Genetic targeting of the kinase activity of the Met receptor in cancer cells
about
Replacement of normal with mutant alleles in the genome of normal human cells unveils mutation-specific drug responsesMet in urological cancersDrug development against metastasis-related genes and their pathways: A rationale for cancer therapyThe Concise Guide to PHARMACOLOGY 2013/14: catalytic receptors.Significance of c-MET overexpression in cytotoxic anticancer drug-resistant small-cell lung cancer cellsThe c-MET Network as Novel Prognostic Marker for Predicting Bladder Cancer Patients with an Increased Risk of Developing Aggressive Disease.The hepatocyte growth factor receptor as a potential therapeutic target for dedifferentiated liposarcomaHepatocyte-specific c-Met deletion disrupts redox homeostasis and sensitizes to Fas-mediated apoptosis.Screening of liver-targeted drugs.Tivantinib (ARQ 197) affects the apoptotic and proliferative machinery downstream of c-MET: role of Mcl-1, Bcl-xl and Cyclin B1.Knockdown of c-MET induced apoptosis in ABCB1-overexpressed multidrug-resistance cancer cell lines.Targeted knock-in of the polymorphism rs61764370 does not affect KRAS expression but reduces let-7 levels.Oncogenic engagement of the Met receptor is sufficient to evoke angiogenic, tumorigenic, and metastatic activities in rat intestinal epithelial cells.
P2860
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P2860
Genetic targeting of the kinase activity of the Met receptor in cancer cells
description
2007 nî lūn-bûn
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2007 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հուլիսին հրատարակված գիտական հոդված
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2007年の論文
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2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
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2007年論文
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2007年论文
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name
Genetic targeting of the kinase activity of the Met receptor in cancer cells
@ast
Genetic targeting of the kinase activity of the Met receptor in cancer cells
@en
Genetic targeting of the kinase activity of the Met receptor in cancer cells
@nl
type
label
Genetic targeting of the kinase activity of the Met receptor in cancer cells
@ast
Genetic targeting of the kinase activity of the Met receptor in cancer cells
@en
Genetic targeting of the kinase activity of the Met receptor in cancer cells
@nl
prefLabel
Genetic targeting of the kinase activity of the Met receptor in cancer cells
@ast
Genetic targeting of the kinase activity of the Met receptor in cancer cells
@en
Genetic targeting of the kinase activity of the Met receptor in cancer cells
@nl
P2860
P50
P356
P1476
Genetic targeting of the kinase activity of the Met receptor in cancer cells
@en
P2093
Alberto Pisacane
P2860
P304
P356
10.1073/PNAS.0703205104
P407
P577
2007-07-03T00:00:00Z