5'-triphosphate RNA requires base-paired structures to activate antiviral signaling via RIG-I - Wikidata - awgldk - TriplyDB

5'-triphosphate RNA requires base-paired structures to activate antiviral signaling via RIG-I

5'-triphosphate RNA requires base-paired structures to activate antiviral signaling via RIG-I

http://www.wikidata.org/entity/Q24653786

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Innate immune suppression enables frequent transfection with RNA encoding reprogramming proteins ZAPS is a potent stimulator of signaling mediated by the RNA helicase RIG-I during antiviral responses DDX60, a DEXD/H box helicase, is a novel antiviral factor promoting RIG-I-like receptor-mediated signaling SF1 and SF2 helicases: family matters Paramyxovirus V proteins interact with the RNA Helicase LGP2 to inhibit RIG-I-dependent interferon induction Function and regulation of retinoic acid-inducible gene-I LGP2 is a positive regulator of RIG-I- and MDA5-mediated antiviral responses Cytosolic Innate Immune Sensing and Signaling upon Infection Rotavirus non-structural proteins: structure and function RNAs Containing Modified Nucleotides Fail To Trigger RIG-I Conformational Changes for Innate Immune Signaling Ebolavirus VP35 uses a bimodal strategy to bind dsRNA for innate immune suppression Structural basis for dsRNA recognition and interferon antagonism by Ebola VP35 Structural and functional insights into 5′-ppp RNA pattern recognition by the innate immune receptor RIG-I The Structural Basis of 5′ Triphosphate Double-Stranded RNA Recognition by RIG-I C-Terminal Domain Crystal structure of RIG-I C-terminal domain bound to blunt-ended double-strand RNA without 5' triphosphate Crystallographic Analysis of Rotavirus NSP2-RNA Complex Reveals Specific Recognition of 5' GG Sequence for RTPase Activity Structures of Arenaviral Nucleoproteins with Triphosphate dsRNA Reveal a Unique Mechanism of Immune Suppression Defining the functional determinants for RNA surveillance by RIG-I Crystal and solution structure of the human RIG-I SF2 domain Emerging Roles of Protein Deamidation in Innate Immune Signaling RIG-I in RNA virus recognition LGP2 synergy with MDA5 in RLR-mediated RNA recognition and antiviral signaling Influenza virus activation of the interferon system Induction of type I interferon by RNA viruses: cellular receptors and their substrates Pathogen recognition by the innate immune system 5'PPP-RNA induced RIG-I activation inhibits drug-resistant avian H5N1 as well as 1918 and 2009 pandemic influenza virus replication.Sequence-non-specific effects of RNA interference triggers and microRNA regulators.Association of RIG-I with innate immunity of ducks to influenza Small non-coding RNAs encoded within the herpes simplex virus type 1 latency associated transcript (LAT) cooperate with the retinoic acid inducible gene I (RIG-I) to induce beta-interferon promoter activity and promote cell survival.Impaired cellular responses to cytosolic DNA or infection with Listeria monocytogenes and vaccinia virus in the absence of the murine LGP2 protein.Unpaired 5' ppp-nucleotides, as found in arenavirus double-stranded RNA panhandles, are not recognized by RIG-I Incoming RNA virus nucleocapsids containing a 5'-triphosphorylated genome activate RIG-I and antiviral signaling Human neuronal cells possess functional cytoplasmic and TLR-mediated innate immune pathways influenced by phosphatidylinositol-3 kinase signaling.Negative role of RIG-I serine 8 phosphorylation in the regulation of interferon-beta production.Influenza A virus-generated small RNAs regulate the switch from transcription to replication.Immunomodulatory effects of dsRNA and its potential as vaccine adjuvant.A common polymorphism in the caspase recruitment domain of RIG-I modifies the innate immune response of human dendritic cells Recognition of virus infection and innate host responses to viral gene therapy vectors.Preference of RIG-I for short viral RNA molecules in infected cells revealed by next-generation sequencing.RIG-I-mediated antiviral signaling is inhibited in HIV-1 infection by a protease-mediated sequestration of RIG-I.

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5'-triphosphate RNA requires base-paired structures to activate antiviral signaling via RIG-I

http://www.wikidata.org/entity/Q24653786

description

2009 nî lūn-bûn

@nan

2009 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի հուլիսին հրատարակված գիտական հոդված

@hy

2009年の論文

@ja

2009年論文

@yue

2009年論文

@zh-hant

2009年論文

@zh-hk

2009年論文

@zh-mo

2009年論文

@zh-tw

2009年论文

@wuu

name

5'-triphosphate RNA requires b ...... antiviral signaling via RIG-I

@ast

5'-triphosphate RNA requires b ...... antiviral signaling via RIG-I

@en

5'-triphosphate RNA requires b ...... antiviral signaling via RIG-I

@nl

type

label

5'-triphosphate RNA requires b ...... antiviral signaling via RIG-I

@ast

5'-triphosphate RNA requires b ...... antiviral signaling via RIG-I

@en

5'-triphosphate RNA requires b ...... antiviral signaling via RIG-I

@nl

prefLabel

5'-triphosphate RNA requires b ...... antiviral signaling via RIG-I

@ast

5'-triphosphate RNA requires b ...... antiviral signaling via RIG-I

@en

5'-triphosphate RNA requires b ...... antiviral signaling via RIG-I

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Proceedings of the National Academy of Sciences of the United States of America

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5'-triphosphate RNA requires b ...... antiviral signaling via RIG-I

@en

P2093

Andreas Schmidt

http://www.w3.org/2001/XMLSchema#string

Franziska S Hoffmann

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Johannes C Hellmuth

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Marie-Cecile Michallet

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Michael Wenzel

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Robert Besch

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Simon Rothenfusser

http://www.w3.org/2001/XMLSchema#string

Stefan Endres

http://www.w3.org/2001/XMLSchema#string

Tobias Schwerd

http://www.w3.org/2001/XMLSchema#string

Wolfgang Hamm

http://www.w3.org/2001/XMLSchema#string

P2860

Sequence-specific potent induction of IFN-alpha by short interfering RNA in plasmacytoid dendritic cells through TLR7

The C-terminal regulatory domain is the RNA 5'-triphosphate sensor of RIG-I

Mfold web server for nucleic acid folding and hybridization prediction

Regulating intracellular antiviral defense and permissiveness to hepatitis C virus RNA replication through a cellular RNA helicase, RIG-I

The V proteins of paramyxoviruses bind the IFN-inducible RNA helicase, mda-5, and inhibit its activation of the IFN-beta promoter

Innate immunity induced by composition-dependent RIG-I recognition of hepatitis C virus RNA

Length-dependent recognition of double-stranded ribonucleic acids by retinoic acid-inducible gene-I and melanoma differentiation-associated gene 5

Agonist and Antagonist Recognition by RIG-I, a Cytoplasmic Innate Immunity Receptor

Nonself RNA-sensing mechanism of RIG-I helicase and activation of antiviral immune responses

Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses

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12067-72

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scholarly article

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3446431

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10.1073/PNAS.0900971106

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29

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106

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Karl-Peter Hopfner

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2009-07-21T00:00:00Z

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26337962

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19574455

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