatment.Sigma receptors inhibit high-voltage-activated calcium channels in rat sympathetic and parasympathetic neurons.
P2860
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P2860
Membrane-delimited coupling between sigma receptors and K+ channels in rat neurohypophysial terminals requires neither G-protein nor ATP
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2000 nî lūn-bûn
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2000 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
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2000 թվականի օգոստոսին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
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2000年論文
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2000年論文
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2000年論文
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Membrane-delimited coupling be ...... ires neither G-protein nor ATP
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Membrane-delimited coupling be ...... ires neither G-protein nor ATP
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Membrane-delimited coupling be ...... ires neither G-protein nor ATP
@nl
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Membrane-delimited coupling be ...... ires neither G-protein nor ATP
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Membrane-delimited coupling be ...... ires neither G-protein nor ATP
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Membrane-delimited coupling be ...... ires neither G-protein nor ATP
@nl
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Membrane-delimited coupling be ...... ires neither G-protein nor ATP
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Membrane-delimited coupling be ...... ires neither G-protein nor ATP
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Membrane-delimited coupling be ...... ires neither G-protein nor ATP
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P2093
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Membrane-delimited coupling be ...... ires neither G-protein nor ATP
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C P Palmer
M B Jackson
P J Lupardus
P2860
P304
P3181
P356
10.1111/J.1469-7793.2000.00527.X
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P478
P577
2000-08-01T00:00:00Z