Targeted ablation of NrCAM or ankyrin-B results in disorganized lens fibers leading to cataract formation
about
Crystal structure of a 12 ANK repeat stack from human ankyrinR.[Beta]IV-spectrin regulates sodium channel clustering through ankyrin-G at axon initial segments and nodes of RanvierNr-CAM is a target gene of the beta-catenin/LEF-1 pathway in melanoma and colon cancer and its expression enhances motility and confers tumorigenesisDefects in myelination, paranode organization and Purkinje cell innervation in the ether lipid-deficient mouse cerebellumTmod1 and CP49 synergize to control the fiber cell geometry, transparency, and mechanical stiffness of the mouse lensConcurrent Lpin1 and Nrcam mouse mutations result in severe peripheral neuropathy with transitory hindlimb paralysis.Switching of α-Catenin From Epithelial to Neuronal Type During Lens Epithelial Cell Differentiation.Cat-Map: putting cataract on the mapL-type calcium channels play a critical role in maintaining lens transparency by regulating phosphorylation of aquaporin-0 and myosin light chain and expression of connexinsNeuron glia-related cell adhesion molecule (NrCAM) promotes topographic retinocollicular mappingPeriaxin is required for hexagonal geometry and membrane organization of mature lens fibersMolecular characterization of mouse lens epithelial cell lines and their suitability to study RNA granules and cataract associated genesTropomodulin 1 constrains fiber cell geometry during elongation and maturation in the lens cortex"CRASH"ing with the worm: insights into L1CAM functions and mechanisms.Overlapping functions of the cell adhesion molecules Nr-CAM and L1 in cerebellar granule cell developmentAnkyrin-B directs membrane tethering of periaxin and is required for maintenance of lens fiber cell hexagonal shape and mechanics.Axonin-1/TAG-1 is required for pathfinding of granule cell axons in the developing cerebellumThe role of the lens actin cytoskeleton in fiber cell elongation and differentiation.Ankyrin-B in lens architecture and biomechanics: Just not tethering but moreTropomodulin1 is required for membrane skeleton organization and hexagonal geometry of fiber cells in the mouse lens.The membrane proteome of the mouse lens fiber cell.Functions of the intermediate filament cytoskeleton in the eye lens.Biological glass: structural determinants of eye lens transparencyThe lens actin filament cytoskeleton: Diverse structures for complex functions.Protective effects of Cassia tora leaves in experimental cataract by modulating intracellular communication, membrane co-transporters, energy metabolism and the ubiquitin-proteasome pathway.Calpain expression and activity during lens fiber cell differentiation.N-cadherin is essential for retinal lamination in the zebrafish.Overexpression of neurone glial-related cell adhesion molecule is an independent predictor of poor prognosis in advanced colorectal cancer.
P2860
Q24539221-D7D0A9B7-0340-4A44-BD7B-7669687AA356Q24652657-2104C52E-2F52-4B6D-BC8A-B2CE3F2E7149Q24673777-BC89CA32-8584-4FDE-86D8-0ACEADF8AC65Q28512474-C3BBCE9D-B7AE-4362-90AA-C6359D3F1DDCQ28594029-7F4441AC-D621-4A54-9A59-3EFB4B9E1E52Q30491463-A9A597B7-DB21-4B33-AA39-1C434D0007FCQ33893550-864C5494-8401-4D32-BBA2-054E99DD4D9DQ34248597-EABDA5FE-3B90-4DCE-84FC-831D6F88DB3DQ34755622-4CA55A27-521B-49F3-955A-AE0CF1D724FFQ34984178-84FBA638-018E-49D7-94A5-6B0375225338Q35189801-B5E030FB-E529-4797-B4D3-3A51163C89A0Q35288086-60496EA4-869E-4A8E-9A4D-13EF9A12815BQ36085636-FA9AA43E-000F-45EB-AE96-62E7110A6EBEQ36190593-D6527819-9CA8-4770-AAC0-0B1262A06905Q36294022-94DA8348-D460-4909-A76F-52AD86141CFFQ36480318-E1007F85-3C11-48EA-A9DD-1253DEB0E0ECQ36569955-8C22DDEB-D04B-4F88-8AE3-68ADB9903ACBQ36673199-940633F5-9F4C-4886-BF89-05714D598110Q37021371-489C0001-8FA0-478A-8A58-74D3602107D3Q37365423-25FD391A-E82D-459B-901A-5F2A958CEBFCQ37452611-7237D7FB-B58D-4183-AB25-BFF64087015BQ37545190-FF8AA0ED-4113-467C-918F-1C7C0C9F142BQ37852898-F1F27D3B-9A61-4322-A284-44517816AE58Q38772098-B70BA626-F7FC-4434-844A-BB6A6FCDF899Q38920311-8205BD79-949C-4148-815D-5138645F5382Q43131501-A34FE742-AB8C-42FF-88B3-202B00FBBA98Q44347486-A7321BE9-B5A9-4287-954B-828A838853C3Q44768409-B968C8BE-743C-40A5-A103-25C0CE249AD4
P2860
Targeted ablation of NrCAM or ankyrin-B results in disorganized lens fibers leading to cataract formation
description
2001 nî lūn-bûn
@nan
2001 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Targeted ablation of NrCAM or ...... leading to cataract formation
@ast
Targeted ablation of NrCAM or ...... leading to cataract formation
@en
Targeted ablation of NrCAM or ...... leading to cataract formation
@nl
type
label
Targeted ablation of NrCAM or ...... leading to cataract formation
@ast
Targeted ablation of NrCAM or ...... leading to cataract formation
@en
Targeted ablation of NrCAM or ...... leading to cataract formation
@nl
prefLabel
Targeted ablation of NrCAM or ...... leading to cataract formation
@ast
Targeted ablation of NrCAM or ...... leading to cataract formation
@en
Targeted ablation of NrCAM or ...... leading to cataract formation
@nl
P2093
P2860
P356
P1476
Targeted ablation of NrCAM or ...... leading to cataract formation
@en
P2093
P2860
P304
P356
10.1083/JCB.200104038
P407
P577
2001-07-09T00:00:00Z