Brd4 links chromatin targeting to HPV transcriptional silencing - Wikidata - awgldk - TriplyDB

Brd4 links chromatin targeting to HPV transcriptional silencing

Brd4 links chromatin targeting to HPV transcriptional silencing

http://www.wikidata.org/entity/Q24676251

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Brd4 recruits P-TEFb to chromosomes at late mitosis to promote G1 gene expression and cell cycle progression Phospho switch triggers Brd4 chromatin binding and activator recruitment for gene-specific targeting Crosstalk between sumoylation and acetylation regulates p53-dependent chromatin transcription and DNA binding Genome analysis identifies the p15ink4b tumor suppressor as a direct target of the ZNF217/CoREST complex Brd4-independent transcriptional repression function of the papillomavirus e2 proteins Identification of a Chemical Probe for Bromo and Extra C-Terminal Bromodomain Inhibition through Optimization of a Fragment-Derived Hit The Bromodomain and Extra-Terminal Domain (BET) Family: Functional Anatomy of BET Paralogous Proteins Viral Genome Tethering to Host Cell Chromatin: Cause and Consequences The Role of the DNA Damage Response throughout the Papillomavirus Life Cycle Epigenome-modifying tools in asthma The mechanisms behind the therapeutic activity of BET bromodomain inhibition BET domain co-regulators in obesity, inflammation and cancer Regulation of MYC expression and differential JQ1 sensitivity in cancer cells Brd4 associates with mitotic chromosomes throughout early zebrafish embryogenesis Bromodomain protein Brd4 plays a key role in Merkel cell polyomavirus DNA replication Analysis of the papillomavirus E2 and bromodomain protein Brd4 interaction using bimolecular fluorescence complementation Interaction of NCOR/SMRT Repressor Complexes with Papillomavirus E8^E2C Proteins Inhibits Viral Replication An Epigenetic Compound Library Screen Identifies BET Inhibitors That Promote HSV-1 and -2 Replication by Bridging P-TEFb to Viral Gene Promoters through BRD4 Drug Discovery Targeting Bromodomain-Containing Protein 4.Destabilization of TIP60 by human papillomavirus E6 results in attenuation of TIP60-dependent transcriptional regulation and apoptotic pathway.Papillomavirus genomes associate with BRD4 to replicate at fragile sites in the host genome.Abrogation of the Brd4-positive transcription elongation factor B complex by papillomavirus E2 protein contributes to viral oncogene repression Papillomavirus interaction with cellular chromatin.Genome-wide siRNA screen identifies SMCX, EP400, and Brd4 as E2-dependent regulators of human papillomavirus oncogene expression BET proteins are a key component of immunoglobulin gene expression.NCoR1 mediates papillomavirus E8;E2C transcriptional repression Brd4 engagement from chromatin targeting to transcriptional regulation: selective contact with acetylated histone H3 and H4.The cellular bromodomain protein Brd4 has multiple functions in E2-mediated papillomavirus transcription activation A point mutation in the DNA-binding domain of HPV-2 E2 protein increases its DNA-binding capacity and reverses its transcriptional regulatory activity on the viral early promoter.Molecular mechanisms of retroviral integration site selection.Human T-lymphotropic virus type 1 Tax protein complexes with P-TEFb and competes for Brd4 and 7SK snRNP/HEXIM1 binding.Protein kinase WNK3 regulates the neuronal splicing factor Fox-1 Recruitment of Brd4 to the human papillomavirus type 16 DNA replication complex is essential for replication of viral DNA.Brd4 is displaced from HPV replication factories as they expand and amplify viral DNA NRIP, a novel calmodulin binding protein, activates calcineurin to dephosphorylate human papillomavirus E2 protein.The Brd4 extraterminal domain confers transcription activation independent of pTEFb by recruiting multiple proteins, including NSD3.Small molecule inhibitors of human papillomavirus protein - protein interactions.Perturbation of BRD4 protein function by BRD4-NUT protein abrogates cellular differentiation in NUT midline carcinoma Replication and partitioning of papillomavirus genomes.Binding site specificity and factor redundancy in activator protein-1-driven human papillomavirus chromatin-dependent transcription.

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Brd4 links chromatin targeting to HPV transcriptional silencing

http://www.wikidata.org/entity/Q24676251

description

2006 nî lūn-bûn

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2006 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2006 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2006年の論文

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2006年論文

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2006年論文

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2006年論文

@zh-hk

2006年論文

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2006年論文

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2006年论文

@wuu

name

Brd4 links chromatin targeting to HPV transcriptional silencing

@ast

Brd4 links chromatin targeting to HPV transcriptional silencing

@en

Brd4 links chromatin targeting to HPV transcriptional silencing

@nl

type

label

Brd4 links chromatin targeting to HPV transcriptional silencing

@ast

Brd4 links chromatin targeting to HPV transcriptional silencing

@en

Brd4 links chromatin targeting to HPV transcriptional silencing

@nl

prefLabel

Brd4 links chromatin targeting to HPV transcriptional silencing

@ast

Brd4 links chromatin targeting to HPV transcriptional silencing

@en

Brd4 links chromatin targeting to HPV transcriptional silencing

@nl

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Genes & Development

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Brd4 links chromatin targeting to HPV transcriptional silencing

@en

P2093

A-Young Lee

http://www.w3.org/2001/XMLSchema#string

Cheng-Ming Chiang

http://www.w3.org/2001/XMLSchema#string

Jongsook Kim Kemper

http://www.w3.org/2001/XMLSchema#string

Samuel Y Hou

http://www.w3.org/2001/XMLSchema#string

Shwu-Yuan Wu

http://www.w3.org/2001/XMLSchema#string

P2860

Immunoaffinity purification and functional characterization of human transcription factor IIH and RNA polymerase II from clonal cell lines that conditionally express epitope-tagged subunits of the multiprotein complexes

A bromodomain protein, MCAP, associates with mitotic chromosomes and affects G(2)-to-M transition

The bromodomain protein Brd4 is a positive regulatory component of P-TEFb and stimulates RNA polymerase II-dependent transcription

A Mammalian bromodomain protein, brd4, interacts with replication factor C and inhibits progression to S phase

RING3 kinase transactivates promoters of cell cycle regulatory genes through E2F

Structure and function of a human TAFII250 double bromodomain module

Bromodomain factor 1 corresponds to a missing piece of yeast TFIID.

The bromodomain: a chromatin-targeting module?

BRD4-NUT fusion oncogene: a novel mechanism in aggressive carcinoma

Selective recognition of acetylated histones by bromodomain proteins visualized in living cells

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2383-96

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scholarly article

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2390694

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10.1101/GAD.1448206

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17

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20

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Hediye Erdjument-Bromage

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2006-09-01T00:00:00Z

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6867245

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16921027

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1560413

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