Identification of IGF2 signaling through phosphoinositide-3-kinase regulatory subunit 3 as a growth-promoting axis in glioblastoma
about
Targeting the insulin growth factor receptor 1Aberrant expression of interleukin-1β and inflammasome activation in human malignant gliomasCentral Neurocytoma: A Review of Clinical Management and Histopathologic FeaturesInsulin-mediated signaling promotes proliferation and survival of glioblastoma through Akt activationTMEFF2 is a PDGF-AA binding protein with methylation-associated gene silencing in multiple cancer types including gliomaIGF-IR: a new prognostic biomarker for human glioblastomaTranscriptional targeting of glioblastoma by diphtheria toxin-A driven by both H19 and IGF2-P4 promoters.Heterozygosity for Pten promotes tumorigenesis in a mouse model of medulloblastoma.CRISPR Cas9-guided chromatin immunoprecipitation identifies miR483 as an epigenetic modulator of IGF2 imprinting in tumors.ESR1 mutations affect anti-proliferative responses to tamoxifen through enhanced cross-talk with IGF signalingThe cerebrospinal fluid provides a proliferative niche for neural progenitor cells.MicroRNA-7-regulated TLR9 signaling-enhanced growth and metastatic potential of human lung cancer cells by altering the phosphoinositide-3-kinase, regulatory subunit 3/Akt pathwayGenetic and bioinformatic analyses of the expression and function of PI3K regulatory subunit PIK3R3 in an Asian patient gastric cancer libraryFrom QTL to QTN: candidate gene set approach and a case study in porcine IGF1-FoxO pathway.Anti-tumor effect of a novel PI3-kinase inhibitor, SF1126, in (12) V-Ha-Ras transgenic mouse glioma model.Frequent genetic abnormalities of the PI3K/AKT pathway in primary ovarian cancer predict patient outcomeEnhanced efficacy of IGF1R inhibition in pediatric glioblastoma by combinatorial targeting of PDGFRα/β.AKT hyper-phosphorylation associated with PI3K mutations in lymphatic endothelial cells from a patient with lymphatic malformation.Human cytomegalovirus gene expression in long-term infected glioma stem cells.Variable expression of PIK3R3 and PTEN in Ewing Sarcoma impacts oncogenic phenotypes.Phase I trial of vorinostat combined with bevacizumab and CPT-11 in recurrent glioblastoma.Inhibition of intracerebral glioblastoma growth by targeting the insulin-like growth factor 1 receptor involves different context-dependent mechanisms.An integer linear programming approach for finding deregulated subgraphs in regulatory networks.Emerging insights into the molecular and cellular basis of glioblastoma.Igf2 ligand dependency of Pten(+/-) developmental and tumour phenotypes in the mouseAnalysis of whole genomic expression profiles and screening of the key signaling pathways associated with pancreatic cancerImp2 regulates GBM progression by activating IGF2/PI3K/Akt pathway.Histologically defined intratumoral sequencing uncovers evolutionary cues into conserved molecular events driving gliomagenesis.Truncating PREX2 mutations activate its GEF activity and alter gene expression regulation in NRAS-mutant melanomaInsR/IGF1R Pathway Mediates Resistance to EGFR Inhibitors in Glioblastoma.Integrative analysis reveals the direct and indirect interactions between DNA copy number aberrations and gene expression changes.Neurogenesis at the brain-cerebrospinal fluid interface.Cidofovir: a novel antitumor agent for glioblastoma.Loss of insulin-like growth factor II imprinting is a hallmark associated with enhanced chemo/radiotherapy resistance in cancer stem cells.Molecular subclassification of diffuse gliomas: seeing order in the chaos.Lessons from a decade of integrating cancer copy number alterations with gene expression profiles.Genomic profiling of glioblastoma: convergence of fundamental biologic tenets and novel insights.Biology and significance of signalling pathways activated by IGF-II.Chromosomal Instability and Phosphoinositide Pathway Gene Signatures in Glioblastoma MultiformeRegulation of IGF2 transcript and protein expression by altered methylation in breast cancer.
P2860
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P2860
Identification of IGF2 signaling through phosphoinositide-3-kinase regulatory subunit 3 as a growth-promoting axis in glioblastoma
description
2007 nî lūn-bûn
@nan
2007 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Identification of IGF2 signali ...... promoting axis in glioblastoma
@ast
Identification of IGF2 signali ...... promoting axis in glioblastoma
@en
Identification of IGF2 signali ...... promoting axis in glioblastoma
@nl
type
label
Identification of IGF2 signali ...... promoting axis in glioblastoma
@ast
Identification of IGF2 signali ...... promoting axis in glioblastoma
@en
Identification of IGF2 signali ...... promoting axis in glioblastoma
@nl
prefLabel
Identification of IGF2 signali ...... promoting axis in glioblastoma
@ast
Identification of IGF2 signali ...... promoting axis in glioblastoma
@en
Identification of IGF2 signali ...... promoting axis in glioblastoma
@nl
P2093
P2860
P3181
P356
P1476
Identification of IGF2 signali ...... promoting axis in glioblastoma
@en
P2093
Anjan Misra
Burt G Feuerstein
Heidi S Phillips
Janice M Nigro
Jiping Zha
Ken Aldape
Liliana Soroceanu
Robert H Soriano
Ruihuan Chen
Samir Kharbanda
P2860
P304
P3181
P356
10.1073/PNAS.0611271104
P407
P577
2007-02-27T00:00:00Z