Cytoplasmic dynein/dynactin drives kinetochore protein transport to the spindle poles and has a role in mitotic spindle checkpoint inactivation - Wikidata - awgldk - TriplyDB

Cytoplasmic dynein/dynactin drives kinetochore protein transport to the spindle poles and has a role in mitotic spindle checkpoint inactivation

Cytoplasmic dynein/dynactin drives kinetochore protein transport to the spindle poles and has a role in mitotic spindle checkpoint inactivation

http://www.wikidata.org/entity/Q24652311

about

Caenorhabditis elegans cyclin B3 is required for multiple mitotic processes including alleviation of a spindle checkpoint-dependent block in anaphase chromosome segregation The DYNLT3 light chain directly links cytoplasmic dynein to a spindle checkpoint protein, Bub3 Crystal structure of the tetrameric Mad1-Mad2 core complex: implications of a 'safety belt' binding mechanism for the spindle checkpoint Nucleoporin translocated promoter region (Tpr) associates with dynein complex, preventing chromosome lagging formation during mitosis.Zwilch, a new component of the ZW10/ROD complex required for kinetochore functions ZW10 links mitotic checkpoint signaling to the structural kinetochore.CLASP1, astrin and Kif2b form a molecular switch that regulates kinetochore-microtubule dynamics to promote mitotic progression and fidelity Silencing mitosin induces misaligned chromosomes, premature chromosome decondensation before anaphase onset, and mitotic cell death.Structural analysis reveals features of the spindle checkpoint kinase Bub1-kinetochore subunit Knl1 interaction Shugoshin is a Mad1/Cdc20-like interactor of Mad2 Cyclin B1 is localized to unattached kinetochores and contributes to efficient microtubule attachment and proper chromosome alignment during mitosis Determinants of conformational dimerization of Mad2 and its inhibition by p31comet The kinetochore protein, CENPF, is mutated in human ciliopathy and microcephaly phenotypes Dynein light intermediate chain 1 is required for progress through the spindle assembly checkpoint.Mitotic control of kinetochore-associated dynein and spindle orientation by human Spindly Probing the in vivo function of Mad1:C-Mad2 in the spindle assembly checkpoint Implication of ZW10 in membrane trafficking between the endoplasmic reticulum and Golgi Ubiquitylation-dependent localization of PLK1 in mitosis Mitosin/CENP-F is a conserved kinetochore protein subjected to cytoplasmic dynein-mediated poleward transport Fcp1-dependent dephosphorylation is required for M-phase-promoting factor inactivation at mitosis exit Human Nudel and NudE as regulators of cytoplasmic dynein in poleward protein transport along the mitotic spindle EB1 targets to kinetochores with attached, polymerizing microtubules A mammalian NudC-like protein essential for dynein stability and cell viability Hec1 and nuf2 are core components of the kinetochore outer plate essential for organizing microtubule attachment sites.Linking kinetochore-microtubule binding to the spindle checkpoint Kinetochore dynein is required for chromosome motion and congression independent of the spindle checkpoint Stable hZW10 kinetochore residency, mediated by hZwint-1 interaction, is essential for the mitotic checkpoint ZW10 function in mitotic checkpoint control, dynein targeting and membrane trafficking: is dynein the unifying theme?Rapid microtubule-independent dynamics of Cdc20 at kinetochores and centrosomes in mammalian cells hNuf2 inhibition blocks stable kinetochore-microtubule attachment and induces mitotic cell death in HeLa cells Nudel functions in membrane traffic mainly through association with Lis1 and cytoplasmic dynein Spindly, a novel protein essential for silencing the spindle assembly checkpoint, recruits dynein to the kinetochore Role of the kinetochore/cell cycle checkpoint protein ZW10 in interphase cytoplasmic dynein function Dynein/dynactin regulate metaphase spindle length by targeting depolymerizing activities to spindle poles.Small RAB GTPases Regulate Multiple Steps of Mitosis The multifaceted roles of the HORMA domain in cellular signaling Moonlighting functions of the NRZ (mammalian Dsl1) complex The spindle checkpoint and chromosome segregation in meiosis The Renaissance or the cuckoo clock The current view for the silencing of the spindle assembly checkpoint

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P2860

Cytoplasmic dynein/dynactin drives kinetochore protein transport to the spindle poles and has a role in mitotic spindle checkpoint inactivation

http://www.wikidata.org/entity/Q24652311

description

2001 nî lūn-bûn

@nan

2001 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2001 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

2001年の論文

@ja

2001年論文

@yue

2001年論文

@zh-hant

2001年論文

@zh-hk

2001年論文

@zh-mo

2001年論文

@zh-tw

2001年论文

@wuu

name

Cytoplasmic dynein/dynactin dr ...... pindle checkpoint inactivation

@ast

Cytoplasmic dynein/dynactin dr ...... pindle checkpoint inactivation

@en

Cytoplasmic dynein/dynactin dr ...... pindle checkpoint inactivation

@nl

type

label

Cytoplasmic dynein/dynactin dr ...... pindle checkpoint inactivation

@ast

Cytoplasmic dynein/dynactin dr ...... pindle checkpoint inactivation

@en

Cytoplasmic dynein/dynactin dr ...... pindle checkpoint inactivation

@nl

prefLabel

Cytoplasmic dynein/dynactin dr ...... pindle checkpoint inactivation

@ast

Cytoplasmic dynein/dynactin dr ...... pindle checkpoint inactivation

@en

Cytoplasmic dynein/dynactin dr ...... pindle checkpoint inactivation

@nl

P1433

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P2860

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P1433

Journal of Cell Biology

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Cytoplasmic dynein/dynactin dr ...... pindle checkpoint inactivation

@en

P2093

B F McEwen

http://www.w3.org/2001/XMLSchema#string

B J Howell

http://www.w3.org/2001/XMLSchema#string

C L Rieder

http://www.w3.org/2001/XMLSchema#string

D B Hoffman

http://www.w3.org/2001/XMLSchema#string

E D Salmon

http://www.w3.org/2001/XMLSchema#string

E M Farrar

http://www.w3.org/2001/XMLSchema#string

J C Canman

http://www.w3.org/2001/XMLSchema#string

P2860

A role for the lissencephaly gene LIS1 in mitosis and cytoplasmic dynein function

Human Zw10 and ROD are mitotic checkpoint proteins that bind to kinetochores

Identification of a human mitotic checkpoint gene: hsMAD2

Conservation of the centromere/kinetochore protein ZW10

Molecular characterization of the 50-kD subunit of dynactin reveals function for the complex in chromosome alignment and spindle organization during mitosis

Cytoplasmic dynein plays a role in mammalian mitotic spindle formation

ZW10 helps recruit dynactin and dynein to the kinetochore

Microtubule-dependent changes in assembly of microtubule motor proteins and mitotic spindle checkpoint proteins at PtK1 kinetochores

A new look at kinetochore structure in vertebrate somatic cells using high-pressure freezing and freeze substitution

Mammalian mad2 and bub1/bubR1 recognize distinct spindle-attachment and kinetochore-tension checkpoints

P304

1159-72

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P31

scholarly article

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2278260

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P356

10.1083/JCB.200105093

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P407

P433

7

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P478

155

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P577

2001-12-24T00:00:00Z

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P5875

11602100

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P698

11756470

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P921

P932

2199338

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