The crystal structure of Lactococcus lactis dihydroorotate dehydrogenase A complexed with the enzyme reaction product throws light on its enzymatic function
about
Crystal structure of dihydropyrimidine dehydrogenase, a major determinant of the pharmacokinetics of the anti-cancer drug 5-fluorouracilCrystal structure of the productive ternary complex of dihydropyrimidine dehydrogenase with NADPH and 5-iodouracil. Implications for mechanism of inhibition and electron transferLactococcus lactis dihydroorotate dehydrogenase A mutants reveal important facets of the enzymatic functionMolecular basis of dihydrouridine formation on tRNAEukaryotic beta-alanine synthases are functionally related but have a high degree of structural diversityInhibitor binding in a class 2 dihydroorotate dehydrogenase causes variations in the membrane-associated N-terminal domainIdentification of a cysteine residue in the active site of nitroalkane oxidase by modification with N-ethylmaleimide.Purification and properties of hydroquinone hydroxylase, a FAD-dependent monooxygenase involved in the catabolism of 4-hydroxybenzoate in Candida parapsilosis CBS604.Catabolite control protein A (CcpA) contributes to virulence and regulation of sugar metabolism in Streptococcus pneumoniae.Molecular evolution of dihydrouridine synthases.Single-molecule kinetics reveals signatures of half-sites reactivity in dihydroorotate dehydrogenase A catalysisNucleotide metabolism and its control in lactic acid bacteria.New functional families (FunFams) in CATH to improve the mapping of conserved functional sites to 3D structures.The dimeric dihydroorotate dehydrogenase A from Lactococcus lactis dissociates reversibly into inactive monomers.Molecular mimicry of substrate oxygen atoms by water molecules in the beta-amylase active site.Insights into the mechanism of oxidation of dihydroorotate to orotate catalysed by human class 2 dihydroorotate dehydrogenase: a QM/MM free energy study.Expression, purification and crystallization of Trypanosoma cruzi dihydroorotate dehydrogenase complexed with orotateCrystallization and preliminary X-ray diffraction analysis of Leishmania major dihydroorotate dehydrogenase.Defects in vesicle core induced by escherichia coli dihydroorotate dehydrogenase.Contribution of flavin covalent linkage with histidine 99 to the reaction catalyzed by choline oxidase.Disruption of the proton relay network in the class 2 dihydroorotate dehydrogenase from Escherichia coli.Roles in binding and chemistry for conserved active site residues in the class 2 dihydroorotate dehydrogenase from Escherichia coli.Computational study of the mechanism of half-reactions in class 1A dihydroorotate dehydrogenase from Trypanosoma cruzi.On the iron-sulfur clusters in the complex redox enzyme dihydropyrimidine dehydrogenase
P2860
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P2860
The crystal structure of Lactococcus lactis dihydroorotate dehydrogenase A complexed with the enzyme reaction product throws light on its enzymatic function
description
1998 nî lūn-bûn
@nan
1998 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
The crystal structure of Lacto ...... ight on its enzymatic function
@ast
The crystal structure of Lacto ...... ight on its enzymatic function
@en
The crystal structure of Lacto ...... ight on its enzymatic function
@nl
type
label
The crystal structure of Lacto ...... ight on its enzymatic function
@ast
The crystal structure of Lacto ...... ight on its enzymatic function
@en
The crystal structure of Lacto ...... ight on its enzymatic function
@nl
altLabel
The crystal structure oflactoc ...... ight on its enzymatic function
@en
prefLabel
The crystal structure of Lacto ...... ight on its enzymatic function
@ast
The crystal structure of Lacto ...... ight on its enzymatic function
@en
The crystal structure of Lacto ...... ight on its enzymatic function
@nl
P2093
P2860
P356
P1433
P1476
The crystal structure of Lacto ...... ight on its enzymatic function
@en
P2093
F S Nielsen
K F Jensen
O Björnberg
P2860
P304
P356
10.1002/PRO.5560070601
P407
P577
1998-06-01T00:00:00Z