P2Y-like receptor, GPR105 (P2Y14), identifies and mediates chemotaxis of bone-marrow hematopoietic stem cells - Wikidata - awgldk - TriplyDB

P2Y-like receptor, GPR105 (P2Y14), identifies and mediates chemotaxis of bone-marrow hematopoietic stem cells

P2Y-like receptor, GPR105 (P2Y14), identifies and mediates chemotaxis of bone-marrow hematopoietic stem cells

http://www.wikidata.org/entity/Q24672262

about

International Union of Pharmacology LVIII: update on the P2Y G protein-coupled nucleotide receptors: from molecular mechanisms and pathophysiology to therapy Expression analysis of G Protein-Coupled Receptors in mouse macrophages UDP-glucose acting at P2Y14 receptors is a mediator of mast cell degranulation Purinergic P2Y₁₄ receptor modulates stress-induced hematopoietic stem/progenitor cell senescence Signalling and pharmacological properties of the P2Y receptor.The G protein-coupled receptor P2Y14 influences insulin release and smooth muscle function in mice.The properties of a mammary gland cancer stem cell Transcriptome analysis of genes regulated by cholesterol loading in two strains of mouse macrophages associates lysosome pathway and ER stress response with atherosclerosis susceptibility Hematopoietic stem cells proliferate until after birth and show a reversible phase-specific engraftment defect.UDP-Sugars as Extracellular Signaling Molecules: Cellular and Physiologic Consequences of P2Y14 Receptor Activation.Regulation of hematopoietic stem cell growth.Structure-activity relationship of uridine 5'-diphosphoglucose analogues as agonists of the human P2Y14 receptor GPR105 ablation prevents inflammation and improves insulin sensitivity in mice with diet-induced obesity From quiescence to senescence.Activation of human eosinophils via P2 receptors: novel findings and future perspectives.The UDP-sugar-sensing P2Y(14) receptor promotes Rho-mediated signaling and chemotaxis in human neutrophils.A selective high-affinity antagonist of the P2Y14 receptor inhibits UDP-glucose-stimulated chemotaxis of human neutrophils.Toward 'SMART' stem cells.The nucleotide sugar UDP-glucose mobilizes long-term repopulating primitive hematopoietic cells.The purinergic P2Y14 receptor axis is a molecular determinant for organism survival under in utero radiation toxicity Chemotactic activity of extracellular nucleotideson human immune cells.Endoplasmic reticulum/golgi nucleotide sugar transporters contribute to the cellular release of UDP-sugar signaling molecules UDP-glucose promotes neutrophil recruitment in the lung.Selective induction of P2Y14 receptor by RANKL promotes osteoclast formation.Quantification of extracellular UDP-galactose.Perspectives of purinergic signaling in stem cell differentiation and tissue regeneration.Thrombin-promoted release of UDP-glucose from human astrocytoma cells.Gi-dependent cell signaling responses of the human P2Y14 receptor in model cell systems Wnt3A activates canonical Wnt signalling in acute lymphoblastic leukaemia (ALL) cells and inhibits the proliferation of B-ALL cell lines.Identification of a molecular signature predictive of sensitivity to differentiation induction in acute myeloid leukemia.Shaping immune responses through the activation of dendritic cells' P2 receptors.Regulation of innate immunity by extracellular nucleotides The P2Y14 receptor of airway epithelial cells: coupling to intracellular Ca2+ and IL-8 secretion.Identification of the nonreceptor tyrosine kinase MATK/CHK as an essential regulator of immune cells using Matk/CHK-deficient mice.Extracellular UDP-glucose activates P2Y14 Receptor and Induces Signal Transducer and Activator of Transcription 3 (STAT3) Tyr705 phosphorylation and binding to hyaluronan synthase 2 (HAS2) promoter, stimulating hyaluronan synthesis of keratinocytes.Differential regulation of immune responses and macrophage/neuron interactions in the dorsal root ganglion in young and adult rats following nerve injury.Multiple P2Y subtypes in spinal microglia are involved in neuropathic pain after peripheral nerve injury.P2Y14 receptor activation decreases interleukin-6 production and glioma GL261 cell proliferation in microglial transwell cultures.P2Y2 Nucleotide Receptor Prompts Human Cardiac Progenitor Cell Activation by Modulating Hippo Signaling.The expression of P2Y14, a purinergic G-protein coupled receptor, defines functionally distinct subpopulations in placenta-derived hematopoietic stem progenitor cells.

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P2860

P2Y-like receptor, GPR105 (P2Y14), identifies and mediates chemotaxis of bone-marrow hematopoietic stem cells

http://www.wikidata.org/entity/Q24672262

description

2003 nî lūn-bûn

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2003 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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2003 թվականի հուլիսին հրատարակված գիտական հոդված

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2003年の論文

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2003年論文

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2003年論文

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2003年論文

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2003年论文

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name

P2Y-like receptor, GPR105 (P2Y ...... arrow hematopoietic stem cells

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P2Y-like receptor, GPR105 (P2Y ...... arrow hematopoietic stem cells

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P2Y-like receptor, GPR105 (P2Y ...... arrow hematopoietic stem cells

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type

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P2Y-like receptor, GPR105 (P2Y ...... arrow hematopoietic stem cells

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P2Y-like receptor, GPR105 (P2Y ...... arrow hematopoietic stem cells

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P2Y-like receptor, GPR105 (P2Y ...... arrow hematopoietic stem cells

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P2Y-like receptor, GPR105 (P2Y ...... arrow hematopoietic stem cells

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P2Y-like receptor, GPR105 (P2Y ...... arrow hematopoietic stem cells

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P2Y-like receptor, GPR105 (P2Y ...... arrow hematopoietic stem cells

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Genes & Development

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P2Y-like receptor, GPR105 (P2Y ...... arrow hematopoietic stem cells

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P2093

Andrew D Luster

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Byeong-Chel Lee

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Daniel A Haber

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David Dombkowski

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David T Scadden

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Douglas P Olson

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Eyal C Attar

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Gregor B Adams

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Ivona Olszak

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Julie Hancock

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P2860

Chemokine receptor expression and signaling in macaque and human fetal neurons and astrocytes: implications for the neuropathogenesis of AIDS

A G protein-coupled receptor for UDP-glucose

Molecular cloning of TER1, a chemokine receptor-like gene expressed by lymphoid tissues

Multi-organ, multi-lineage engraftment by a single bone marrow-derived stem cell

Characterization of the UDP-glucose receptor (re-named here the P2Y14 receptor) adds diversity to the P2Y receptor family

The isolation and characterization of a novel G protein-coupled receptor regulated by immunologic challenge

Prediction of the coding sequences of unidentified human genes. I. The coding sequences of 40 new genes (KIAA0001-KIAA0040) deduced by analysis of randomly sampled cDNA clones from human immature myeloid cell line KG-1

Nucleotide receptors: an emerging family of regulatory molecules in blood cells

"Stemness": transcriptional profiling of embryonic and adult stem cells

The genetic program of hematopoietic stem cells.

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1592-604

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10.1101/GAD.1071503

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13

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17

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10676646

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12842911

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196132

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