about
Human CNK1 acts as a scaffold protein, linking Rho and Ras signal transduction pathwaysDensin-180, a synaptic protein, links to PSD-95 through its direct interaction with MAGUIN-1The scaffold protein CNK1 interacts with the tumor suppressor RASSF1A and augments RASSF1A-induced cell deathMeaningful relationships: the regulation of the Ras/Raf/MEK/ERK pathway by protein interactionsThe RAS effector RIN1 directly competes with RAF and is regulated by 14-3-3 proteins.Synaptic localization of membrane-associated guanylate kinase-interacting protein mediated by the pleckstrin homology domainDrosophila-raf acts to elaborate dorsoventral pattern in the ectoderm of developing embryosCoordinating ERK/MAPK signalling through scaffolds and inhibitorsBioluminescence resonance energy transfer identify scaffold protein CNK1 interactions in intact cells.The CNK1 scaffold binds cytohesins and promotes insulin pathway signaling.Apical accumulation of the Sevenless receptor tyrosine kinase during Drosophila eye development is promoted by the small GTPase Rap1CNK1 is a scaffold protein that regulates Src-mediated Raf-1 activation.The novel SAM domain protein Aveugle is required for Raf activation in the Drosophila EGF receptor signaling pathwayA genetic screen for modifiers of a kinase suppressor of Ras-dependent rough eye phenotype in Drosophila.KSR is a scaffold required for activation of the ERK/MAPK module.Loss-of-Function CNKSR2 Mutation Is a Likely Cause of Non-Syndromic X-Linked Intellectual Disability.Adult and larval photoreceptors use different mechanisms to specify the same Rhodopsin fatesBimodal regulation of RAF by CNK in Drosophila.p53-regulated transcriptional program associated with genotoxic stress-induced apoptosis.DroVav, the Drosophila melanogaster homologue of the mammalian Vav proteins, serves as a signal transducer protein in the Rac and DER pathways.Ca-dependent Ras/Erk signaling mediates negative selection of autoreactive B cells.Ras effector switching as a developmental strategy.
P2860
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P2860
description
1999 nî lūn-bûn
@nan
1999 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Functional analysis of CNK in RAS signaling
@ast
Functional analysis of CNK in RAS signaling
@en
Functional analysis of CNK in RAS signaling
@nl
type
label
Functional analysis of CNK in RAS signaling
@ast
Functional analysis of CNK in RAS signaling
@en
Functional analysis of CNK in RAS signaling
@nl
prefLabel
Functional analysis of CNK in RAS signaling
@ast
Functional analysis of CNK in RAS signaling
@en
Functional analysis of CNK in RAS signaling
@nl
P2093
P2860
P356
P1476
Functional analysis of CNK in RAS signaling
@en
P2093
P2860
P304
P356
10.1073/PNAS.96.23.13259
P407
P577
1999-11-09T00:00:00Z