Single-nucleotide polymorphisms in the p53 pathway regulate fertility in humans - Wikidata - awgldk - TriplyDB

Single-nucleotide polymorphisms in the p53 pathway regulate fertility in humans

Single-nucleotide polymorphisms in the p53 pathway regulate fertility in humans

http://www.wikidata.org/entity/Q24658392

about

The first 30 years of p53: growing ever more complex Biomarkers in reproductive medicine: the promise, and can it be fulfilled?Cancer susceptibility and reproductive trade-offs: a model of the evolution of cancer defences Evolutionary medicine: its scope, interest and potential The emergence of human-evolutionary medical genomics Genome-Wide Association Mapping for Female Infertility in Inbred Mice.Germline mutations and polymorphisms in the origins of cancers in women.Drosophila foxo acts in males to cause sexual-dimorphism in tissue-specific p53 life span effects.Drosophila melanogaster p53 has developmental stage-specific and sex-specific effects on adult life span indicative of sexual antagonistic pleiotropy.TP53 mutations in human cancers: origins, consequences, and clinical use No association of the p53 codon 72 polymorphism with malaria in Ghanaian primiparae and Rwandan children.Single-nucleotide polymorphisms in the p53 signaling pathway.The origins and evolution of the p53 family of genes.Impact papers on aging in 2009.The role of p53 gene family in reproduction.The p53 orchestra: Mdm2 and Mdmx set the tone p53 at a glance.Minireview: Steroid-regulated paracrine mechanisms controlling implantation How contemporary human reproductive behaviors influence the role of fertility-related genes: the example of the p53 gene.Single-nucleotide polymorphisms in p53 pathway and aggressiveness of prostate cancer in a Caucasian population.LIF negatively regulates tumour-suppressor p53 through Stat3/ID1/MDM2 in colorectal cancers.p53 codon 72 polymorphism and hematological cancer risk: an update meta-analysis Population distribution and ancestry of the cancer protective MDM2 SNP285 (rs117039649).The codon 72 polymorphism of p53 regulates interaction with NF-{kappa}B and transactivation of genes involved in immunity and inflammation Regulation of female reproduction by p53 and its family members Regulation of Fertility by the p53 Family Members.C. elegans CEP-1/p53 and BEC-1 are involved in DNA repair.Regulation of p53 function by lysine methylation.The TP73 gene polymorphism (rs4648551, A>G) is associated with diminished ovarian reserve HIF-2α mediates hypoxia-induced LIF expression in human colorectal cancer cells.The tumor suppressor p53 induces expression of the pregnancy-supporting human chorionic gonadotropin (hCG) CGB7 gene.Genetic Variations in the TP53 Pathway in Native Americans Strongly Suggest Adaptation to the High Altitudes of the Andes.TP53 codon 72 Arg/Arg polymorphism is associated with a higher risk for inflammatory bowel disease development.TAp73 transcriptionally represses BNIP3 expression.Influence of TP53 Codon 72 Polymorphism Alone or in Combination with HDM2 SNP309 on Human Infertility and IVF Outcome.Tumor suppression by p53 without apoptosis and senescence: conundrum or rapalog-like gerosuppression?TP53 PIN3 and PEX4 polymorphisms and infertility associated with endometriosis or with post-in vitro fertilization implantation failure.The TP53 fertility network.The P72R Polymorphism of p53 Predisposes to Obesity and Metabolic Dysfunction.The p53 Codon 72 Polymorphism Modifies the Cellular Response to Inflammatory Challenge in the Liver

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P2860

Single-nucleotide polymorphisms in the p53 pathway regulate fertility in humans

http://www.wikidata.org/entity/Q24658392

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2009 nî lūn-bûn

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2009 թուականի Յունիսին հրատարակուած գիտական յօդուած

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2009 թվականի հունիսին հրատարակված գիտական հոդված

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2009年の論文

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2009年学术文章

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2009年学术文章

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2009年学术文章

@zh-hans

2009年学术文章

@zh-my

2009年学术文章

@zh-sg

2009年學術文章

@yue

name

Single-nucleotide polymorphisms in the p53 pathway regulate fertility in humans

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Single-nucleotide polymorphisms in the p53 pathway regulate fertility in humans

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Single-nucleotide polymorphisms in the p53 pathway regulate fertility in humans

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type

label

Single-nucleotide polymorphisms in the p53 pathway regulate fertility in humans

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Single-nucleotide polymorphisms in the p53 pathway regulate fertility in humans

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Single-nucleotide polymorphisms in the p53 pathway regulate fertility in humans

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prefLabel

Single-nucleotide polymorphisms in the p53 pathway regulate fertility in humans

@ast

Single-nucleotide polymorphisms in the p53 pathway regulate fertility in humans

@en

Single-nucleotide polymorphisms in the p53 pathway regulate fertility in humans

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PNAS.0904280106

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Proceedings of the National Academy of Sciences of the United States of America

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Single-nucleotide polymorphisms in the p53 pathway regulate fertility in humans

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Gurinder Atwal

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Hey-Joo Kang

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Timothy R Rebbeck

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Yvonne Sun

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Zhaohui Feng

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P2860

p53 regulates maternal reproduction through LIF

p63 protects the female germ line during meiotic arrest

Molecular epidemiology of human cancer risk: gene-environment interactions and p53 mutation spectrum in human lung cancer.

iASPP preferentially binds p53 proline-rich region and modulates apoptotic function of codon 72-polymorphic p53.

Haplotype structure and selection of the MDM2 oncogene in humans.

Variation in the human TP53 gene affects old age survival and cancer mortality.

The P53 pathway: what questions remain to be explored?

TAp73 knockout shows genomic instability with infertility and tumor suppressor functions.

Altered tumor formation and evolutionary selection of genetic variants in the human MDM4 oncogene.

A single nucleotide polymorphism in the MDM2 promoter attenuates the p53 tumor suppressor pathway and accelerates tumor formation in humans.

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scholarly article

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4440878

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10.1073/PNAS.0904280106

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24

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106

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Arnold J. Levine

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2009-05-22T00:00:00Z

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26241932

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19470478

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single-nucleotide polymorphism

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