CD6 regulates T-cell responses through activation-dependent recruitment of the positive regulator SLP-76 - Wikidata - awgldk - TriplyDB

CD6 regulates T-cell responses through activation-dependent recruitment of the positive regulator SLP-76

CD6 regulates T-cell responses through activation-dependent recruitment of the positive regulator SLP-76

http://www.wikidata.org/entity/Q24670421

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Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci Cell Adhesion Molecules and Ubiquitination-Functions and Significance Genomic Variants Revealed by Invariably Missing Genotypes in Nelore Cattle A polymorphism in a phosphotyrosine signalling motif of CD229 (Ly9, SLAMF3) alters SH2 domain binding and T-cell activation Fine specificity and molecular competition in SLAM family receptor signalling A ligand for CD5 is CD5 An investigation of hierachical protein recruitment to the inhibitory platelet receptor, G6B-b Quantitative proteomics analysis of signalosome dynamics in primary T cells identifies the surface receptor CD6 as a Lat adaptor-independent TCR signaling hub Completion of proteomic data sets by Kd measurement using cell-free synthesis of site-specifically labeled proteins.Cell Adhesion Molecule CD166/ALCAM Functions Within the Crypt to Orchestrate Murine Intestinal Stem Cell Homeostasis.T Cell Costimulation by CD6 Is Dependent on Bivalent Binding of a GADS/SLP-76 Complex.Human CD6 Down-Modulation following T-Cell Activation Compromises Lymphocyte Survival and Proliferative Responses.T cell activation and differentiation is modulated by a CD6 domain 1 antibody Itolizumab Multiple sclerosis susceptibility alleles in African Americans.CD6 as a therapeutic target in autoimmune diseases: successes and challenges.GADS is required for TCR-mediated calcium influx and cytokine release, but not cellular adhesion, in human T cells ALCAM: Basis Sequence: Mouse CD6 attenuates early and late signaling events, setting thresholds for T-cell activation Genetic basis of autoimmunity.Structures of CD6 and Its Ligand CD166 Give Insight into Their Interaction.Naïve helper T cells with high CD5 expression have increased calcium signaling.Glycerol Monolaurate (GML) inhibits human T cell signaling and function by disrupting lipid dynamics.CD6 modulates thymocyte selection and peripheral T cell homeostasis Genome-wide analysis of allelic expression imbalance in human primary cells by high-throughput transcriptome resequencing.Coordination of receptor signaling in multiple hematopoietic cell lineages by the adaptor protein SLP-76 Risk conferring genes in multiple sclerosis.CD6 synergistic co-stimulation promoting proinflammatory response is modulated without interfering with the activated leucocyte cell adhesion molecule interaction.Relevance of CD6-Mediated Interactions in the Regulation of Peripheral T-Cell Responses and Tolerance.Rationale for Targeting CD6 as a Treatment for Autoimmune Diseases.The SLP-76 Src homology 2 domain is required for T cell development and activation.Essential roles for Dok2 and RasGAP in CD200 receptor-mediated regulation of human myeloid cells Inhibition and activation by CD244 depends on CD2 and phospholipase C-gamma1 Synovial fibroblasts in 2017.Prognostic Significance of Activated Leukocyte Cell Adhesion Molecule (ALCAM) in Association with Promoter Methylation of the ALCAM Gene in Breast Cancer.Dual Face of Vγ9Vδ2-T Cells in Tumor Immunology: Anti- versus Pro-Tumoral Activities.Identification of functionally relevant phoshorylatable serine clusters in the cytoplasmic region of the human CD6 lymphocyte surface receptor.CD6 and Linker of Activated T Cells are Potential Interaction Partners for T Cell-Specific Adaptor Protein.T Cell Calcium Signaling Regulation by the Co-Receptor CD5.Biophysical Characterization of CD6-TCR/CD3 Interplay in T Cells

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P2860

CD6 regulates T-cell responses through activation-dependent recruitment of the positive regulator SLP-76

http://www.wikidata.org/entity/Q24670421

description

2006 nî lūn-bûn

@nan

2006 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2006 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2006年の論文

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2006年論文

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2006年論文

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2006年論文

@zh-hk

2006年論文

@zh-mo

2006年論文

@zh-tw

2006年论文

@wuu

name

CD6 regulates T-cell responses ...... the positive regulator SLP-76

@ast

CD6 regulates T-cell responses ...... the positive regulator SLP-76

@en

CD6 regulates T-cell responses ...... the positive regulator SLP-76

@nl

type

label

CD6 regulates T-cell responses ...... the positive regulator SLP-76

@ast

CD6 regulates T-cell responses ...... the positive regulator SLP-76

@en

CD6 regulates T-cell responses ...... the positive regulator SLP-76

@nl

prefLabel

CD6 regulates T-cell responses ...... the positive regulator SLP-76

@ast

CD6 regulates T-cell responses ...... the positive regulator SLP-76

@en

CD6 regulates T-cell responses ...... the positive regulator SLP-76

@nl

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Molecular and Cellular Biology

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CD6 regulates T-cell responses ...... the positive regulator SLP-76

@en

P2093

A Neil Barclay

http://www.w3.org/2001/XMLSchema#string

Marion H Brown

http://www.w3.org/2001/XMLSchema#string

Martine Bomb

http://www.w3.org/2001/XMLSchema#string

Michael J Puklavec

http://www.w3.org/2001/XMLSchema#string

Namir J Hassan

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Nicholas G Clarkson

http://www.w3.org/2001/XMLSchema#string

Sarah Hanrahan

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Stephen J Simmonds

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P2860

Crystal structures of the XLP protein SAP reveal a class of SH2 domains with extended, phosphotyrosine-independent sequence recognition

Long-term engagement of CD6 and ALCAM is essential for T-cell proliferation induced by dendritic cells

Relevance of CD6-mediated interactions in T cell activation and proliferation

Measurement of the binding of tyrosyl phosphopeptides to SH2 domains: a reappraisal

Cloning of a novel T-cell protein FYB that binds FYN and SH2-domain-containing leukocyte protein 76 and modulates interleukin 2 production

Cloning, mapping, and characterization of activated leukocyte-cell adhesion molecule (ALCAM), a CD6 ligand

2B4, the natural killer and T cell immunoglobulin superfamily surface protein, is a ligand for CD48

Tyrosine phosphorylation of CD6 by stimulation of CD3: augmentation by the CD4 and CD2 coreceptors

Structural basis for SH3 domain-mediated high-affinity binding between Mona/Gads and SLP-76

The structure of the membrane distal phosphatase domain of RPTPalpha reveals interdomain flexibility and an SH2 domain interaction region

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6727-38

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scholarly article

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4405724

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10.1128/MCB.00688-06

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17

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26

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2006-09-01T00:00:00Z

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16914752

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1592849

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