Huntington's disease: a clinical, genetic and molecular model for polyglutamine repeat disorders
about
A broad phenotypic screen identifies novel phenotypes driven by a single mutant allele in Huntington's disease CAG knock-in mice.Intergenerational and striatal CAG repeat instability in Huntington's disease knock-in mice involve different DNA repair genesMsh2 acts in medium-spiny striatal neurons as an enhancer of CAG instability and mutant huntingtin phenotypes in Huntington's disease knock-in miceA monoclonal antibody TrkB receptor agonist as a potential therapeutic for Huntington's disease.Oxidative stress and programmed cell death in yeast.Somatic expansion of the Huntington's disease CAG repeat in the brain is associated with an earlier age of disease onset.Modifications of p53 and the DNA damage response in cells expressing mutant form of the protein huntingtin.Discovery of Small Molecules that Induce the Degradation of Huntingtin.Epigenetics of Huntington's Disease.HttQ111/+ Huntington's Disease Knock-in Mice Exhibit Brain Region-Specific Morphological Changes and Synaptic Dysfunction.
P2860
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P2860
Huntington's disease: a clinical, genetic and molecular model for polyglutamine repeat disorders
description
1999 nî lūn-bûn
@nan
1999 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Huntington's disease: a clinic ...... polyglutamine repeat disorders
@ast
Huntington's disease: a clinic ...... polyglutamine repeat disorders
@en
Huntington's disease: a clinic ...... polyglutamine repeat disorders
@nl
type
label
Huntington's disease: a clinic ...... polyglutamine repeat disorders
@ast
Huntington's disease: a clinic ...... polyglutamine repeat disorders
@en
Huntington's disease: a clinic ...... polyglutamine repeat disorders
@nl
prefLabel
Huntington's disease: a clinic ...... polyglutamine repeat disorders
@ast
Huntington's disease: a clinic ...... polyglutamine repeat disorders
@en
Huntington's disease: a clinic ...... polyglutamine repeat disorders
@nl
P2860
P356
P1476
Huntington's disease: a clinic ...... polyglutamine repeat disorders
@en
P2093
P S Harper
P2860
P304
P356
10.1098/RSTB.1999.0446
P407
P577
1999-06-29T00:00:00Z