Identification of heme as the ligand for the orphan nuclear receptors REV-ERBalpha and REV-ERBbeta.
about
Identification of an endogenous ligand bound to a native orphan nuclear receptorIn situ proteolysis to generate crystals for structure determination: an updateHeme controls the regulation of protein tyrosine kinases Jak2 and SrcDBC1 (Deleted in Breast Cancer 1) modulates the stability and function of the nuclear receptor Rev-erbαThe nuclear receptor Rev-erbalpha is a liver X receptor (LXR) target gene driving a negative feedback loop on select LXR-induced pathways in human macrophagesModulation of retinoic acid receptor-related orphan receptor alpha and gamma activity by 7-oxygenated sterol ligandsA circadian clock in hippocampus is regulated by interaction between oligophrenin-1 and Rev-erbαRegulation of circadian behaviour and metabolism by synthetic REV-ERB agonistsBeyond the monoaminergic hypothesis: neuroplasticity and epigenetic changes in a transgenic mouse model of depressionIdentification of Escherichia coli HemG as a novel, menadione-dependent flavodoxin with protoporphyrinogen oxidase activityStructure of the intact PPAR-gamma-RXR- nuclear receptor complex on DNABile acids: regulation of synthesisInterdependence of nutrient metabolism and the circadian clock system: Importance for metabolic healthReciprocal Control of the Circadian Clock and Cellular Redox State - a Critical AppraisalInsights into Orphan Nuclear Receptors as Prognostic Markers and Novel Therapeutic Targets for Breast CancerNuclear Receptors, RXR, and the Big BangBreast cancer and circadian disruption from electric lighting in the modern worldRoad to exercise mimetics: targeting nuclear receptors in skeletal muscleRegulation of metabolism: the circadian clock dictates the timeElectric light, particularly at night, disrupts human circadian rhythmicity: is that a problem?ROR nuclear receptors: structures, related diseases, and drug discoveryPharmacological modulators of the circadian clock as potential therapeutic drugs: focus on genotoxic/anticancer therapyThe circadian clock regulates autophagy directly through the nuclear hormone receptor Nr1d1/Rev-erbα and indirectly via Cebpb/(C/ebpβ) in zebrafish.The Structural Basis of Gas-Responsive Transcription by the Human Nuclear Hormone Receptor REV-ERBβStructure of Rev-erbα bound to N-CoR reveals a unique mechanism of nuclear receptor–co-repressor interactionStructure of REV-ERB Ligand-binding Domain Bound to a Porphyrin AntagonistNegative feedback maintenance of heme homeostasis by its receptor, Rev-erbalphaNuclear receptor Rev-erbalpha: a heme receptor that coordinates circadian rhythm and metabolismCharacterization of the core mammalian clock component, NPAS2, as a REV-ERBalpha/RORalpha target geneDirect regulation of CLOCK expression by REV-ERB.Heme dynamics and trafficking factors revealed by genetically encoded fluorescent heme sensors.A fly's view of neuronal remodelingTherapeutic Effect of a Synthetic RORα/γ Agonist in an Animal Model of AutismCircadian regulation of metabolismCircadian rhythms in liver metabolism and diseaseNovel role of nuclear receptor Rev-erbα in hepatic stellate cell activation: potential therapeutic target for liver injuryLigand modulation of REV-ERBalpha function resets the peripheral circadian clock in a phasic mannerThe mammalian clock component PERIOD2 coordinates circadian output by interaction with nuclear receptorsImaging of heme/hemeproteins in nucleus of the living cells expressing heme-binding nuclear receptorsWhat are nuclear receptor ligands?
P2860
Q21091201-84B04F29-E263-41B3-8A0A-19E1A41D7758Q21562460-A0FCA1B7-BFC8-4F2C-AE81-6BAB0736129FQ24305018-665938B3-B91C-4E12-BFE5-A94340E0D637Q24316107-5352981A-192B-4A66-A0B5-A4C1EE7FEE31Q24317341-F1EF7BE0-A65E-42E8-8404-6182C75AB5B3Q24336344-7700086F-FAAD-41AC-885C-80797C045AAEQ24336512-A207BCE4-B3F9-4ED3-9A93-B66B540B606FQ24629345-7A1E7A5D-9CE4-4B96-BB81-58BB53D68AD5Q24629465-FBD99C5B-5B91-475A-B070-6CA6892F3E22Q24648730-158AB25A-6BE9-4B24-A500-A9BC29D762D8Q24655111-17C94229-2D82-4283-8AD0-0531F5DC4101Q24658139-A0CEDA7D-9D30-43BE-B732-1FB7CF24BC03Q26765492-06464178-B14B-41E1-84E1-42AA5A68D061Q26774796-23669DE4-292F-4EF5-B2C7-E906A3A088E4Q26795488-718CB97F-E229-4091-8B6F-E543FB311014Q26821789-61BA1E9C-0983-4CA1-B555-11C4A9455AEAQ26823410-E6F11D95-70E3-4B26-8FD2-E7DEDE1CD1EAQ26825855-EFEF5CFC-D45D-4F08-B4FA-95AF44CE2123Q26829935-EE64F19C-1E60-412B-B1F8-D888AB2A6DC1Q26830662-641E1158-EF69-45CF-A875-1A3F117525E1Q26861208-7DC0EBC4-C14E-401B-97E1-5BD120E90B05Q26864230-BEC6F9F5-4B57-4750-8B31-3A2A5793220EQ27311237-8354F56A-06DA-4753-8DF4-23295F3FD2CFQ27653944-C881B126-9FF7-4EE6-AF27-CF59974329BDQ27662827-6DF1D3BC-5A60-4E12-8E6F-4201F59BA8C5Q27683978-1A855856-A8DE-4FAB-B477-3C4E73890B7CQ27865238-E9C15376-99F5-4786-8563-178B6D1B0B17Q27865249-24D0895F-2353-4C76-90C2-31E391D9DE7BQ27865255-7BE424F6-4282-4219-A6DC-0F4F5E500CD8Q27865257-2C3A525F-2E4C-4F13-92C4-03F326E511C4Q27929826-FBDBB28B-99DF-431D-AAB3-9FBA93268113Q28068381-3C991505-3E99-4E73-8BC2-2023318C7D60Q28387385-45D12DBD-79C7-4204-9282-91FC8F80CC2CQ28390852-DF63E6FB-576D-4A60-A141-FBE1395580D8Q28392853-5E26C347-3859-4D4E-BC6C-C01F801B6162Q28564897-6BBF8B8F-BE6D-4B32-A348-161BA4E21520Q28582355-6B27F95A-DFA5-4E64-B002-5CF0A1A7A217Q28589192-8C457C6C-44D1-4900-BA88-10CE638D861CQ28594319-70B6E7D8-9617-4C5D-8D30-6A73BA863BBAQ28743958-2EA8B07A-F7A4-4EB8-B53E-1D6FD86155C9
P2860
Identification of heme as the ligand for the orphan nuclear receptors REV-ERBalpha and REV-ERBbeta.
description
2007 nî lūn-bûn
@nan
2007 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Identification of heme as the ...... s REV-ERBalpha and REV-ERBbeta
@nl
Identification of heme as the ...... REV-ERBalpha and REV-ERBbeta.
@ast
Identification of heme as the ...... REV-ERBalpha and REV-ERBbeta.
@en
type
label
Identification of heme as the ...... s REV-ERBalpha and REV-ERBbeta
@nl
Identification of heme as the ...... REV-ERBalpha and REV-ERBbeta.
@ast
Identification of heme as the ...... REV-ERBalpha and REV-ERBbeta.
@en
prefLabel
Identification of heme as the ...... s REV-ERBalpha and REV-ERBbeta
@nl
Identification of heme as the ...... REV-ERBalpha and REV-ERBbeta.
@ast
Identification of heme as the ...... REV-ERBalpha and REV-ERBbeta.
@en
P2093
P2860
P3181
P356
P1476
Identification of heme as the ...... REV-ERBalpha and REV-ERBbeta.
@en
P2093
Amanda K Nosie
Don B McClure
Fraydoon Rastinejad
Keith R Stayrook
Lorri L Burris
Pamela M Rogers
Pengxiang Huang
Sepideh Khorasanizadeh
Srilatha Raghuram
Thomas P Burris
P2860
P2888
P304
P3181
P356
10.1038/NSMB1344
P407
P577
2007-11-25T00:00:00Z
P5875
P6179
1025305784