Gambogic amide, a selective agonist for TrkA receptor that possesses robust neurotrophic activity, prevents neuronal cell death
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Deoxygedunin, a natural product with potent neurotrophic activity in miceNeurosteroid dehydroepiandrosterone interacts with nerve growth factor (NGF) receptors, preventing neuronal apoptosisNovel small molecule activators of the Trk family of receptor tyrosine kinasesAmitriptyline is a TrkA and TrkB receptor agonist that promotes TrkA/TrkB heterodimerization and has potent neurotrophic activityNeuroprotection by spice-derived nutraceuticals: you are what you eat!Low molecular weight, non-peptidic agonists of TrkA receptor with NGF-mimetic activitySmall molecule activators of the Trk receptors for neuroprotectionComparison of electron capture-atmospheric pressure chemical ionization and electrospray ionization for the analysis of gambogic acid and its main circulating metabolite in dog plasma.Bivalent peptidomimetic ligands of TrkC are biased agonists and selectively induce neuritogenesis or potentiate neurotrophin-3 trophic signalsA selective TrkB agonist with potent neurotrophic activities by 7,8-dihydroxyflavone.A monovalent agonist of TrkA tyrosine kinase receptors can be converted into a bivalent antagonist.Small-molecule modulation of neurotrophin receptors: a strategy for the treatment of neurological disease.Key proteins of activating cell death can be predicted through a kainic acid-induced excitotoxic stress.Methyl jasmonate sensitizes human bladder cancer cells to gambogic acid-induced apoptosis through down-regulation of EZH2 expression by miR-101.Chemistry and biology of the caged Garcinia xanthones.The natural compound Guttiferone F sensitizes prostate cancer to starvation induced apoptosis via calcium and JNK elevationPoloxamer 407/TPGS mixed micelles for delivery of gambogic acid to breast and multidrug-resistant cancer.Recent research on bioactive xanthones from natural medicine: Garcinia hanburyi.Computational Study on the Conformations of Gambogic AcidNGF inhibits human leukemia proliferation by downregulating cyclin A1 expression through promoting acinus/CtBP2 association.Ras family small GTPase-mediated neuroprotective signaling in stroke.Understanding cytokine and growth factor receptor activation mechanisms.Target identification for CNS diseases by transcriptional profiling.Cholinergic system during the progression of Alzheimer's disease: therapeutic implications.Transcriptional dysregulation of TrkA associates with neurodegeneration in spinocerebellar ataxia type 17.Neurotrophic natural products: chemistry and biology.Prenylated caged xanthones: chemistry and biology.Gambogic Acid and Its Role in Chronic Diseases.The use of TrkA-PathHunter assay in high-throughput screening to identify compounds that affect nerve growth factor signaling.Synthesis and evaluation of gambogic acid derivatives as antitumor agents. Part III.Studies on chemical-structure modification and structure-activity relationship of gambogic acid derivatives at carbon(34).Studies on chemical structure modification and structure-activity relationship of derivatives of gambogic acid at C(39).Antitumor effects of novel compound, guttiferone K, on colon cancer by p21Waf1/Cip1-mediated G(0) /G(1) cell cycle arrest and apoptosis.Kinomic profiling approach identifies Trk as a novel radiation modulator.Inhibition of neuronal apoptosis and axonal regression ameliorates sympathetic atrophy and hemodynamic alterations in portal hypertensive rats.Functional expression of full-length TrkA in the prokaryotic host Magnetospirillum magneticum AMB-1 by using a magnetosome display system.Neuroprotection by sildenafil: neuronal networks potentiation in acute experimental stroke.Modulating Neurotrophin Receptor Signaling as a Therapeutic Strategy for Huntington's Disease.Natural product modulators of human sensations and mood: molecular mechanisms and therapeutic potential.Phosphorylation of NTRK1 at Y674/Y675 induced by TP53-dependent repression of PTPN6 expression: a potential novel prognostic marker for breast cancer.
P2860
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P2860
Gambogic amide, a selective agonist for TrkA receptor that possesses robust neurotrophic activity, prevents neuronal cell death
description
2007 nî lūn-bûn
@nan
2007 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Gambogic amide, a selective ag ...... , prevents neuronal cell death
@ast
Gambogic amide, a selective ag ...... , prevents neuronal cell death
@en
Gambogic amide, a selective ag ...... , prevents neuronal cell death
@nl
type
label
Gambogic amide, a selective ag ...... , prevents neuronal cell death
@ast
Gambogic amide, a selective ag ...... , prevents neuronal cell death
@en
Gambogic amide, a selective ag ...... , prevents neuronal cell death
@nl
prefLabel
Gambogic amide, a selective ag ...... , prevents neuronal cell death
@ast
Gambogic amide, a selective ag ...... , prevents neuronal cell death
@en
Gambogic amide, a selective ag ...... , prevents neuronal cell death
@nl
P2093
P2860
P356
P1476
Gambogic amide, a selective ag ...... , prevents neuronal cell death
@en
P2093
Donald Stein
Iqbal Sayeed
Keqiang Ye
Masashi Okada
Sung-Wuk Jang
P2860
P304
P356
10.1073/PNAS.0706662104
P407
P577
2007-10-09T00:00:00Z