Solution structure of a de novo protein from a designed combinatorial library
about
De novo proteins from designed combinatorial librariesGetting specificity from simplicity in putative proteins from the prebiotic EarthStructure and dynamics of de novo proteins from a designed superfamily of 4-helix bundlesComputer-Based Redesign of a β Sandwich Protein Suggests that Extensive Negative Design Is Not Required for De Novo β Sheet DesignOrigin of a folded repeat protein from an intrinsically disordered ancestorSearching for folded proteins in vitro and in silico.Computational de novo design of a four-helix bundle protein--DND_4HB.Sequence periodicity and secondary structure propensity in model proteins.Flexible Proteins at the Origin of Life.A man-made ATP-binding protein evolved independent of nature causes abnormal growth in bacterial cellsDesign of bioactive and structurally well-defined peptides from conformationally restricted libraries.An intein-based genetic selection allows the construction of a high-quality library of binary patterned de novo protein sequences.Combinatorial approaches to protein stability and structure.The NMR structure of the murine DLC2 SAM domain reveals a variant fold that is similar to a four-helix bundlePeroxidase activity of de novo heme proteins immobilized on electrodes.Selection and structural analysis of de novo proteins from an alpha3beta3 genetic library.De novo designed proteins from a library of artificial sequences function in Escherichia coli and enable cell growthBinding of small molecules to cavity forming mutants of a de novo designed protein.Directed evolution of the peroxidase activity of a de novo-designed protein.The use of MALDI-TOF-MS and in silico studies for determination of antimicrobial peptides' affinity to bacterial cells.Design, expression, and purification of de novo transmembrane "hairpin" peptides.Common attributes of native-state structures of proteins, disordered proteins, and amyloid.Proteins from an unevolved library of de novo designed sequences bind a range of small molecules.An evolution-based approach to De Novo protein design and case study on Mycobacterium tuberculosis.Relative stability of de novo four-helix bundle proteins: insights from coarse grained molecular simulations.Generic hydrophobic residues are sufficient to promote aggregation of the Alzheimer's Abeta42 peptide.De Novo Proteins with Life-Sustaining Functions Are Structurally DynamicFunctional engineered channels and pores (Review).A de novo protein confers copper resistance in Escherichia coli.A protein constructed de novo enables cell growth by altering gene regulation.Manipulating cofactor binding thermodynamics in an artificial oxygen transport protein.Cofactor binding and enzymatic activity in an unevolved superfamily of de novo designed 4-helix bundle proteins.An enzymatic molten globule: efficient coupling of folding and catalysis.Constructing manmade enzymes for oxygen activation.Generic coarse-grained model for protein folding and aggregation.Hierarchical design of artificial proteins and complexes toward synthetic structural biology.Sequence dependent aggregation of peptides and fibril formation.Simple bioseparations using self-cleaving elastin-like polypeptide tags.Geometry of proteins: hydrogen bonding, sterics, and marginally compact tubes.7 Computational protein design and discovery
P2860
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P2860
Solution structure of a de novo protein from a designed combinatorial library
description
2003 nî lūn-bûn
@nan
2003 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Solution structure of a de novo protein from a designed combinatorial library
@ast
Solution structure of a de novo protein from a designed combinatorial library
@en
Solution structure of a de novo protein from a designed combinatorial library
@nl
type
label
Solution structure of a de novo protein from a designed combinatorial library
@ast
Solution structure of a de novo protein from a designed combinatorial library
@en
Solution structure of a de novo protein from a designed combinatorial library
@nl
prefLabel
Solution structure of a de novo protein from a designed combinatorial library
@ast
Solution structure of a de novo protein from a designed combinatorial library
@en
Solution structure of a de novo protein from a designed combinatorial library
@nl
P2093
P2860
P3181
P356
P1476
Solution structure of a de novo protein from a designed combinatorial library
@en
P2093
David Fela
Michael H Hecht
P2860
P304
P3181
P356
10.1073/PNAS.1835644100
P407
P577
2003-11-11T00:00:00Z