The KAP1 corepressor functions to coordinate the assembly of de novo HP1-demarcated microenvironments of heterochromatin required for KRAB zinc finger protein-mediated transcriptional repression - Wikidata - awgldk - TriplyDB

The KAP1 corepressor functions to coordinate the assembly of de novo HP1-demarcated microenvironments of heterochromatin required for KRAB zinc finger protein-mediated transcriptional repression

The KAP1 corepressor functions to coordinate the assembly of de novo HP1-demarcated microenvironments of heterochromatin required for KRAB zinc finger protein-mediated transcriptional repression

http://www.wikidata.org/entity/Q24672128

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Genome-wide analysis of KAP1 binding suggests autoregulation of KRAB-ZNFs PHD domain-mediated E3 ligase activity directs intramolecular sumoylation of an adjacent bromodomain required for gene silencing SUMOylation of the transcriptional co-repressor KAP1 is regulated by the serine and threonine phosphatase PP1 ZNF274 recruits the histone methyltransferase SETDB1 to the 3' ends of ZNF genes Human BAHD1 promotes heterochromatic gene silencing.Regulation of E2F1 function by the nuclear corepressor KAP1 Novel activity of KRAB domain that functions to reinforce nuclear localization of KRAB-containing zinc finger proteins by interacting with KAP1 Coevolution of retroelements and tandem zinc finger genes Transposable elements in the mammalian embryo: pioneers surviving through stealth and service Transposable elements at the center of the crossroads between embryogenesis, embryonic stem cells, reprogramming, and long non-coding RNAs TRIM28 as a novel transcriptional elongation factor Progress and Prospects of Anti-HBV Gene Therapy Development KAPtain in charge of multiple missions: Emerging roles of KAP1 Retroviral transcriptional regulation and embryonic stem cells: war and peace KAP1 regulates gene networks controlling T-cell development and responsiveness.The epigenome: the next substrate for engineering KRAB-zinc finger proteins and KAP1 can mediate long-range transcriptional repression through heterochromatin spreading A role for CARM1-mediated histone H3 arginine methylation in protecting histone acetylation by releasing corepressors from chromatin The KRAB zinc finger protein RSL1 regulates sex- and tissue-specific promoter methylation and dynamic hormone-responsive chromatin configuration Epigenetic gene silencing by the SRY protein is mediated by a KRAB-O protein that recruits the KAP1 co-repressor machinery TRIM28 is required by the mouse KRAB domain protein ZFP568 to control convergent extension and morphogenesis of extra-embryonic tissues A unique SUMO-2-interacting motif within LANA is essential for KSHV latency Distinct roles of KAP1, HP1 and G9a/GLP in silencing of the two-cell-specific retrotransposon MERVL in mouse ES cells Discovery and characterization of chromatin states for systematic annotation of the human genome Genome-wide search identifies Ccnd2 as a direct transcriptional target of Elf5 in mouse mammary gland.Genomic targets of the KRAB and SCAN domain-containing zinc finger protein 263 Drosophila SETDB1 is required for chromosome 4 silencing dSETDB1 and SU(VAR)3-9 sequentially function during germline-stem cell differentiation in Drosophila melanogaster.Phosphorylation at Ser473 regulates heterochromatin protein 1 binding and corepressor function of TIF1beta/KAP1.Adaptive evolution in zinc finger transcription factors.NCoR1 mediates papillomavirus E8;E2C transcriptional repression Characterization of the contradictory chromatin signatures at the 3' exons of zinc finger genes.HP1-mediated formation of alternative lengthening of telomeres-associated PML bodies requires HIRA but not ASF1a.Identification of DIM-7, a protein required to target the DIM-5 H3 methyltransferase to chromatin.TIF1beta regulates the pluripotency of embryonic stem cells in a phosphorylation-dependent manner.A gene-rich, transcriptionally active environment and the pre-deposition of repressive marks are predictive of susceptibility to KRAB/KAP1-mediated silencing.Isoform-specific intermolecular disulfide bond formation of heterochromatin protein 1 (HP1)Transcription cofactors TRIM24, TRIM28, and TRIM33 associate to form regulatory complexes that suppress murine hepatocellular carcinoma Epigenetic modification of TLRs in leukocytes is associated with increased susceptibility to Salmonella enteritidis in chickens Analysis of an artificial zinc finger epigenetic modulator: widespread binding but limited regulation.

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The KAP1 corepressor functions to coordinate the assembly of de novo HP1-demarcated microenvironments of heterochromatin required for KRAB zinc finger protein-mediated transcriptional repression

http://www.wikidata.org/entity/Q24672128

description

2006 nî lūn-bûn

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2006 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2006 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2006年の論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年论文

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name

The KAP1 corepressor functions ...... ted transcriptional repression

@ast

The KAP1 corepressor functions ...... ted transcriptional repression

@en

The KAP1 corepressor functions ...... ted transcriptional repression

@nl

type

label

The KAP1 corepressor functions ...... ted transcriptional repression

@ast

The KAP1 corepressor functions ...... ted transcriptional repression

@en

The KAP1 corepressor functions ...... ted transcriptional repression

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prefLabel

The KAP1 corepressor functions ...... ted transcriptional repression

@ast

The KAP1 corepressor functions ...... ted transcriptional repression

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The KAP1 corepressor functions ...... ted transcriptional repression

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Molecular and Cellular Biology

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The KAP1 corepressor functions ...... ted transcriptional repression

@en

P2093

David C Schultz

http://www.w3.org/2001/XMLSchema#string

Jessica Stevens

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Smitha P Sripathy

http://www.w3.org/2001/XMLSchema#string

P2860

Initial sequencing and analysis of the human genome

TIF1gamma, a novel member of the transcriptional intermediary factor 1 family

Structure and ligand of a histone acetyltransferase bromodomain

KAP-1 corepressor protein interacts and colocalizes with heterochromatic and euchromatic HP1 proteins: a potential role for Krüppel-associated box-zinc finger proteins in heterochromatin-mediated gene silencing.

Reconstitution of the KRAB-KAP-1 repressor complex: a model system for defining the molecular anatomy of RING-B box-coiled-coil domain-mediated protein-protein interactions

Translating the Histone Code

Solution structure of the PHD domain from the KAP-1 corepressor: structural determinants for PHD, RING and LIM zinc-binding domains.

The mammalian heterochromatin protein 1 binds diverse nuclear proteins through a common motif that targets the chromoshadow domain

Transcriptional repression by RING finger protein TIF1 beta that interacts with the KRAB repressor domain of KOX1

KAP-1, a novel corepressor for the highly conserved KRAB repression domain

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8623-38

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scholarly article

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1778746

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10.1128/MCB.00487-06

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22

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26

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2006-11-01T00:00:00Z

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16954381

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1636786

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