Vascular endothelial growth factor-D is an independent prognostic factor in epithelial ovarian carcinoma - Wikidata - awgldk - TriplyDB

Vascular endothelial growth factor-D is an independent prognostic factor in epithelial ovarian carcinoma

Vascular endothelial growth factor-D is an independent prognostic factor in epithelial ovarian carcinoma

http://www.wikidata.org/entity/Q24656802

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Vascular endothelial growth factor (VEGF)-D and VEGF-A differentially regulate KDR-mediated signaling and biological function in vascular endothelial cells Plasmin activates the lymphangiogenic growth factors VEGF-C and VEGF-D Beta-catenin inversely regulates vascular endothelial growth factor-D mRNA stability Clinical implication of expression of cyclooxygenase-2 and peroxisome proliferator activated-receptor gamma in epithelial ovarian tumours Antiangiogenic gene therapy with soluble VEGFR-1, -2, and -3 reduces the growth of solid human ovarian carcinoma in mice Serum VEGFR-3 and survival of advanced gastric cancer patients treated with FOLFOX.VEGFR3 inhibition chemosensitizes ovarian cancer stemlike cells through down-regulation of BRCA1 and BRCA2.Prognostic biomarkers in ovarian cancer.4-Methylumbelliferone inhibits ovarian cancer growth by suppressing thymidine phosphorylase expression VEGF-D-induced draining lymphatic enlargement and tumor lymphangiogenesis promote lymph node metastasis in a xenograft model of ovarian carcinoma Expression of lymphangiogenic factors and evidence of intratumoral lymphangiogenesis in pancreatic endocrine tumors.Distinct roles of vascular endothelial growth factor-D in lymphangiogenesis and metastasis.The connection between lymphangiogenic signalling and prostaglandin biology: a missing link in the metastatic pathway.Targeting lymphangiogenesis to prevent tumour metastasis The role of the VEGF-C/VEGFRs axis in tumor progression and therapy.The balance of VEGF-C and VEGFR-3 mRNA is a predictor of lymph node metastasis in non-small cell lung cancer.Angiogenesis in cancer.Vascular endothelial growth factor receptor-3 promotes breast cancer cell proliferation, motility and survival in vitro and tumor formation in vivo.Correlation of vascular endothelial growth factor-D expression and VEGFR-3-positive vessel density with lymph node metastasis in gastric carcinoma.VEGF-D expression correlates with colorectal cancer aggressiveness and is downregulated by cetuximab.Differential Receptor Binding and Regulatory Mechanisms for the Lymphangiogenic Growth Factors Vascular Endothelial Growth Factor (VEGF)-C and -D.Intratumoural chemotherapy of lung cancer for diagnosis and treatment of draining lymph node metastasis.Lymphatic density and metastatic spread in human malignant melanoma.Signaling for lymphangiogenesis via VEGFR-3 is required for the early events of metastasis.Inhibition of lymphatic metastasis in neuroblastoma by a novel neutralizing antibody to vascular endothelial growth factor-D.Antiangiogenic gene therapy with soluble VEGF-receptors -1, -2 and -3 together with paclitaxel prolongs survival of mice with human ovarian carcinoma.Rapamycin, a specific inhibitor of the mammalian target of rapamycin, suppresses lymphangiogenesis and lymphatic metastasis.Primary and metastatic ovarian cancer: Characterization by 3.0T diffusion-weighted MRI.Decreased serum vascular endothelial growth factor-D levels in metastatic patients with differentiated thyroid carcinoma.Expression of VEGF-D in epithelial ovarian cancer and its relationship to lymphatic metastasis.Expression of VEGF-C, VEGF-D and their receptor VEGFR-3 in diffuse large B-cell lymphomas.Emerging Roles for VEGF-D in Human Disease.The prognostic significance of VEGF-C and VEGF-A in non-Hodgkin lymphomas.Transcription of the vascular endothelial growth factor receptor-3 (VEGFR3) gene is regulated by the zinc finger proteins Sp1 and Sp3 and is under epigenetic control: transcription of vascular endothelial growth factor receptor 3.A gene signature combining the tissue expression of three angiogenic factors is a prognostic marker in early-stage non-small cell lung cancer.Vascular endothelial growth factor-D: signaling mechanisms, biology, and clinical relevance.

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Vascular endothelial growth factor-D is an independent prognostic factor in epithelial ovarian carcinoma

http://www.wikidata.org/entity/Q24656802

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British Journal of Cancer

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Vascular endothelial growth fa ...... n epithelial ovarian carcinoma

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C M Holland

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D Licence

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D S Charnock-Jones

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H Mizunuma

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J M Hastings

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M Emoto

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M Umemoto

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S Sato

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T Sakamoto

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P2860

Vascular endothelial growth factor D (VEGF-D) is a ligand for the tyrosine kinases VEGF receptor 2 (Flk1) and VEGF receptor 3 (Flt4)

A novel vascular endothelial growth factor, VEGF-C, is a ligand for the Flt4 (VEGFR-3) and KDR (VEGFR-2) receptor tyrosine kinases

Proteolytic processing regulates receptor specificity and activity of VEGF-C.

Identification of a c-fos-induced gene that is related to the platelet-derived growth factor/vascular endothelial growth factor family

Carbonyl reductase as a significant predictor of survival and lymph node metastasis in epithelial ovarian cancer

VEGF-D promotes the metastatic spread of tumor cells via the lymphatics

Vascular endothelial growth factor-C-mediated lymphangiogenesis promotes tumour metastasis.

The specificity of receptor binding by vascular endothelial growth factor-d is different in mouse and man

Hyperplasia of lymphatic vessels in VEGF-C transgenic mice

Angiogenesis in cancer, vascular, rheumatoid and other disease

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237-44

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10.1038/SJ.BJC.6600701

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2

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88

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Atsushi Yanaihara

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2003-01-27T00:00:00Z

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10878623

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1005851311

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12610509

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2377043

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